Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the
last update. This page was most recently revised on June 27, 2020.
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
PEG-50 Shea Butter
Role:
Non-medicinal
NHPID Name:
Vitis Vinifera (Grape) Leaf Extract
Role:
Non-medicinal
NHPID Name:
Usnea Californica
Role:
Medicinal
NHPID Name:
Acheta Domesticus
Role:
Medicinal
NHPID Name:
Microchloropsis Salina
Role:
Medicinal
NHPID Name:
Eruca sativa
Role:
Medicinal
NHPID Name:
Barbarea verna
Role:
Medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
NHPID Name:
Polyhexamethylene biguanide
Role:
Non-NHP
NHPID Name:
Polyaminopropyl biguanide
Role:
Non-medicinal
NHPID Name:
SD Alcohol 3-C
Role:
Non-medicinal
NHPID Name:
SD Alcohol 36
Role:
Non-medicinal
NHPID Name:
SDAG-26
Role:
Non-medicinal
NHPID Name:
SDAG-25
Role:
Non-medicinal
NHPID Name:
SDAG-23
Role:
Non-medicinal
NHPID Name:
SDAG-21
Role:
Non-medicinal
NHPID Name:
SDAG-20
Role:
Non-medicinal
NHPID Name:
SDAG-19
Role:
Non-medicinal
NHPID Name:
SDAG-17
Role:
Non-medicinal
NHPID Name:
SDAG-14
Role:
Non-medicinal
NHPID Name:
SDAG-13
Role:
Non-medicinal
NHPID Name:
SDAG-12
Role:
Non-medicinal
NHPID Name:
SDAG-11
Role:
Non-medicinal
NHPID Name:
SDAG-10
Role:
Non-medicinal
NHPID Name:
SDAG-9
Role:
Non-medicinal
NHPID Name:
SDAG-7
Role:
Non-medicinal
NHPID Name:
SDAG-5
Role:
Non-medicinal
NHPID Name:
SDAG-2
Role:
Non-medicinal
NHPID Name:
SDAG-1
Role:
Non-medicinal
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Geranyl acetate
New NHPID Name:
Geranyl Acetate
Old NHPID Name:
Hexyl acetate
New NHPID Name:
Hexyl Acetate
Old NHPID Name:
gamma-Undecalactone
New NHPID Name:
Gamma-Undecalactone
Old NHPID Name:
Allyl hexanoate
New NHPID Name:
Allyl Hexanoate
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
Tramiprosate
New Proper Name(s):
3-Aminopropane sulfonic acid
NHPID Name:
Geranyl Acetate
Removed Proper Name(s):
2,6-Octadien-1-ol, 3,7-dimethyl-, 1-acetate, (2E)-
NHPID Name:
Geranyl Acetate
New Proper Name(s):
3,7-Dimethyl-2,6-octadien-1-yl acetate
NHPID Name:
Hexyl Acetate
Removed Proper Name(s):
Acetic acid, hexyl ester
NHPID Name:
Hexyl Acetate
New Proper Name(s):
Acetic acid, hexyl ester
NHPID Name:
Hexyl Acetate
Removed Common Name(s):
hexyl acetate
NHPID Name:
Hexyl Acetate
New Common Name(s):
Hexyl acetate
NHPID Name:
Decanal
Removed Common Name(s):
1-Decanal(mixed isomers)
• 1-Decyl aldehyde
• Aldehyde C10
• C-10 aldehyde
• Capraldehyde
• Capric aldehyde
• Caprinaldehyde
• Caprinic aldehyde
• Decaldehyde
• Decanal
• Decyl aldehyde
NHPID Name:
Gamma-Undecalactone
Removed Proper Name(s):
gamma-Undecalactone
NHPID Name:
Gamma-Undecalactone
New Proper Name(s):
5-Hydroxyundecanoic acid lactone
NHPID Name:
Gamma-Undecalactone
New Common Name(s):
gamma-Undecalactone, Peach aldehyde
NHPID Name:
Gamma-Undecalactone
Removed Common Name(s):
1,4-Hendecanolide
• 2(3H)-Furanone, 5-heptyldihydro-
• 4-undecanolide
• 5-Heptyldihydro-2(3H)-furanone
• 5-heptyloxolan-2-one
• Aldehyde C-14 peach
• aldehyde c-14 pure (so-called)
• gamma-Heptyl butyrolactone
• gamma-Undecyl lactone
• Peach Aldehyde
• Undeca-1,4-lactone
• Undecan-4-olide
• Undecano-1,4-lactone
• Undecanoic acid, 4-hydroxy-, gamma-lactone
NHPID Name:
Allyl Hexanoate
Removed Proper Name(s):
Allyl hexanoate
NHPID Name:
Allyl Hexanoate
New Proper Name(s):
Hexanoic acid, 2-propenyl ester
NHPID Name:
Allyl Hexanoate
New Common Name(s):
Allyl caproate ; Allyl hexanoate
NHPID Name:
Allyl Hexanoate
Removed Common Name(s):
2-Propenyl hexanoate
• Allyl Caproate
• allyl hexanoate
• Hexanoic acid, 2-propenyl ester
• Hexanoic acid, allyl ester
• prop-2-enyl hexanoate
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
No Changes.
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Tramiprosate
Non-medicinal Restriction(s) changed:
Revised Detail: For topical use only.
