Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on November 29, 2024.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Macropiper Excelsum Leaf Extract

Role:
Non-medicinal


NHPID Name:
Larva Holotrichiae

Role:
Medicinal


NHPID Name:
Sideritis Scardica

Role:
Medicinal


NHPID Name:
Streptococcus Oralis Subsp. Dentisani

Role:
Medicinal


NHPID Name:
Soybean Peroxidase

Role:
Non-medicinal


NHPID Name:
Pericarpium Luffae Acutangulae

Role:
Medicinal


NHPID Name:
Saccharomyces/Artemisia Gmelinii Leaf/Stem/Agave Tequilana Stem Extract Ferment Filtrate

Role:
Non-medicinal


NHPID Name:
Hylocereus Costaricensis Fruit Powder

Role:
Non-medicinal


NHPID Name:
Capparis Spinosa (Caper) Fruit

Role:
Non-medicinal


NHPID Name:
Lactobacillus/Ganoderma Lucidum (Reishi Mushroom) Extract/Lentinus Edodes (Shiitake Mushroom) Extract Ferment Filtrate

Role:
Non-medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

No Changes.


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:
Sodium dodecyl diphenyloxide disulfonate

New NHPID Name:
Benzene, 1,1'-Oxybis-, Tetrapropylene Derivs., Sulfonated, Sodium Salts


Old NHPID Name:
Ammonium polyphosphate

New NHPID Name:
Ammonium Polyphosphate


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Benzene, 1,1'-Oxybis-, Tetrapropylene Derivs., Sulfonated, Sodium Salts

New Common Name(s):
Benzene, 1,1'-oxybis-, tetrapropylene derivs., sulfonated, sodium salts


NHPID Name:
Benzene, 1,1'-Oxybis-, Tetrapropylene Derivs., Sulfonated, Sodium Salts

Removed Common Name(s):
Sodium dodecyl diphenyloxide disulfonate


NHPID Name:
Chitosan

Removed Proper Name(s):
Poly-beta-(1,4)-2-amino-2-deoxy-d-glucose


NHPID Name:
Chitosan

New Proper Name(s):
Poly-beta-(1,4)-2-amino-2-deoxy-D-glucose


NHPID Name:
Chitosan

Removed Common Name(s):
Poly-D-glucosamine; Polyglucosamine


NHPID Name:
Myrosinase

Removed Proper Name(s):
Glucosidase, thio-


NHPID Name:
Myrosinase

New Proper Name(s):
Thioglucoside glucohydrolase


NHPID Name:
Sodium Polyphosphate

Removed Proper Name(s):
Sodium Polyphosphate


NHPID Name:
Sodium Polyphosphate

New Proper Name(s):
Polyphosphoric acids, sodium salts


NHPID Name:
Sodium Polyphosphates, Glassy

Removed Proper Name(s):
Polyphosphoric acids, sodium salts; Sodium polyphosphate; Sodium tetrapolyphosphate


