Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the
last update. This page was most recently revised on May 13, 2022.
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
Lemongrass Oil
Role:
Non-medicinal
NHPID Name:
Rhododendron Ferrugineum Extract
Role:
Non-medicinal
NHPID Name:
Miliacin
Role:
Component
NHPID Name:
Tasmannia Lanceolata Fruit/Leaf Extract
Role:
Non-medicinal
NHPID Name:
Lycium Barbarum Seed Oil
Role:
Non-medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
NHPID Name:
Magnesium bisglycinate
Role:
No role
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Cymbopogon Flexuosus Oil
New NHPID Name:
Cymbopogon Flexuosus Oil
Old NHPID Name:
Leucine hydrochloride
New NHPID Name:
L-Leucine hydrochloride
Old NHPID Name:
N-Acetylleucine
New NHPID Name:
N-Acetyl-L-leucine
Old NHPID Name:
Lysine acetate
New NHPID Name:
L-Lysine acetate
Old NHPID Name:
Lysine dihydrochloride
New NHPID Name:
L-Lysine dihydrochloride
Old NHPID Name:
Tryptophan
New NHPID Name:
L-Tryptophan
Old NHPID Name:
1,5,5,9-Tetramethyl-13-oxatricyclo[8.3.0.0.(4.9)]tridecane
New NHPID Name:
Amberlyn
Old NHPID Name:
Caffeoylquinic acids
New NHPID Name:
Caffeoylquinic acids
Old NHPID Name:
Neohesperidin dihydrochalcone
New NHPID Name:
Neohesperidin Dihydrochalcone
NHPID Name:
Cymbopogon Flexuosus Oil
Removed Common Name(s):
Cymbopogon Flexuosus Essential Oil
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
Cymbopogon Flexuosus Oil
New Common Name(s):
Cymbopogon flexuosus oil
NHPID Name:
L-Histidine hydrochloride
Removed Common Name(s):
L-Histidine monohydrochloride
NHPID Name:
L-Histidine hydrochloride
New Common Name(s):
L-Histidine monohydrochloride
NHPID Name:
L-Lysine-L-aspartate
New Common Name(s):
L-Lysine-L-aspartate
NHPID Name:
L-Lysine monohydrochloride
Removed Proper Name(s):
(S)-2,6-Diaminohexanoic monohydrochloride
NHPID Name:
L-Lysine monohydrochloride
New Proper Name(s):
L-Lysine monohydrochloride
NHPID Name:
L-Lysine acetate
Removed Proper Name(s):
L-2,6-Diaminohexanoic acid acetate
NHPID Name:
L-Lysine acetate
New Proper Name(s):
L-2,6-Diaminohexanoic acid acetate
NHPID Name:
L-Lysine dihydrochloride
New Common Name(s):
L-Lysine dihydrochloride
NHPID Name:
Ginkgo Biloba Leaf Extract
Removed Common Name(s):
Ginkgo Extract; Maidenhair Extract; Ginkgo Biloba
NHPID Name:
Amberlyn
New Common Name(s):
Amberlyn
NHPID Name:
Amberlyn
Removed Common Name(s):
1,5,5,9-Tetramethyl-13-oxatricyclo[8.3.0.0.(4.9)]tridecane
NHPID Name:
Caffeoylquinic acids
New Common Name(s):
Caffeoylquinic acids
NHPID Name:
Caffeoylquinic acids
New Proper Name(s):
Caffeoylquinic acids
NHPID Name:
Caffeoylquinic acids
Removed Common Name(s):
Caffeoylquinic acids
NHPID Name:
Caffeoylquinic acids
Removed Proper Name(s):
Caffeoylquinic acids
NHPID Name:
Neohesperidin Dihydrochalcone
Removed Common Name(s):
Neohesperidin dihydrochalcone
NHPID Name:
Neohesperidin Dihydrochalcone
New Common Name(s):
Neohesperidin dihydrochalcone
NHPID Name:
East Indian Lemongrass Essential Oil
Old Role:
Medicinal & Non-medicinal
NHPID Name:
N-Acetyl-L-leucine
Old Role:
Medicinal
NHPID Name:
N-Glycyl-L-leucine
Old Role:
Medicinal
NHPID Name:
L-Lysine acetate
Old Role:
Medicinal
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
NHPID Name:
N-Acetyl-L-methionine
Old Role:
Medicinal
New Role:
No role
NHPID Name:
DL-Phenylalanine
Old Role:
Medicinal
New Role:
No role
NHPID Name:
Cymbopogon Flexuosus Oil
New Non-medicinal Restriction(s) added:
For topical use only, up to 0.7%.
