Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on September 26, 2025.
- Announcements
- New Ingredients
- Removed Ingredients
- Revised NHPID Names
- Revised Proper and Common Names
- New Roles
- Revised Restrictions
- Other Ingredient Modifications
- Monograph Modifications
- AbLS Modifications
- Controlled Vocabulary Modifications
- Homeopathic Ingredient Modifications
- Previous What's New
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
Brassica oleracea var. sabauda
Role:
Medicinal
NHPID Name:
Brassica oleracea var. sabellica
Role:
Medicinal
NHPID Name:
Hydrolyzed Myrtus Communis Leaf Extract
Role:
Non-medicinal
NHPID Name:
Tea Willow
Role:
Medicinal
NHPID Name:
Sempervivum tectorum
Role:
Medicinal
NHPID Name:
Citrus depressa
Role:
Medicinal
NHPID Name:
Tripeptide-3
Role:
non-medicinal
NHPID Name:
Pentapeptide-84 Amide Acetate
Role:
non-medicinal
NHPID Name:
Heptapeptide-68 Amide Acetate
Role:
non-medicinal
NHPID Name:
Dipsacus fullonum
Role:
medicinal
NHPID Name:
Chickpea Natto
Role:
Medicinal
NHPID Name:
Calcium lactate gluconate dihydrate
Role:
No Role
NHPID Name:
Ginseng Protein Hydrolysate
Role:
Medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
No Changes.
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Gardenia Jasminoides Fruit Extract
New NHPID Name:
Gardenia Jasminoides Fruit Extract
Old NHPID Name:
Semen Phaseoli
New NHPID Name:
Semen Vignae
Old NHPID Name:
Radix Flemingiae Philippinensis
New NHPID Name:
Radix Flemingiae Prostratae
Old NHPID Name:
2-Amino-2-methyl-1-propanol
New NHPID Name:
Aminomethyl Propanol
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
HPUS_Mercurius iodatus ruber
New Proper Name(s):
Mercurius bi-iodatus
NHPID Name:
Gardenia Jasminoides Fruit Extract
Removed Common Name(s):
Gardenia Jasminoides Fruit Extract
NHPID Name:
Gardenia Jasminoides Fruit Extract
New Common Name(s):
Gardenia florida fruit extract; Gardenia jasminoides fruit extract
NHPID Name:
Citrus Limon (Lemon) Peel Oil
New Common Name(s):
Lemon peel oil
NHPID Name:
Semen Vignae
Removed Common Name(s):
Adzuki Bean Seed
NHPID Name:
Semen Vignae
New Common Name(s):
Adzuki bean; Rice bean
NHPID Name:
Radix Flemingiae Prostratae
Removed Proper Name(s):
Flemingia philippinensis
NHPID Name:
Radix Flemingiae Prostratae
New Proper Name(s):
Flemingia prostrata
NHPID Name:
Radix Flemingiae Prostratae
New Common Name(s):
Radix Flemingiae Prostratae
NHPID Name:
Trimethyl Isopropyl Butanamide
Removed Proper Name(s):
Trimethyl isopropyl butanamide
NHPID Name:
Trimethyl Isopropyl Butanamide
New Proper Name(s):
N,2,3-Trimethyl-2-(1-methylethyl)butanamide
NHPID Name:
Trimethyl Isopropyl Butanamide
Removed Common Name(s):
2-Isopropyl-N,2,3-trimethylbutyramide
NHPID Name:
Trimethyl Isopropyl Butanamide
New Common Name(s):
Methyl diisopropyl propionamide
NHPID Name:
Aminomethyl Propanol
Removed Common Name(s):
2,2-Diethylethanolamine; Aminomethyl Propanol
NHPID Name:
Aminomethyl Propanol
New Common Name(s):
Aminomethyl propanol
NHPID Name:
beta-Caryophyllene
Removed Proper Name(s):
beta-Caryophyllene
NHPID Name:
Copper (II) gluconate
Removed Proper Name(s):
Bis(D-gluconato-kappaO1,kappaO2)copper
NHPID Name:
Copper (II) gluconate
New Proper Name(s):
Bis(D-gluconato-kappaO1,kappaO2)copper
NHPID Name:
Pollen Pini
New Proper Name(s):
Pinus contorta; Pinus massoniana; Pinus ponderosa
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
No Changes.
