Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on January 10, 2017.

Announcements
New Ingredients
Removed Ingredients
Revised NHPID Names
Revised Proper and Common Names
New Roles
Revised Restrictions
Other Ingredient Modifications
Monograph Modifications
AbLS Modifications
Controlled Vocabulary Modifications
Homeopathic Ingredient Modifications
Previous What's New

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1

New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:

Ethylhexyl hydroxystearate benzoate

Role:

Non-medicinal

NHPID Name:

Gamma-glutamyl phenylalanine

Role:

No role

NHPID Name:

Potassium glutarate

Role:

No role

NHPID Name:

Manganese(II) fumarate

Role:

No role

NHPID Name:

Potassium succinate

Role:

No role

NHPID Name:

Manganese (II) succinate

Role:

No role

NHPID Name:

Carica Papaya (Papaya) Leaf extract

Role:

Non-medicinal

NHPID Name:

Strongylocentrotus droebachiensis

Role:

Medicinal

NHPID Name:

Pseudowintera colorata

Role:

Medicinal

NHPID Name:

Ampelopsis grossedentata

Role:

Medicinal

Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

No Changes.

Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:

Methyl furoate

New NHPID Name:

Methyl 2-furoate

Old NHPID Name:

Pentyl 2-furoate

New NHPID Name:

Amyl 2-furoate

Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:

Benzophenone

Removed Common Name(s):

Alpha-Oxodiphenylmethane; Benzoylbenzene; Diphenyl Ketone; diphenylmethanone; Phenyl ketone

NHPID Name:

Benzophenone

New Common Name(s):

Benzophenone

NHPID Name:

Furfural

Removed Proper Name(s):

Furfural

NHPID Name:

Furfural

New Proper Name(s):

2-Furancarboxaldehyde

NHPID Name:

Furfural

Removed Common Name(s):

2-Formylfuran; 2-furaldehyde; 2-Furancarboxaldehyde; 2-Furylcarboxaldehyde; Fural; Furaldehyde; furan-2-carbaldehyde; Furfuraldehyde; furfurol; pyromucic aldehyde

NHPID Name:

5-Methylfurfural

Removed Proper Name(s):

5-Methylfurfural

NHPID Name:

5-Methylfurfural

New Proper Name(s):

5-Methyl-2-furancarboxaldehyde

NHPID Name:

5-Methylfurfural

Removed Common Name(s):

2-Furaldehyde, 5-methyl-; 2-Furancarboxaldehyde, 5-methyl-; 5-Methyl-2-furaldehyde; 5-Methyl-2-furfural; 5-methylfuran-2-carbaldehyde; 5-Methyl furfural

NHPID Name:

5-Methylfurfural

New Common Name(s):

5-Methylfurfural

NHPID Name:

2-Phenyl-3-carbethoxyfuran

Removed Proper Name(s):

3-Furancarboxylic acid, 2-phenyl-, ethyl ester; Ethyl 2-Phenyl-3-furoate

NHPID Name:

2-Phenyl-3-carbethoxyfuran

New Common Name(s):

2-Phenyl-3-carbethoxyfuran

NHPID Name:

Methyl 2-furoate

Removed Common Name(s):

Methyl furoate

NHPID Name:

Methyl 2-furoate

New Common Name(s):

Methyl 2-furoate

NHPID Name:

Methyl 2-furoate

Removed Proper Name(s):

Furancarboxylic acid, methyl ester

NHPID Name:

Methyl 2-furoate

New Proper Name(s):

2-Furancarboxylic acid, methyl ester

NHPID Name:

Propyl 2-furoate

Removed Common Name(s):

2-Furancarboxylic acid, propyl ester; 2-Furoic acid, propyl ester; n-propyl pyromucate; propyl furan-2-carboxylate

NHPID Name:

Propyl 2-furoate

New Common Name(s):

Propyl 2-furoate

NHPID Name:

Propyl 2-furoate

Removed Proper Name(s):