NHPID Name:
Cymbopogon Flexuosus Oil
Restriction Reference removed:
CosIng
NHPID Name:
Cymbopogon Flexuosus Oil
New Restriction Reference added:
EQSAFTY2
NHPID Name:
Durapatite
Non-medicinal Restriction(s) removed:
For topical use only.
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Durapatite
New Non-medicinal Restriction(s) added:
General
NHPID Name:
L-Histidine
New Non-medicinal Restriction(s) added:
Up to 0.05%.
NHPID Name:
L-Histidine
Restriction Reference removed:
ICID
NHPID Name:
L-Histidine
New Restriction Reference added:
CIR
NHPID Name:
L-Histidine hydrochloride
New Non-medicinal Restriction(s) added:
For topical use only, up to 0.07%.
NHPID Name:
L-Histidine hydrochloride
Restriction Reference removed:
ICID
NHPID Name:
L-Histidine hydrochloride
New Restriction Reference added:
CIR
NHPID Name:
L-Isoleucine
New Route(s) of Adminstration added:
Oral
NHPID Name:
L-Isoleucine
Restriction Reference removed:
UNAVA
NHPID Name:
L-Isoleucine
New Restriction Reference added:
WHO_JECFA
NHPID Name:
L-Isoleucine
New Non-medicinal Restriction(s) added:
General
NHPID Name:
L-Leucine
New Route(s) of Adminstration added:
Oral
NHPID Name:
L-Leucine
Restriction Reference removed:
UNAVA
NHPID Name:
L-Leucine
New Restriction Reference added:
HPE_2009
NHPID Name:
L-Leucine
New Non-medicinal Restriction(s) added:
General
NHPID Name:
L-Lysine
New Restriction Reference added:
Oral
NHPID Name:
L-Lysine
New Non-medicinal Restriction(s) added:
General; General
NHPID Name:
L-Lysine
Restriction Reference removed:
UNAVA
NHPID Name:
L-Lysine
New Restriction Reference added:
Appl_Micro_Biot_92(609)
NHPID Name:
L-Lysine monohydrochloride
New Non-medicinal Restriction(s) added:
Up to 0.6%.
NHPID Name:
L-Lysine monohydrochloride
Restriction Reference removed:
ICID
NHPID Name:
L-Lysine monohydrochloride
New Restriction Reference added:
CIR
NHPID Name:
L-Methionine
New Route(s) of Adminstration added:
Oral
NHPID Name:
L-Methionine
Restriction Reference removed:
UNAVA
NHPID Name:
L-Methionine
New Restriction Reference added:
HPE_2009
NHPID Name:
L-Phenylalanine
New Route(s) of Adminstration added:
Oral
NHPID Name:
L-Phenylalanine
Restriction Reference removed:
UNAVA
NHPID Name:
L-Phenylalanine
New Restriction Reference added:
FHFI_2010
NHPID Name:
L-Phenylalanine
New Non-medicinal Restriction(s) added:
General
NHPID Name:
L-Threonine
New Route(s) of Adminstration added:
Oral
NHPID Name:
L-Threonine
Restriction Reference removed:
UNAVA
NHPID Name:
L-Threonine
New Restriction Reference added:
NNHPD
NHPID Name:
L-Threonine
New Non-medicinal Restriction(s) added:
General
NHPID Name:
DL-Threonine
New Route(s) of Adminstration added:
Oral
NHPID Name:
DL-Threonine
Restriction Reference removed:
UNAVA
NHPID Name:
DL-Threonine
New Restriction Reference added:
Appl_Micro_Biot_92(609)
NHPID Name:
L-Tryptophan
New Route(s) of Adminstration added:
Oral
NHPID Name:
L-Tryptophan
New Non-medicinal Restriction(s) added:
General
NHPID Name:
L-Tryptophan
Restriction Reference removed:
HCSF; UNAVA
NHPID Name:
L-Tryptophan
New Restriction Reference added:
PDL; EUR_J_PH_BIOPH
NHPID Name:
L-Valine
New Route(s) of Adminstration added:
Oral
NHPID Name:
L-Valine
New Non-medicinal Restriction(s) added:
General
NHPID Name:
L-Valine
Restriction Reference removed:
UNAVA
NHPID Name:
L-Valine
New Restriction Reference added:
NNHPD
NHPID Name:
Ginkgo Biloba Leaf Extract
New Non-medicinal Restriction(s) added:
For topical use only, up to 0.25%, when formulated to be non-sensitizing.