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Mixed carotenoids
Non-medicinal Restriction(s) changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.
NHPID Name:
Zinc stearate
New Non-medicinal Restriction(s) added:
Dental - Anticaking Agent - Up to 2%, when formulated to be non-irritating.
NHPID Name:
Sodium lactate
New Non-medicinal Restriction(s) added:
For skin products, the concentration of alpha-hydroxy acids alone or in combination (including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts), when used as non-medicinal ingredients, should be lower than 3% and not contribute to the product's pharmacological effects.
NHPID Name:
Zinc stearate
New Non-medicinal Restriction(s) added:
Topical - Anticaking Agent, Colour Additive, Slip Modifier, and Viscosity Increasing Agent - Nonaqueous - Up to 32%, when formulated to be non-irritating.
NHPID Name:
Semen Lablab Album
New Medicinal Restriction(s) added :
Lablab purpureus contains hemagglutinin A. In order to reduce toxicity, the seeds must be heat processed (e.g., dry-fried) to inactivate hemagglutinin A.
NHPID Name:
Gardenia Jasminoides Fruit Extract
New Non-medicinal Restriction(s) added:
For topical use only.
NHPID Name:
Aminomethyl Propanol
Non-medicinal Restriction(s) changed:
For topical use only, up to 7%. Not to be used in products containing N-nitrosating agents.
NHPID Name:
Aminomethyl Propanol
New Non-medicinal Restriction(s) added:
Aminomethyl propanol should not to be used with N-nitrosating systems, be of minimum 99% purity, contain maximum 50 ppb nitrosamine, a maximum secondary amine content of 0.5%, and kept in nitrite-free containers.
NHPID Name:
Bovine Colostrum
New Non-medicinal Restriction(s) added:
For topical use only.
NHPID Name:
Pinelliae Fermentata
Medicinal Restriction(s) Changed :
As this is a traditional Chinese medicine (TCM) ingredient, it may only be used in accordance with the conditions of use outlined in TCM referenced texts (e.g., methods of preparation, source materials, doses, directions for use, durations of use, combinations of medicinal ingredients, risk statements, and the theory of TCM). Pinelliae Fermentata should be prepared according to the State Drug Standard (SDS) Banxia Qu monograph WS3-B-1919-95 available at: http://www.pharmnet.com.cn/search/detail--32--6815.html (in Chinese) or the Beijing Specification for the Preparation of Traditional Chinese Medicine Decoction Pieces (2023) Pinelliae Fermentata monograph available at: https://yjj.beijing.gov.cn/yjj/zwgk20/zcwj91/436479235/index.html (in Chinese) - including 1) Rhizoma Pinelliae Praeparatum cum Alumine, Alumen, Massa Medicata Fermentata, Rhizoma Zingiberis Recens, and Wheat flour; or 2) Rhizoma Pinelliae Praeparatum, Vignae Semen, Semen Armeniacae Amarum, Herba Artemisiae Annuae, Herba Polygoni Hydropiper, Herba Xanthii, and Wheat flour - respectively. The species and parts from which the ingredients used in the processing of Pinelliae Fermentata are derived should therefore be listed as source materials in the Natural Health Product Licence Application Form (web PLA form); except for Alumen (Bai fan), as this ingredient is a chemical substance and as such, not currently available for selection as a source material in the web PLA form. Note that wheat bran and wheat flour included in Massa Medicata Fermentata, as well as additional wheat flour added to Pinelliae Fermentata, can all be represented as one source material (i.e., Triticum aestivum husk and seed).
NHPID Name:
Copper (II) gluconate
New Non-medicinal Restriction(s) added:
Up to 0.36% in rinse-off products and up to 0.008% in leave-on products.