NHPID Name:
Sodium Polyphosphates, Glassy

New Proper Name(s):
Sodium polyphosphates, glassy


NHPID Name:
Ammonium polyphosphate

Removed Common Name(s):
Ammonium polyphosphate


NHPID Name:
Ammonium polyphosphate

New Common Name(s):
Ammonium polyphosphate


NHPID Name:
Ammonium polyphosphate

Removed Proper Name(s):
Polyphosphoric acids, ammonium salt


NHPID Name:
Ammonium polyphosphate

New Proper Name(s):
Polyphosphoric acids, ammonium salts


NHPID Name:
Calcium polyphosphate

Removed Proper Name(s):
Calcium polyphosphate


NHPID Name:
Calcium polyphosphate

New Proper Name(s):
Polyphosphoric acids, calcium salts


NHPID Name:
Potassium Polyphosphate

Removed Proper Name(s):
Potassium polyphosphate


NHPID Name:
Potassium Polyphosphate

New Proper Name(s):
Polyphosphoric acids, potassium salts


NHPID Name:
Sodium Calcium Polyphosphate

Removed Proper Name(s):
Sodium calcium polyphosphate


NHPID Name:
Sodium Calcium Polyphosphate

New Proper Name(s):
Polyphosphoric acids, sodium calcium salts


NHPID Name:
Glycyrrhiza inflata

New Common Name(s):
Chinese licorice


NHPID Name:
Pollen Pini

Removed Proper Name(s):
Pinus contorta; Pinus ponderosa


NHPID Name:
Spinosad

Removed Proper Name(s):
Spinosad


NHPID Name:
Spinosad

New Proper Name(s):
Spinosyn A and D isoforms


NHPID Name:
Terminalia bellirica

Removed Common Name(s):
Beleric myrobalan; Belleric myrobalan; Bohera; Myrobalan


NHPID Name:
Terminalia bellirica

New Common Name(s):
Beleric myrobalan; Belleric myrobalan; Bahera; Myrobalan


NHPID Name:
Phyllanthus emblica

Removed Common Name(s):
Emblic; Emblic myrobalan


NHPID Name:
Phyllanthus emblica

New Common Name(s):
Emblic; Emblic myrobalan


NHPID Name:
Hypromellose

Removed Common Name(s):
Carbohydrate gum


NHPID Name:
Hypromellose

New Common Name(s):
Carbohydrate gum


NHPID Name:
l-Carvone

New Common Name(s):
Carvone


NHPID Name:
d-Carvone

Removed Proper Name(s):
d-Carvone


NHPID Name:
d-Carvone

New Common Name(s):
Carvone


NHPID Name:
d-Carvone

New Proper Name(s):
d-1-Methyl-4-isopropenyl-6-cyclohexen-2-one


NHPID Name:
dl-Menthol

New Common Name(s):
Menthol


NHPID Name:
d-Menthol

New Common Name(s):
Menthol


NHPID Name:
beta-Pinene

New Common Name(s):
Pinene


NHPID Name:
alpha-Pinene

Removed Common Name(s):
DL-Pin-2(3)-ene


NHPID Name:
trans-Anethole

New Common Name(s):
Anethole


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
Luteolin

Old Role:
Medicinal

New Role:
Medicinal & Non-medicinal


NHPID Name:
Spinosad

Old Role:
Medicinal

New Role:
Non-NHP


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Medicago Sativa (Alfalfa) Extract

New Non-medicinal Restriction(s) added:
For topical use only.


NHPID Name:
Sodium Polyphosphate

New Non-medicinal Restriction(s) added:
When formulated to be non-irritating.


NHPID Name:
Sodium Polyphosphates, Glassy

New Route(s) of Adminstration added:
Oral


NHPID Name:
Ammonium Polyphosphate

New Route(s) of Adminstration added:
Oral


NHPID Name:
Calcium Polyphosphate

New Route(s) of Adminstration added:
Oral


NHPID Name:
Potassium Polyphosphate

New Route(s) of Adminstration added:
Oral


NHPID Name:
Sodium Calcium Polyphosphate

Non-medicinal Restriction(s) removed:
Maximum Tolerable Intake: up to 70 mg/kg body weight daily for phosphorus from all sources, expressed as P. (JECFA 1985). Must be declared as a medicinal ingredient in mineral products at doses of 125 mg/d P or Ca.


NHPID Name:
Asiaticoside

New Non-medicinal Restriction(s) added:
For topical use only.


NHPID Name:
Hypromellose

New Non-medicinal Restriction(s) added:
Route Of administration:Topical; Allowed purposes:Adhesive , Binder , Emulsion Stabilizer , Film Former , Stabilizing Agent , Thickening Agent , Viscosity Increasing Agent , Viscosity Increasing Agent - Aqueous; Detail:Up to 36%.


NHPID Name:
Hypromellose

New Non-medicinal Restriction(s) added:
Route Of administration:Ophthalmic; Allowed purposes:Thickening Agent; Detail:At concentrations below 0.2%.


NHPID Name:
Hypromellose

New Non-medicinal Restriction(s) added:
Route Of administration:Oral; Allowed purposes:Adhesive , Binder , Coating Agent , Controlled Release Vehicle , Dispersing Agent , Dissolution Enhancing Agent , Encapsulating Agent , Film Former , Stabilizing Agent , Thickening Agent


NHPID Name:
d-Carvone

New Non-medicinal Restriction(s) added:
For the purpose of flavour enhancer, in topical products which may result in incidental ingestion, such as lipsticks.