NHPID Name:
Ginkgo Biloba Leaf Extract
Restriction Reference removed:
ICID
NHPID Name:
Ginkgo Biloba Leaf Extract
New Restriction Reference added:
CIR
NHPID Name:
Amberlyn
New Non-medicinal Restriction(s) added:
For oral use only.
NHPID Name:
Amberlyn
Restriction Reference removed:
JECFA
NHPID Name:
Amberlyn
New Restriction Reference added:
WHO_JECFA
NHPID Name:
Phellodendron Amurense Bark Extract
New Non-medicinal Restriction(s) added:
For topical use only.
NHPID Name:
Neohesperidin Dihydrochalcone
New Non-medicinal Restriction(s) added:
For buccal or oral use only.
NHPID Name:
Neohesperidin Dihydrochalcone
Restriction Reference removed:
UNAVA
NHPID Name:
Neohesperidin Dihydrochalcone
New Restriction Reference added:
HPE_2009
NHPID Name:
Cymbopogon Flexuosus Oil
Modification:
Removed Schedule 1: Extract
NHPID Name:
Cymbopogon Flexuosus Oil
Method(s) of Preparation removed:
Oil, Essential (water steam distillation) Standardized
NHPID Name:
Cymbopogon Flexuosus Oil
Removed NMI purpose(s):
Masking Agent
NHPID Name:
Cymbopogon Flexuosus Oil
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
L-Leucine
Removed NMI purpose(s):
Fragrance Ingredient
NHPID Name:
L-Leucine hydrochloride
Name Reference removed:
MI; NNHPD; MI; NNHPD
NHPID Name:
L-Leucine hydrochloride
New Name Reference added:
CHEMID; CHEMID; CHEMID; CHEMID
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
N-Acetyl-L-leucine
Name Reference removed:
DNP
NHPID Name:
N-Acetyl-L-leucine
New Name Reference added:
CHEMID
NHPID Name:
N-Acetyl-L-leucine
Modification:
Removed Schedule 1: Isolate
NHPID Name:
N-Glycyl-L-leucine
Modification:
Removed Schedule 1:Isolate
NHPID Name:
L-Lysine monohydrochloride
Name Reference removed:
MI; MI
NHPID Name:
L-Lysine monohydrochloride
New Name Reference added:
CHEMID; CHEMID
NHPID Name:
L-Lysine acetate
Modification:
Removed Schedule 1:Isolate
NHPID Name:
L-Lysine acetate
Name Reference removed:
USP_31; MARO
NHPID Name:
L-Lysine acetate
New Name Reference added:
PUBCHEM; CHEMID
NHPID Name:
L-Lysine dihydrochloride
Name Reference removed:
EPA; EPA
NHPID Name:
L-Lysine dihydrochloride
New Name Reference added:
CHEMID; CHEMID
NHPID Name:
L-Methionine
New Name Reference added:
MIO; MIO; MIO
NHPID Name:
L-Methionine
Name Reference removed:
NMCD; NMCD; NMCD
NHPID Name:
N-Acetyl-L-methionine
Modification:
Removed Schedule 1:Isolate
NHPID Name:
Calcium
New Source Material(s) added:
Hyriopsis cumingii (Parts: Pearl)
NHPID Name:
Hyriopsis cumingii
New Sub-ingredient(s) added:
Calcium
NHPID Name:
Hyriopsis cumingii
Modification:
New Source Material Constituent(s):
Pearl
NHPID Name:
Panicum miliaceum
Modification:
New Source Material
Constituent(s):
Seed
NHPID Name:
Panicum miliaceum
New Sub-ingredient(s) added:
Miliacin
NHPID Name:
Ginkgo Biloba Leaf Extract
Modification:
Removed Schedule 1:Extract
