Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on January 23, 2018.
- Announcements
- New Ingredients
- Removed Ingredients
- Revised NHPID Names
- Revised Proper and Common Names
- New Roles
- Revised Restrictions
- Other Ingredient Modifications
- Monograph Modifications
- AbLS Modifications
- Controlled Vocabulary Modifications
- Homeopathic Ingredient Modifications
- Previous What's New
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
Coconut flour
Role:
Non-medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
No Changes.
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Polyaminopropyl biguanide hydrochloride
New NHPID Name:
Polihexanide
Old NHPID Name:
p-Menth-1-ene-8-thiol
New NHPID Name:
1-p-Menthene-8-thiol
Old NHPID Name:
Benzyl methyl disulfide
New NHPID Name:
Methyl benzyl disulfide
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
Polyaminopropyl biguanide hydrochloride
New Proper Name(s):
Poly(iminocarbonimidoyl-imino-carbonimidoylimino-1,6-hexanediyl) hydrochloride (1:?)
Polyhexamethylene biguanide hydrochloride
NHPID Name:
Polyaminopropyl biguanide hydrochloride
New Common Name(s):
PHMB; Polyaminopropyl biguanide
NHPID Name:
Ambrettolide
New Proper Name(s):
Oxacycloheptadec-7-en-2-one
NHPID Name:
colloidal sulfur
New Common Name(s):
Colloidal sulfur in acacia gum
NHPID Name:
colloidal sulfur
New Proper Name(s):
colloidal sulfur
NHPID Name:
p-Menth-1-ene-8-thiol
New Proper Name(s):
3-Cyclohexene-1-methanethiol, alpha,alpha,4-trimethyl-
NHPID Name:
p-Menth-1-ene-8-thiol
Removed Common Name(s):
p-Menth-1-ene-8-thiol
NHPID Name:
p-Menth-1-ene-8-thiol
New Common Name(s):
1-p-Menthene-8-thiol
NHPID Name:
Benzyl methyl disulfide
New Common Name(s):
Methyl benzyl disulfide
NHPID Name:
Diallyl trisulfide
Removed Proper Name(s):
Diallyl trisulfide
NHPID Name:
Diallyl trisulfide
New Proper Name(s):
Di-2-propen-1-yl trisulfide
NHPID Name:
Diallyl trisulfide
Removed Common Name(s):
3-prop-2-enylsulfanyldisulfanylprop-1-ene; Di-2-propenyl trisulfide; Prop-2-enyltrithio prop-2-ene; Trisulfide, di-2-propenyl
NHPID Name:
Diallyl trisulfide
New Common Name(s):
Diallyl trisulfide
NHPID Name:
Aronia melanocarpa (Black chokeberry) fruit juice concentrate
New Common Name(s):
Aronia melanocarpa (Black chokeberry) fruit juice concentrate
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
NHPID Name:
Selenium amino acid chelate
Old Role:
Medicinal
New Role:
No role
NHPID Name:
colloidal sulfur
Old Role:
No role
New Role:
Non-medicinal
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Polyaminopropyl biguanide hydrochloride
New Route(s) of Adminstration added:
Topical:For topical use only, up to 0.1%. Not permitted in sprayable formulations
NHPID Name:
Polyurethane-1
New Route(s) of Adminstration added:
For topical use only, up to 15%.
NHPID Name:
Isoeugenyl benzyl ether
Route(s) of Adminstration removed:
Flavouring agent only, up to 1.5 mcg/kg body weight/day
NHPID Name:
Isoeugenyl phenylacetate
Route(s) of Adminstration removed:
Flavouring agent only, up to 30 mcg/kg body weight/day
NHPID Name:
3-Phenylpropyl cinnamate
Route(s) of Adminstration removed:
Flavouring agent only, up to 30 mcg/kg body weight/day
NHPID Name:
Phenyl acetate
Route(s) of Adminstration removed:
Flavouring agent only, up to 0.0025 mcg/kg body weight/day
NHPID Name:
Ambrettolide
Route(s) of Adminstration removed:
Flavouring agent only.
NHPID Name:
Methyl-alpha-ionone
Route(s) of Adminstration removed:
Flavouring agent only.
NHPID Name:
cyclohexanone
Route(s) of Adminstration removed:
Flavouring agent only
NHPID Name:
alpha-ionone
Route(s) of Adminstration removed:
Flavouring agent only
NHPID Name:
beta-ionone
Route(s) of Adminstration removed:
Flavouring agent only
NHPID Name:
gamma-ionone
Route(s) of Adminstration removed:
Flavouring agent only
NHPID Name:
alpha-isomethyl ionone
New Route(s) of Adminstration added:
Oral, topical
NHPID Name:
colloidal sulfur
New Route(s) of Adminstration added:
Topical use only. Colloidal sulfur in a base of acacia gum which may contain trace amounts of propylene glycol or glycerin.