NHPID Name:
PEG-7 Trimethylolpropane Coconut Ether

New Non-medicinal Restriction(s) added:
For topical use only.


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Luteolin

New NMI Purpose(s):
Colour Additive


NHPID Name:
Astaxanthin

New Source Material(s) added:
Haematococcus pluvialis (Parts: Broken cell)


NHPID Name:
Haematococcus pluvialis

New Sub-ingredient(s) added:
Astaxanthin


NHPID Name:
Chitosan

Source Material(s) removed:
Crab (Parts: Shell); Krill (Parts: Shell); Shrimp (Parts: Shell)


NHPID Name:
Chitosan

New Source Material(s) added:
Crab (Parts: Exoskeleton); Krill (Parts: Exoskeleton); Shrimp (Parts: Exoskeleton)


NHPID Name:
Chitosan

Source Ingredient(s) removed:
Chitin


NHPID Name:
Chitin

Sub-ingredient(s) removed:
Chitosan


NHPID Name:
Chitin

Source Material(s) removed:
Crab (Parts: Shell); Krill (Parts: Shell); Shrimp (Parts: Shell); Squid (Parts: Shell)


NHPID Name:
Chitin

New Source Material(s) added:
Crab (Parts: Exoskeleton); Krill (Parts: Exoskeleton); Shrimp (Parts: Exoskeleton); Squid (Parts: Internal shell)


NHPID Name:
Myrosinase

New Source Material(s) added:
Sinapis alba (Parts: Seed)


NHPID Name:
Sinapis alba

New Sub-ingredient(s) added:
Myrosinase


NHPID Name:
Medicago Sativa (Alfalfa) Extract

Modification:
Removed Schedule 1: Extract


NHPID Name:
Medicago Sativa (Alfalfa) Extract

Method(s) of Preparation removed:
Extract dry standardized , Extract liquid standardized


NHPID Name:
Medicago Sativa (Alfalfa) Extract

Removed NMI purpose(s):
Colour Additive , Flavour Enhancer


NHPID Name:
Medicago Sativa (Alfalfa) Extract

New NMI Purpose(s):
Skin-Conditioning Agent - Emollient , Skin-Conditioning Agent - Humectant


NHPID Name:
Sodium Polyphosphate

New CAS Registry Number(s) added:
68915-31-1


NHPID Name:
Sodium Polyphosphate

New Toxicity restriction added:
Upper limit:70.0; Units:Milligrams/kilogram body weight/day; Detail:Group maximum tolerable daily intake up to 70 mg/kg bw/day, expressed as phosphorus.


NHPID Name:
Sodium Polyphosphate

New NMI Purpose(s):
Emulsifying Agent , Stabilizing Agent


NHPID Name:
Sodium Polyphosphates, Glassy

New Toxicity restriction added:
Upper limit:70.0; Units:Milligrams/kilogram body weight/day; Detail:Group maximum tolerable daily intake up to 70 mg/kg bw/day, expressed as phosphorus.


NHPID Name:
Ammonium Polyphosphate

New Toxicity restriction added:
Upper limit:70.0; Units:Milligrams/kilogram body weight/day; Detail:Group maximum tolerable daily intake up to 70 mg/kg bw/day, expressed as phosphorus.


NHPID Name:
Calcium Polyphosphate

New Toxicity restriction added:
Upper limit:70.0; Units:Milligrams/kilogram body weight/day; Detail:Group maximum tolerable daily intake up to 70 mg/kg bw/day, expressed as phosphorus.


NHPID Name:
Potassium Polyphosphate

New Toxicity restriction added:
Upper limit:70.0; Units:Milligrams/kilogram body weight/day; Detail:Group maximum tolerable daily intake up to 70 mg/kg bw/day, expressed as phosphorus.