NHPID Name:
Sodium hyaluronate
New Non-medicinal Restriction(s) added:
At a dose of less than 48 mg/day, expressed in hyaluronic acid equivalents.
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
Hydrolyzed collagen type I
New Source Material(s) added:
Fish (Parts: Skin)
NHPID Name:
Mixed carotenoids
New Sub-ingredient(s) added:
Astaxanthin
NHPID Name:
Mixed carotenoids
New Source Material(s) added:
Blastobotrys adeninivorans (Parts: Whole Cell for Biosynthesis)
NHPID Name:
Astaxanthin
New Source Ingredient(s) added:
Mixed carotenoids
NHPID Name:
Sodium lactate
Additional Details changed:
Sodium is an electrolyte, not a nutrient. As a medicinal ingredient, sodium does not contribute to the maintenance of good health since there is likely to be excess sodium from the diet, not a deficiency. The safety and efficacy of sodium lactate as a source of sodium must be assessed under the recommended conditions of use. The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.
NHPID Name:
Gardenia Jasminoides Fruit Extract
New NMI Purpose(s):
Skin-Conditioning Agent
NHPID Name:
Gardenia Jasminoides Fruit Extract
Modification:
Removed: Schedule 1: Plant and plant material
NHPID Name:
Radix Flemingiae Prostratae
New Source Material(s) added:
Flemingia prostrata - Root
NHPID Name:
Trimethyl Isopropyl Butanamide
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Fruit and Vegetable Blend
New Group organism(s) added:
Malus pumila
NHPID Name:
Fruit and Vegetable Blend
New Sub-ingredient(s) added:
Fiber
NHPID Name:
Fruit and Vegetable Fibre
New Group organism(s) added:
Daucus carota; Malus pumila; Spinacia oleracea; Vaccinium corymbosum
NHPID Name:
Fruit and Vegetable Fibre
Modification:
New Parts: Root fibre; Leaf fibre
NHPID Name:
Fruit and Vegetable Fibre
Method(s) of Preparation removed:
Dry; Powdered
NHPID Name:
Fruit and Vegetable Fibre
New Method(s) of Preparation added:
Extract dry; Extract dry standardized
NHPID Name:
Nobiletin
New Source Material(s) added:
Citrus depressa - Fruit peel
NHPID Name:
Lactoferrin
New Source Material(s) added:
Komagataella phaffii - Whole Cell for Biosynthesis
NHPID Name:
Folate
New Additional Details added :
The quantity of folate must always be provided in mcg of folic acid equivalents, irrespective of the source ingredient(s) used. Factors for converting mcg of dietary folate equivalents (DFEs) to mcg of supplemental folate have not been formally established by Health Canada; however, the quantity of folate can be provided in DFEs as additional information on the label using conversion factors established by other regulatory agencies. The conversion factors established by the United States Food and Nutrition Board and as outlined in the Codex nutrient reference values are as follows: 1 DFE = 1 mcg food folate; 1 DFE = 0.6 mcg folic acid from fortified food or from a supplement consumed with food (factor of 1.7); and 1 DFE = 0.5 mcg folic acid from a supplement taken on an empty stomach (factor of 2).
NHPID Name:
beta-Caryophyllene
CAS Registry Number(s) removed:
1407-53-0; 8007-38-3
NHPID Name:
beta-Caryophyllene
New Additional Details added :
beta-Caryophyllene is a sesquiterpenoid occurring in many essential oils, including that from the flowering tops of Cannabis sativa. As such, whether it is synthetic or not, the source information of beta-caryophyllene used as non-medicinal ingredient should also be provided in the web PLA form.