NHPID Name:
Ginkgo Biloba Leaf Extract
Method(s) of Preparation removed:
Extract liquid standardized; Extract dry standardized
NHPID Name:
Amberlyn
New Name Reference added:
CHEMID; WHO_JECFA
NHPID Name:
Amberlyn
Name Reference removed:
EC-FL; EC-FL
NHPID Name:
Phellodendron Amurense Bark Extract
Modification:
Removed Schedule 1: Plant and plant material
NHPID Name:
Phellodendron Amurense Bark Extract
Source Material(s) removed:
Phellodendron amurense
( Parts: Stem bark )
NHPID Name:
Phellodendron Amurense Bark Extract
New Source Material(s) added:
Phellodendron amurense
( Parts: Bark )
NHPID Name:
Phellodendron Amurense Bark Extract
Method(s) of Preparation removed:
Dry; Extract dry standardized; Extract liquid standardized; Powdered
NHPID Name:
Caffeoylquinic acids
Modification:
Revised Category: Herbal Component Name
NHPID Name:
Caffeoylquinic acids
New Source Material(s) added:
Cynara cardunculus ( Parts: Flower bud )
NHPID Name:
Cynara cardunculus
Name Reference removed:
UNAVA
NHPID Name:
Cynara cardunculus
New Name Reference added:
GRIN
NHPID Name:
Cynara cardunculus
New Sub-ingredient(s) added:
Caffeoylquinic acids
NHPID Name:
Cynara cardunculus
Modification:
Source Material
Constituent(s):
Flower bud
NHPID Name:
Eugenol
New Source Material(s) added:
Ocimum tenuiflorum ( Parts: Leaf )
NHPID Name:
Ocimum tenuiflorum
Modification:
New Source Material
Constituent(s):Leaf
NHPID Name:
Ocimum tenuiflorum
New Sub-ingredient(s) added:
Eugenol
NHPID Name:
Bombyx mori
Method(s) of Preparation removed:
Live
NHPID Name:
Bombyx mori
New Method(s) of Preparation added:
Dry , Fresh
NHPID Name:
Bombyx mori
New Name Reference added:
ITIS
NHPID Name:
Bombyx mori
Name Reference removed:
UNAVA
NHPID Name:
Neohesperidin Dihydrochalcone
New Toxicity restriction added:
Acceptable daily intake up to 5 mg/kg bw/day.
Old NHPID Name:
Magnesium glycinate
New NHPID Name:
Magnesium bisglycinate
NHPID Name:
Magnesium bisglycinate
Removed Proper Name(s):
Magnesium diglycinate
NHPID Name:
Magnesium bisglycinate
Removed Common Name(s):
Magnesium bisglycinate
NHPID Name:
Magnesium bisglycinate
New Common Name(s):
Magnesium bisglycinate
NHPID Name:
Magnesium bisglycinate
New Sub-ingredient(s) added:
Glycine
NHPID Name:
Magnesium bisglycinate
Route(s) of Adminstration removed:
Oral
NHPID Name:
Magnesium bisglycinate
Restriction Reference removed:
CHEMID
NHPID Name:
Magnesium bisglycinate
New Restriction Reference added:
EFSA
NHPID Name:
Magnesium bisglycinate
Name Reference removed:
CHEMID
NHPID Name:
Magnesium bisglycinate
New Name Reference added:
EFSA
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
No Changes.
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
No Changes.
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
RemIng
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