Propyl 2-Furoate

NHPID Name:

Propyl 2-furoate

New Proper Name(s):

2-Furancarboxylic acid, propyl ester

NHPID Name:

Amyl 2-furoate

Removed Common Name(s):

2-furoic acid, pentyl ester; Amyl furan-2-carboxylate; Furancarboxylic acid, pentyl ester; Pentyl furan-2-carboxylate

NHPID Name:

Amyl 2-furoate

Removed Proper Name(s):

Pentyl 2-furoate

NHPID Name:

Amyl 2-furoate

New Proper Name(s):

Furancarboxylic acid, pentyl ester

NHPID Name:

Sodium PCA

New Proper Name(s):

5-Oxo-DL-Proline, Monosodium Salt

New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:

Cetyl myristate

Old Role:

No role

New Role:

Non-medicinal

NHPID Name:

Ethyl lactate

Old Role:

Non-medicinal

New Role:

Medicinal & Non-medicinal

NHPID Name:

Sanguis Cervi

Old Role:

Medicinal

New Role:

Non-NHP

NHPID Name:

Clay

Old Role:

Medicinal

New Role:

Medicinal & Non-medicinal

Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:

Benzophenone-2

New Non-medicinal Restriction(s) added:

For topical use only, up to 0.4%.

NHPID Name:

Benzophenone-4

New Non-medicinal Restriction(s) added:

For topical use only, up to 0.1%, if not contributing to the product`s claim(s).

NHPID Name:

Furfural

Non-medicinal Restriction(s) changed:

Acceptable daily intake up to 0.5 mg/kg bw/day.

NHPID Name:

Cinnamomum Zeylanicum Bark Oil

New Non-medicinal Restriction(s) added:

Maximum concentration permitted for topical uses Fragrance ingredient and Masking agent: 0.07% (IFRA2009; Tisserand and Young 2014).

NHPID Name:

Sanguis Cervi

Medicinal Restriction(s) removed:

Deer blood is sourced from an animal susceptible to Transmissible Spongiform Encephalopathy (TSE). In order to minimize the risk of TSEs, please ensure the following procedures are in place: Source animals are fit for human consumption; materials can be traced back to source (herd or animal); avoidance of cross contamination with high-infectivity tissues during sourcing; and manufacturing procedures that are known to reduce infectivity (if any) are implemented (e.g. procedures that are in accordance with Chapter 5.2.8 of the European Pharmacopoeia).

NHPID Name:

Edetic acid

Non-medicinal Restriction(s) changed:

The concentration of nitrilotriacetic acid in EDTA should not exceed 0.3%.

NHPID Name:

Edetate calcium disodium

Non-medicinal Restriction(s) changed:

Up to 25 mg/kg body weight per day. Not acceptable in products with a disinfectant claim above 0.05%. The concentration of nitrilotriacetic acid in Edetate calcium disodium should not exceed 0.1%.

NHPID Name:

Disodium EDTA

Non-medicinal Restriction(s) changed:

Up to 25 mg/kg body weight per day, expressed as Edetate calcium disodium. The concentration of nitrilotriacetic acid in Disodium edetate should not exceed 0.1%.

Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:

Beta vulgaris

New Sub-ingredient(s) added:

Potassium

NHPID Name:

Benzophenone

New Toxicity restriction added:

Tolerable daily intake up to 0.03 mg/kg bw/day.

NHPID Name:

5-Methylfurfural

New Toxicity restriction added:

Acceptable daily intake up to 0.14 mg/kg bw/day, expressed as 5-hydroxymethylfurfural equivalents.

NHPID Name:

2-Benzofurancarboxaldehyde

New Toxicity restriction added:

Acceptable daily intake up to 0.25 mg/kg bw/day.

NHPID Name:

2-Phenyl-3-carbethoxyfuran

New Toxicity restriction added:

Acceptable daily intake up to 0.13 mg/kg bw/day.

NHPID Name:

Furfuryl alcohol

Toxicity Restriction changed: