Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on March 25, 2022.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Aloe Barbadensis Leaf

Role:
Non-Medicinal


NHPID Name:
Aloe Barbadensis Leaf Polysaccharides

Role:
Non-Medicinal


NHPID Name:
Sodium Polyaspartate

Role:
Non-Medicinal


NHPID Name:
Krill Protein Hydrolysate

Role:
Medicinal


NHPID Name:
Belladonnae Extractum

Role:
Medicinal


NHPID Name:
Magnesium Monoperoxyphthalate Hexahydrate

Role:
No role


NHPID Name:
Caraway Oil

Role:
Non-Medicinal


NHPID Name:
Carum Carvi (Caraway) Fruit Oil

Role:
Non-Medicinal


NHPID Name:
Pentaerythrityl Tetrabehenate

New Proper Name(s):
2,2-Bis[[(1-oxodocosyl)oxy]methyl]-1,3-propanediyl docosanoate


NHPID Name:
Pentaerythrityl Tetrabehenate

Removed Proper Name(s):
Pentaerythrityl tetrabehenate


NHPID Name:
Pentaerythrityl Tetracaprylate/Tetracaprate

New Proper Name(s):
Decanoic acid, mixed esters with octanoic acid and pentaerythritol


NHPID Name:
Pentaerythrityl Tetracaprylate/Tetracaprate

Removed Proper Name(s):
Pentaerythrityl Tetracaprylate/Tetracaprate


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

No Changes.


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

No Changes.


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Pancreatic Extract

Removed Proper Name(s):
Bos taurus


NHPID Name:
Magnesium Monoperoxyphthalate

New Proper Name(s):
(T-4)-Bis[2-carboxybenzenecarboperoxoato(2?)-kappaOO,kappaO']magne?sate(2?) hydrogen (1:2)


NHPID Name:
Magnesium Monoperoxyphthalate

Removed Common Name(s):
Dihydrogen bis(monoperoxyphthalato(2-)-O1,OO1)magnesate(2-)


NHPID Name:
Magnesium Monoperoxyphthalate

New Common Name(s):
Magnesium monoperoxyphthalate


NHPID Name:
Pentaerythritol Rosinate

Old Role:
Non-Medicinal


NHPID Name:
Pancreatic Enzymes

Old Role:
No role


NHPID Name:
Pancreatic Extract

Old Role:
No role


NHPID Name:
Pancreatin

Old Role:
No role


NHPID Name:
Pancreatin

Old Role:
No role


NHPID Name:
Pancrelipase

Old Role:
No role


NHPID Name:
Pancrelipase

Old Role:
No role


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
Caraway Essential Oil

Old Role:
Non-Medicinal

New Role:
No role


NHPID Name:
Dicocoyl Pentaerythrityl Distearyl Citrate

Non-medicinal Restriction(s) changed:
New Detail: For topical use only.



NHPID Name:
Dipentaerythrityl Hexa C5-9 Acid Esters

Non-medicinal Restriction(s) changed:
New Detail: For topical use only.



NHPID Name:
Dipentaerythrityl Pentaisononanoate

Non-medicinal Restriction(s) changed:
New Detail: For topical use only, up to 13%.



NHPID Name:
Dipentaerythrityl Tri-Polyhydroxystearate

New Source Material(s) added:
New Detail: For topical use only.



NHPID Name:
PEG-150 Pentaerythrityl Tetrastearate

New Source Material(s) added:
New Detail: For topical use only, up to 5% in rinse-off products and up to 1.8% in leave-on products.



NHPID Name:
Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate

New Route(s) of Adminstration added:
Topical



NHPID Name:
Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate

Non-medicinal Restriction(s) changed:
New Detail: For topical use only, up to 0.8%.



Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Pentaerythrityl Tetrabehenate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Pentaerythrityl Tetrabehenate

Non-medicinal Restriction(s) changed:
New Detail: For topical use only, up to 3%.


NHPID Name:
Pentaerythrityl Tetracaprylate/Tetracaprate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Pentaerythrityl Tetracaprylate/Tetracaprate

Non-medicinal Restriction(s) changed:
New Detail: For topical use only, up to 5%.


NHPID Name:
Pentaerythrityl Tetraethylhexanoate

Non-medicinal Restriction(s) changed:
Revised Detail: For topical use only, up to 50%.


NHPID Name:
Pentaerythrityl Tetraisostearate

Non-medicinal Restriction(s) changed:
Revised Detail: For topical use only, up to 55%.


NHPID Name:
Pancreatic Enzymes

Non-medicinal Restriction(s) changed:
Revised Detail: The maximum dose of pancreatic enzymes, in terms of lipase activity, is 20 000 USP units per dosage unit.


NHPID Name:
Pancreatic Extract

Non-medicinal Restriction(s) changed:
Revised Detail: The maximum dose of pancreatic extract, in terms of lipase activity, is 20 000 USP units per dosage unit.