NHPID Name:
L-Leucine
New Source Ingredient(s) added:
Whey Protein Concentrate ; Whey Protein Isolate
NHPID Name:
L-Isoleucine
New Source Ingredient(s) added:
Whey Protein Concentrate ; Whey Protein Isolate
NHPID Name:
L-Valine
New Source Ingredient(s) added:
Whey Protein Concentrate ; Whey Protein Isolate
NHPID Name:
Whey Protein Concentrate
New Sub-ingredient(s) added:
L-Isoleucine ; L-Leucine ; L-Valine
NHPID Name:
Whey Protein Isolate
New Sub-ingredient(s) added:
L-Isoleucine ; L-Leucine ; L-Valine
NHPID Name:
Glycine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Alanine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Arginine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Aspartic acid
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Cystine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Glutamic acid
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Histidine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Lysine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Methionine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Phenylalanine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Proline
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Serine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Threonine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Tyrosine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Isoleucine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Leucine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
L-Valine
New Source Ingredient(s) added:
Whey Protein Hydrolysate
NHPID Name:
Whey Protein Hydrolysate
New Sub-ingredient(s) added:
Glycine; L-Alanine; L-Arginine; L-Aspartic acid; L-Cystine; L-Glutamic acid; L-Histidine; L-Lysine; L-Methionine; L-Phenylalanine; L-Proline; L-Serine; L-Threonine; L-Tyrosine; L-Isoleucine; L-Leucine; L-Valine
NHPID Name:
Copper (II) gluconate
New NMI Purpose(s):
Chelating Agent
NHPID Name:
Menaquinone 7
New Source Material(s) added:
Chickpea natto species (Parts: Whole Cell)
NHPID Name:
Vitamin K2
New Source Material(s) added:
Chickpea natto species (Parts: Whole Cell)
NHPID Name:
Sodium hyaluronate
New NMI Purpose(s):
Coating Agent ; Mucoadhesive
NHPID Name:
Bifidobacterium longum subsp. Longum
New Taxonomical Synonym(s) added:
Bifidobacterium longum
NHPID Name:
Calcium lactate gluconate
CAS Registry Number(s) removed:
11116-97-5
NHPID Name:
Calcium
New Source Ingredient(s) added:
Calcium lactate gluconate dihydrate
NHPID Name:
Protein
New Source Ingredient(s) added:
Ginseng Protein Hydrolysate
NHPID Name:
Panax ginseng
New Sub-ingredient(s) added:
Ginseng Protein Hydrolysate
NHPID Name:
Pollen Pini
New Source Material(s) added:
Pinus contorta (Parts: Pollen) ; Pinus massoniana (Parts: Pollen) ; Pinus ponderosa (Parts: Pollen)
NHPID Name:
Pollen Pini
New Additional Details added :
Pine pollen is described in the 2020 version of the Pharmacopoeia of the People's Republic of China (PPRC) as the dried pollen of Pinus massoniana Lamb., Pinus tabulaeformis Carr. or several other plants of the same genus (Fam. Pinaceae). As such, the pollen of Pinus species that are not specifically mentioned in PPRC (2020), such as Pinus ponderosa and Pinus contorta reported as being native to North America, may be comparable to the pollen of Pinus species reported as being native to China. Pinus ponderosa is also listed as being cultivated in the Flora of China (2025).
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
Modification:
Garlic
Modification:
Antioxidants
Modification:
Joint Health Products, Multiple Ingredient
Modification:
Fruit Bromelain/Stem Bromelain
Modification:
Turmeric - Oral
Modification:
Concentrated turmeric and isolates (curcuminoids/curcumin)
Modification:
Cod Liver Oil
Modification:
Fixed Oil Products - Oral
Modification:
Krill Oil
Modification:
Seal Oil
Modification:
Fish Oil
Modification:
Probiotics
Modification:
Calcium-Potassium Salt of Hydroxycitric Acid
Modification:
Malabar tamarind - Garcinia gummi-gutta
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
Modification:
New Dosage forms added: Capsule, enteric-coated; Capsule, soft, enteric-coated; Granule, enteric-coated; Tablet, enteric-coated
Modification:
New Test method added: GENE-UP(r) NUTRAPLEX(tm) PRO Real-Time PCR Assay
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
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