Chemical Substance - Folate

NHPID name:
Folate

Reference:

Proper name(s):

Common name(s):

Category:
Approved Chemical Name
Monograph(s):

Schedule 1:


Source material:

Source ingredients:


Additional details:

Detail:
The quantity of folate must always be provided in mcg of folic acid equivalents, irrespective of the source ingredient(s) used. Factors for converting mcg of dietary folate equivalents (DFEs) to mcg of supplemental folate have not been formally established by Health Canada; however, the quantity of folate can be provided in DFEs as additional information on the label using conversion factors established by other regulatory agencies. The conversion factors established by the United States Food and Nutrition Board and as outlined in the Codex nutrient reference values are as follows: 1 DFE = 1 mcg food folate; 1 DFE = 0.6 mcg folic acid from fortified food or from a supplement consumed with food (factor of 1.7); and 1 DFE = 0.5 mcg folic acid from a supplement taken on an empty stomach (factor of 2).


Roles

Medicinal

Rationale:

Classified as an NHP under Schedule 1, item 3 (a vitamin) of the Natural Health Products Regulations.

Reference:  NNHPD
Restrictions:

Daily Dose

Upper limit:
1.0

Units:

Route Of administration:

Detail:
< 1mg/day of folic acid as per the Prescription Drug List

Reference:
PDL


Non-NHP

Rationale:

As per the Prescription Drug List, the dose of Folic acid in oral NHPs must not exceed 1 mg/day, and above 1 mg/day, Folic acid is classified as a non-NHP.

Reference:  NNHPD
Date modified: