Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the
last update. This page was most recently revised on March 20, 2020.
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
Cordyceps Militaris Mycelium Extract
Role:
Non-medicinal
NHPID Name:
Sorbityl Laurate
Role:
Non-medicinal
NHPID Name:
lactobacillus
Role:
Non-medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
No Changes.
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Artemisia abrotanum Extract
New NHPID Name:
Artemisia Abrotanum Extract
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
Diisopropanolamine
New Proper Name(s):
1,1'-Iminodipropan-2-ol
NHPID Name:
Diisopropanolamine
Removed Proper Name(s):
Diisopropanolamine
NHPID Name:
Diisopropanolamine
New Common Name(s):
Diisopropanolamine
NHPID Name:
Diisopropanolamine
Removed Common Name(s):
1,1'-Iminodipropan-2-ol
NHPID Name:
Diisopropanolamine
Removed Common Name(s):
2-Propanol, 1,1'-iminobis-
NHPID Name:
isopropanolamine
New Proper Name(s):
1-Amino-2-propanol
NHPID Name:
isopropanolamine
Removed Proper Name(s):
isopropanolamine
NHPID Name:
isopropanolamine
New Common Name(s):
isopropanolamine
NHPID Name:
triisopropanolamine
Removed Proper Name(s):
triisopropanolamine
NHPID Name:
triisopropanolamine
New Proper Name(s):
1,1',1"-Nitrilotris-2-propanol
NHPID Name:
Artemisia Abrotanum Extract
Removed Common Name(s):
Southern wormwood Extract
NHPID Name:
Artemisia Abrotanum Extract
Removed Common Name(s):
Artemisia abrotanum Extract
NHPID Name:
Artemisia Abrotanum Extract
New Common Name(s):
Artemisia abrotanum extract
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
NHPID Name:
Magnesium ascorbate
Old Role:
Medicinal
New Role:
No role
NHPID Name:
DL-Tartaric acid
Old Role:
No role
New Role:
Non-NHP
NHPID Name:
D-Tartaric acid
Old Role:
No role
New Role:
Non-NHP
NHPID Name:
L-Tartaric acid
Old Role:
No role
New Role:
Non-NHP
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Diisopropanolamine
New Route(s) of Adminstration added:
Topical
NHPID Name:
Diisopropanolamine
New Restriction Reference added:
CIR
NHPID Name:
Diisopropanolamine
Restriction Reference removed:
UNAVA
NHPID Name:
isopropanolamine
New Restriction Reference added:
CIR
NHPID Name:
isopropanolamine
Restriction Reference removed:
UNAVA
NHPID Name:
triisopropanolamine
New Restriction Reference added:
CIR
NHPID Name:
triisopropanolamine
Restriction Reference removed:
ICID
NHPID Name:
Tetrahydrocurcuminoids
Non-medicinal Restriction(s) removed:
General
NHPID Name:
alpha-Cyclodextrin
Non-medicinal Restriction(s) removed:
General
NHPID Name:
gamma-Cyclodextrin
Non-medicinal Restriction(s) removed:
General
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
Non-medicinal Restriction(s) removed:
General
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
New Restriction Reference added:
EQSAFTY2
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
Restriction Reference removed:
CosIng
NHPID Name:
Cinnamon Essential Oil
Non-medicinal Restriction(s) changed:
Acceptable daily intake added:
Upper Limit:2.5
Units:Milligrams/kilogram body weight/day
Route Of Administration:Oral
Detail:Acceptable daily intake up to 2.5 mg/kg bw/day, expressed as eugenol equivalents.
Reference:WHO_JECFA
NHPID Name:
Turpentine essential oil
Non-medicinal Restriction(s) removed:
General
NHPID Name:
Shark Liver Oil
New Route(s) of Adminstration added:
Topical
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
Proanthocyanidins
New Source Material(s) added:
Pinus pinaster (Parts: Stem bark)
NHPID Name:
Glucosamine hydrochloride
New Source Material(s) added:
Escherichia coli (Parts: Whole Cell for Biosynthesis)
NHPID Name:
Diisopropanolamine
Modification:
New Restriction detail: For topical use only, up to 0.7%, and not to be used in products containing N-nitrosating agents.
NHPID Name:
isopropanolamine
Modification:
New Restriction detail: For topical use only, up to 1%, and not to be used in products containing N-nitrosating agents.
NHPID Name:
triisopropanolamine
Modification:
Revised Restriction detail: For topical use only, up to 1%, and not to be used in products containing N-nitrosating agents.
NHPID Name:
phytosterols
New Source Material(s) added:
Pinus sylvestris (Parts: Trunk bark)
NHPID Name:
Tetrahydrocurcuminoids
Modification:
Revised Schedule 1: Extract
NHPID Name:
Tetrahydrocurcuminoids
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.
NHPID Name:
Magnesium ascorbate
Modification:
Removed Schedule 1: Synthetic duplicate
NHPID Name:
alpha-Cyclodextrin
Modification:
Revised Schedule 1: Isolate
NHPID Name:
alpha-Cyclodextrin
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an isolate) of the Natural Health Products Regulations.
NHPID Name:
gamma-Cyclodextrin
Modification:
Revised Schedule 1: Isolate
NHPID Name:
gamma-Cyclodextrin
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an isolate) of the Natural Health Products Regulations.