NHPID Name:
Linalyl acetate
Non-medicinal Restriction(s) changed:
Removed Detail: Flavouring agent only
NHPID Name:
Linalyl acetate
New Non-medicinal Restriction(s) added:
General
NHPID Name:
Geranyl Acetate
Non-medicinal Restriction(s) changed:
• Removed Detail: Flavouring agent only
• Revised Reference: FCC
NHPID Name:
Geranyl Acetate
New Non-medicinal Restriction(s) added:
General
NHPID Name:
Hexyl Acetate
Non-medicinal Restriction(s) changed:
Removed Detail: Flavouring agent only
• Revised Reference: FCC
NHPID Name:
Hexyl Acetate
New Non-medicinal Restriction(s) added:
Route Of Administration:
Topical
.
Allowed Purposes:
Fragrance Ingredient
.
Reference:
ICID
NHPID Name:
Raspberry ketone
Non-medicinal Restriction(s) changed:
Removed Detail: Flavouring agent only
Revised Reference: FHFI_2010
NHPID Name:
Raspberry ketone
New Non-medicinal Restriction(s) added:
General
NHPID Name:
Decanal
Non-medicinal Restriction(s) changed:
Removed Detail: Flavouring agent only
• Revised Reference: WHO_JECFA
NHPID Name:
Decanal
New Non-medicinal Restriction(s) added:
Route Of Administration:
Topical
.
Allowed Purposes:
Fragrance Ingredient
.
Reference:
ICID
NHPID Name:
Gamma-Undecalactone
Non-medicinal Restriction(s) changed:
Removed Detail: Flavouring agent only
• Revised Reference: WHO_JECFA
NHPID Name:
Gamma-Undecalactone
New Non-medicinal Restriction(s) added:
Route Of Administration:
Topical
.
Allowed Purposes:
Fragrance Ingredient
.
Reference:
ICID
.
NHPID Name:
Allyl Hexanoate
Non-medicinal Restriction(s) changed:
• Revised Detail: The level of free allyl alcohol in the ester should be less than 0.1%. / Le taux d'alcool allylique libre dans l'ester doit être inférieur à 0,1%.
• Revised Reference: FCC
NHPID Name:
Allyl Hexanoate
New Non-medicinal Restriction(s) added:
Route Of Administration:
Topical
.
Allowed Purposes:
Fragrance Ingredient
.
Detail:
The level of free allyl alcohol in the ester should be less than 0.1%.
.
Reference:
CosIng
.
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
Proanthocyanidins
New Source Material(s) added:
Hippophae rhamnoides - Fruit
NHPID Name:
Hippophae rhamnoides
New Sub-ingredient(s) added:
Proanthocyanidins
NHPID Name:
Hippophae rhamnoides
New Name Reference added:
NNHPD
NHPID Name:
Linalyl acetate
Toxicity Restriction changed:
New Upper Limit: 0.5
• New Units: Milligrams/kilogram body weight/day
• Revised Detail: Group acceptable daily intake up to 0.5 mg/kg bw/day for citral, geranyl acetate, citronellol, linalool, and linalyl acetate, expressed as citral equivalents. / Dose journalière acceptable de groupe jusqu'à 0,5 mg/kg pc/jour pour le citral, l'acétate de géranyle, le citronellol, le linalool et l'acétate de linallyle, exprimée en équivalents de citral.
NHPID Name:
Linalyl acetate
New Name Reference added:
WHO_JECFA
NHPID Name:
Linalyl acetate
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Gallic acid
New Source Material(s) added:
Labisia pumila
NHPID Name:
Labisia pumila
New Sub-ingredient(s) added:
Gallic acid
NHPID Name:
Labisia pumila
New Name Reference added:
NNHPD
NHPID Name:
Geranyl Acetate
New Name Reference added:
FCC
NHPID Name:
Geranyl Acetate
CAS Registry Number(s) removed:
130396-84-8; 8022-83-1
NHPID Name:
Geranyl Acetate
New Toxicity restriction added:
Upper Limit: 0.5
• Units: Milligrams/kilogram body weight/day
• Detail: Group acceptable daily intake up to 0.5 mg/kg bw/day for citral, geranyl acetate, citronellol, linalool, and linalyl acetate, expressed as citral equivalents.
• Reference: WHO_JECFA
NHPID Name:
Geranyl Acetate
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Hexyl Acetate
New Name Reference added:
FCC
NHPID Name:
Hexyl Acetate
New Name Reference added:
FCC
NHPID Name:
Hexyl Acetate
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Raspberry ketone
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Decanal
New Name Reference added:
FCC
NHPID Name:
Decanal
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Gamma-Undecalactone
New Name Reference added:
WHO_JECFA
NHPID Name:
Gamma-Undecalactone
CAS Registry Number(s) removed:
57084-17-0
NHPID Name:
Gamma-Undecalactone
Toxicity Restriction changed:
Upper Limit:
1.25
.
Units:
Milligrams/kilogram body weight/day
.
Detail:
Acceptable daily intake up to 1.25 mg/kg bw/day.
.
Reference:
WHO_JECFA
NHPID Name:
Gamma-Undecalactone
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Allyl Hexanoate
New Name Reference added:
FCC
NHPID Name:
Allyl Hexanoate
Toxicity Restriction changed:
Upper Limit:
0.13
.
Units:
Milligrams/kilogram body weight/day
.
Detail:
Acceptable daily intake up to 0.13 mg/kg bw/day.
.
Reference:
WHO_JECFA
.
.
NHPID Name:
Allyl Hexanoate
New NMI Purpose(s):
Fragrance Ingredient
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
No Changes.
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
No Changes.
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
RemIng
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