NHPID Name:
Sodium Calcium Polyphosphate

CAS Registry Number(s) removed:
65997-17-3


NHPID Name:
Sodium Calcium Polyphosphate

New Toxicity restriction added:
Upper limit:70.0; Units:Milligrams/kilogram body weight/day; Detail:Group maximum tolerable daily intake up to 70 mg/kg bw/day, expressed as phosphorus.


NHPID Name:
Sodium Calcium Polyphosphate

Removed NMI purpose(s):
Emulsion Stabilizer


NHPID Name:
Sodium Calcium Polyphosphate

New NMI Purpose(s):
Stabilizing Agent


NHPID Name:
Glycyrrhizin

New Source Material(s) added:
Glycyrrhiza glabra (Parts: Root and rhizome); Glycyrrhiza glabra (Parts: Root and rhizome and stolon); Glycyrrhiza inflata (Parts: Root); Glycyrrhiza inflata (Parts: Root and rhizome); Glycyrrhiza uralensis (Parts: Root and rhizome)


NHPID Name:
Glycyrrhiza glabra

New Sub-ingredient(s) added:
Glycyrrhizin


NHPID Name:
Glycyrrhiza inflata

New Sub-ingredient(s) added:
Glycyrrhizin


NHPID Name:
Glycyrrhiza uralensis

New Sub-ingredient(s) added:
Glycyrrhizin


NHPID Name:
Pollen Pini

Source Material(s) removed:
Pinus contorta (Parts: Pollen); Pinus ponderosa (Parts: Pollen)


NHPID Name:
Pollen Pini

New Method(s) of Preparation added:
Decoction concentrate


NHPID Name:
Spinosad

Modification:
Removed Schedule 1:Isolate


NHPID Name:
Rosmarinic acid

New Source Material(s) added:
Salvia officinalis (Parts: Leaf)


NHPID Name:
Salvia officinalis

New Sub-ingredient(s) added:
Rosmarinic acid


NHPID Name:
Glycine max

New Sub-ingredient(s) added:
Soybean Peroxidase


NHPID Name:
Asiaticoside

New Source Material(s) added:
Centella asiatica (Parts: Herb top)


NHPID Name:
Centella asiatica

New Sub-ingredient(s) added:
Asiaticoside


NHPID Name:
Hypromellose

Removed NMI purpose(s):
Diluent; Disintegrant; Gelling Agent; Lubricant


NHPID Name:
d-Carvone

Toxicity Restriction removed:
Flavouring agent only Acceptable daily intake up to 1 mg/kg body weight (JECFA 1998);


NHPID Name:
d-Carvone

New NMI Purpose(s):
Fragrance Ingredient


NHPID Name:
PEG-7 Trimethylolpropane Coconut Ether

New NMI Purpose(s):
Surfactant - Emulsifying Agent


NHPID Name:
PEG-7 Trimethylolpropane Coconut Ether

Removed NMI purpose(s):
Emulsifying Agent , Surfactant


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

Modification:
Goldenseal - Oral


Modification:
Witch Hazel - Hamamelis Virginiana Oral


Modification:
Virginiana Oral


Modification:
Antioxidants


Modification:
Black Walnut - Juglans nigra


Modification:
Fennel, Bitter


Modification:
Chitosan


Modification:
Cognitive function products


Modification:
Dandelion - Taraxacum officinale


Modification:
Ginseng, American


Modification:
Alfalfa


Modification:
Black Pepper - Piper nigrum


Modification:
Triphala


Modification:
Licorice


Modification:
Whey Products


Modification:
Skullcap - Scutellaria Lateriflora


Modification:
Sweet Fennel - Foeniculum Vulgare


Modification:
Workout Supplements


Modification:
Passionflower - Passiflora Incarnata


Modification:
Marshmallow - Althaea Officinalis - Leaf


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

NHPID Name:
HPUS_Anacardium orientale

Modification:
Removed Source material(s): Juice from the layer between the husk and kernel of the fruit; Jus de la couche entre l'enveloppe et le noyau du fruit


NHPID Name:
HPUS_Anacardium orientale

Modification:
New Source material(s): Dried fruit; Fruit séché


NHPID Name:
HPUS_Anacardium orientale

Modification:
Minimum homeopathic potency: 4X

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