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
New Name Reference added:
ICID
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
Modification:
Removed Schedule 1: Extract
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
Method(s) of Preparation removed:
Oil, Essential (water steam distillation) Standardized
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
Removed NMI purpose(s):
Flavour Enhancer - Natural
NHPID Name:
Cinnamomum Zeylanicum Leaf Oil
Modification:
Revised Restriction detail: For topical use only, up to 6%.
NHPID Name:
Cinnamon Essential Oil
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.
NHPID Name:
Turpentine essential oil
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.
NHPID Name:
Turpentine oil
Modification:
Revised Parts: Gum oleoresin
NHPID Name:
Turpentine oil
Method(s) of Preparation removed:
Oil, Essential (water steam distillation) Standardized, Oil, Essential (enfleurage); Oil, Essential (enfleurage) Standardized; Oil, Essential (expression); Oil, Essential (expression) Standardized; Oil, Essential (other methods of preparation); Oil, Essential (other methods of preparation) Standardized
NHPID Name:
Turpentine oil
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.
NHPID Name:
Turpentine oil
Modification:
New Restriction detail: For topical use only
NHPID Name:
Artemisia Abrotanum Extract
Modification:
Removed Schedule 1: plant and plant material
NHPID Name:
Artemisia Abrotanum Extract
New Source Material(s) added:
Artemisia abrotanum
(Parts: Whole plant)
NHPID Name:
Artemisia Abrotanum Extract
Source Material(s) removed:
Artemisia abrotanum
(Parts: Whole)
NHPID Name:
Artemisia Abrotanum Extract
Method(s) of Preparation removed:
Extract dry standardized; Extract liquid standardized
NHPID Name:
Artemisia Abrotanum Extract
Modification:
New Restriction detail: For topical use only
NHPID Name:
Artemisia Vulgaris Extract
Modification:
Removed Schedule 1: Extract
NHPID Name:
Artemisia Vulgaris Extract
Method(s) of Preparation removed:
Extract dry standardized; Extract liquid standardized
NHPID Name:
Artemisia Vulgaris Extract
Modification:
New Restriction detail: For topical use only
NHPID Name:
Artemisia Pallens Flower Oil
Modification:
Removed Schedule 1: Extract
NHPID Name:
Artemisia Pallens Flower Oil
Method(s) of Preparation removed:
Oil, Essential (water steam distillation) Standardized
NHPID Name:
Artemisia Pallens Flower Oil
Modification:
New Restriction detail: For topical use only
NHPID Name:
Artemisia princeps leaf extract
Modification:
Removed Schedule 1: plant and plant material
NHPID Name:
Artemisia princeps leaf extract
Method(s) of Preparation removed:
Extract dry standardized; Extract liquid standardized
NHPID Name:
Artemisia princeps leaf extract
Modification:
New Restriction detail: For topical use only
NHPID Name:
Lamna nasus (porbeagle shark) cartilage
New Additional Details added :
It should be noted that Lamna nasus (porbeagle shark) is listed on Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora.
NHPID Name:
Lamna nasus (porbeagle shark) cartilage
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 1 (a non-human animal material) of the Natural Health Products Regulations.
NHPID Name:
Shark cartilage
Additional Details changed:
Sharks are organisms in the orders Carcharhiniformes, Heterodontiformes, Hexanchiformes, Lamniformes, Orectolobiformes, Pristiophoriformes, Squaliformes, and Squatiniformes. It should be noted that this ingredient may be subject to additional regulatory requirements depending on its source material species in accordance with the Species at Risk Act and/or the Convention on International Trade in Endangered Species of Wild Fauna and Flora.
NHPID Name:
Shark cartilage
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 1 (a non-human animal material) of the Natural Health Products Regulations.
NHPID Name:
Shark Liver Oil
Additional Details changed:
Sharks are organisms in the orders Carcharhiniformes, Heterodontiformes, Hexanchiformes, Lamniformes, Orectolobiformes, Pristiophoriformes, Squaliformes, and Squatiniformes. It should be noted that this ingredient may be subject to additional regulatory requirements depending on its source material species in accordance with the Species at Risk Act and/or the Convention on International Trade in Endangered Species of Wild Fauna and Flora.
NHPID Name:
Shark Liver Oil
Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.
NHPID Name:
L-Malic acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
L-Malic acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
Citric acid monohydrate
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
Citric acid monohydrate
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
DL-Malic acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
DL-Malic acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
D-Malic acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
D-Malic acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
Citric acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
Citric acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
Glycolic Acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
Glycolic Acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
D-Lactic acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
D-Lactic acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
DL-Lactic acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
DL-Lactic acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
L-Lactic acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
L-Lactic acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
dl-Mandelic acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
dl-Mandelic acid
Non-NHP Rationale changed:
A non-NHP when the product is captured by the Prescription Drug List: When sold in topical formulations containing alpha hydroxy acids alone or in combination at concentrations greater than 30% and/or with a pH lower than 3.0, except when sold to be applied to warts, corns or calluses.
NHPID Name:
DL-Tartaric acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
D-Tartaric acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
L-Tartaric acid
Additional Details changed:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
No Changes.
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
No Changes.
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
RemIng
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