NHPID Name:
colloidal sulfur
New Route(s) of Adminstration added:
Topical
NHPID Name:
colloidal sulfur
New Route(s) of Adminstration added:
Cosmetic Biocide, Skin-Conditioning Agent
NHPID Name:
Diallyl trisulfide
New Route(s) of Adminstration added:
Flavouring agent only, up to 0.0046 mg/kg bw/day.
NHPID Name:
Aronia melanocarpa (Black chokeberry) fruit juice concentrate
New Route(s) of Adminstration added:
Oral use only.
NHPID Name:
Aronia melanocarpa (Black chokeberry) fruit juice concentrate
New Restriction Reference added:
CORNU 2
NHPID Name:
Polyurethane-11
Non-medicinal Restriction(s) changed:
For topical use only, up to 5.2%.
NHPID Name:
Polyurethane-11
New Restriction Reference added:
CIR
NHPID Name:
Polyurethane-2
Non-medicinal Restriction(s) changed:
For topical use only, up to 9%.
NHPID Name:
Polyurethane-2
New Restriction Reference added:
CIR
NHPID Name:
Polyurethane-29
Non-medicinal Restriction(s) changed:
For topical use only.
NHPID Name:
Polyurethane-35
Non-medicinal Restriction(s) changed:
For topical use only, up to 7%.
NHPID Name:
Polyurethane-35
New Restriction Reference added:
CIR
NHPID Name:
Polyurethane-40
Non-medicinal Restriction(s) changed:
For topical use only.
NHPID Name:
Polyurethane-40
New Restriction Reference added:
ICID
NHPID Name:
Polyurethane-62
Non-medicinal Restriction(s) changed:
For topical use only.
NHPID Name:
Polyurethane-64
Non-medicinal Restriction(s) changed:
For topical use only.
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
Calcium
New Source Ingredient(s) added:
Salmo salar
NHPID Name:
Medium-chain triglycerides
New Sub-ingredient(s) added:
Octanoic acid
NHPID Name:
Medium-chain triglycerides
New Sub-ingredient(s) added:
Capric Acid
NHPID Name:
Brassica oleracea var. italica
New Sub-ingredient(s) added:
Sulforaphane
NHPID Name:
Paeoniflorin
Source Material(s) removed:
Paeonia lactiflora
NHPID Name:
Polyaminopropyl biguanide hydrochloride
Non-NHP Rationale changed:
A non-NHP because not a naturally occurring substance included in Schedule 1 of the Natural Health Products Regulations.
NHPID Name:
Pyrogallol
New Toxicity restriction added:
Threshold of toxicological concern of 0.0025 mcg/kg bw/day.
NHPID Name:
Pyrogallol
Additional Details changed:
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient cannot be used in topical natural health products without the submission of additional evidence for safety. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php.
NHPID Name:
Isoeugenyl benzyl ether
New Toxicity restriction added:
Threshold of toxicological concern of 1.5 mcg/kg bw/day.
NHPID Name:
Isoeugenyl phenylacetate
New Toxicity restriction added:
Threshold of toxicological concern of 30 mcg/kg bw/day.
NHPID Name:
3-Phenylpropyl cinnamate
New Toxicity restriction added:
Threshold of toxicological concern of 30 mcg/kg bw/day.
NHPID Name:
alpha-ionone
Toxicity Restriction changed:
Acceptable daily intake of up to 0.1 mg/kg bw/day for alpha-ionone and beta-ionone, singly or in combination.
NHPID Name:
beta-ionone
Toxicity Restriction changed:
Acceptable daily intake of up to 0.1 mg/kg bw/day for alpha-ionone and beta-ionone, singly or in combination.
NHPID Name:
gamma-ionone
Toxicity Restriction removed:
Acceptable daily intake up to 0.1 mg/kg body weight daily (JECFA, 1998) for alpha-ionone, beta-ionone, gamma-ionone singly or in combination.
NHPID Name:
Syzygium aromaticum
New Sub-ingredient(s) added:
beta-Caryophyllene
NHPID Name:
dibenzyl disulfide
New Name Reference added:
MI
NHPID Name:
p-Menth-1-ene-8-thiol
New Name Reference added:
JECFA
NHPID Name:
Benzyl methyl disulfide
New Name Reference added:
JECFA
NHPID Name:
Cyclopentanethiol
New Name Reference added:
JECFA
NHPID Name:
Diallyl trisulfide
New Name Reference added:
MI
NHPID Name:
Ascophyllum nodosum ( Parts: Thallus )
New Sub-ingredient(s) added:
Fucoxanthin
NHPID Name:
Aronia melanocarpa (Black chokeberry) fruit juice concentrate
New Method(s) of Preparation added:
Concentrated juice
NHPID Name:
Aronia melanocarpa (Black chokeberry) fruit juice concentrate
New NMI Purpose(s):
Flavour Enhancer
NHPID Name:
Protein
New Source Ingredient(s) added:
Gallus gallus ( Parts: Egg white )
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
No Changes.
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
Modification:
C10-13 Alkane
Modification:
C14-22 Alkane
Modification:
C18-21 Alkane
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
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