NHPID Name:
Fruit and Vegetable Blend (NMI)

Non-medicinal Restriction(s) changed:
Revised Detail: The blend may not include components that have been identified by Health Canada as priority food allergens; for example, mustard, peanuts, sesame, soy, any tree nuts, or wheat and other cereal grains containing gluten.


NHPID Name:
Fruit Blend (NMI)

Non-medicinal Restriction(s) removed:
General


NHPID Name:
Fruit Blend (NMI)

Non-medicinal Restriction(s) changed:
Revised Detail: The blend may not include components that have been identified by Health Canada as priority food allergens; for example, mustard, peanuts, sesame, soy, any tree nuts, or wheat and other cereal grains containing gluten.


NHPID Name:
Oleoresin Caraway

New Route(s) of Adminstration added:
Oral


NHPID Name:
Oleoresin Caraway

Non-medicinal Restriction(s) changed:
Removed Allowed Purposes: Flavour Enhancer; Revised Detail: For oral use only.


NHPID Name:
Dipentaerythrityl Pentaisononanoate

Toxicity Restriction removed:
Route Of Administration: Topical


NHPID Name:
PEG-150 Pentaerythrityl Tetrastearate

New CAS Registry Number(s) added:
130249-48-8


NHPID Name:
PEG-150 Pentaerythrityl Tetrastearate

Modification:
Revised Purposes: Surfactant - Emulsifying Agent


NHPID Name:
Pentaerythrityl Tetrabehenate

New CAS Registry Number(s) added:
61682-73-3


NHPID Name:
Pentaerythrityl Tetracaprylate/Tetracaprate

New CAS Registry Number(s) added:
68441-68-9


NHPID Name:
Euphausia superba

New Sub-ingredient(s) added:
Krill Protein Hydrolysate


NHPID Name:
Protein

New Source Ingredient(s) added:
Krill Protein Hydrolysate


NHPID Name:
Extractum Liquidum Belladonae

Method(s) of Preparation removed:
Extract dry; Extract dry standardized


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Pancreatic Enzymes

Modification:
Revised Schedule 1: Extract


NHPID Name:
Pancreatic Enzymes

Method(s) of Preparation removed:
Dry standardized


NHPID Name:
Pancreatic Enzymes

New Method(s) of Preparation added:
Extract dry standardized


NHPID Name:
Pancreatic Enzymes

Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.


NHPID Name:
Pancreatic Extract

New Additional Details added :
The only acceptable pharmaceutical dosage forms are delayed-release capsules, tablets, or granules (e.g. enteric-coated tablets, capsules containing enteric-coated granules/(mini)microspheres). The dosage form must be qualified with an additional term to describe the delayed release (e.g. enteric-coated capsules, gastro-resistant tablets, microencapsulated pancreatic enzymes) (WHO 2011).


NHPID Name:
Pancreatin

Modification:
Revised Category: Approved Biological Substance Name


NHPID Name:
Pancreatin

Modification:
New Schedule 1: Extract


NHPID Name:
Pancreatin

CAS Registry Number(s) removed:
8049-47-6


NHPID Name:
Pancreatin

New Method(s) of Preparation added:
Extract dry standardized


NHPID Name:
Pancreatin

New Additional Details added :
The only acceptable pharmaceutical dosage forms are delayed-release capsules, tablets, or granules (e.g. enteric-coated tablets, capsules containing enteric-coated granules/(mini)microspheres). The dosage form must be qualified with an additional term to describe the delayed release (e.g. enteric-coated capsules, gastro-resistant tablets, microencapsulated pancreatic enzymes) (WHO 2011).


NHPID Name:
Pancrelipase

Modification:
Revised Category: Approved Biological Substance Name


NHPID Name:
Pancrelipase

Modification:
New Schedule 1: Extract


NHPID Name:
Pancrelipase

CAS Registry Number(s) removed:
53608-75-6


NHPID Name:
Pancrelipase

New Additional Details added :
The only acceptable pharmaceutical dosage forms are delayed-release capsules, tablets, or granules (e.g. enteric-coated tablets, capsules containing enteric-coated granules/(mini)microspheres). The dosage form must be qualified with an additional term to describe the delayed release (e.g. enteric-coated capsules, gastro-resistant tablets, microencapsulated pancreatic enzymes) (WHO 2011).


NHPID Name:
Pancrelipase

New Method(s) of Preparation added:
Extract dry standardized


NHPID Name:
Fruit and Vegetable Blend (NMI)

New Additional Details added :
Fruit and vegetable blend is composed of any plant, fungus or algae whose leaves, roots, tubers, fruits, seeds, flowers, fruiting body or thallus are used for food. The quantity of the blend must be stated in the web PLA form. A cover letter listing all the components, including their Latin binomials, will need to be submitted with the product licence application. Each component of the blend has to be food safe.


NHPID Name:
Fruit and Vegetable Blend (NMI)

Additional Details removed:
Vegetable Blend is composed of any plant, edible fungus or edible algae whose leaves, roots, tubers, fruit, seeds, flowers, fruiting body or thallus are used for food, e.g. lettuce, potatoes, carrots, tomatoes, mushrooms and/or edible seaweeds.


NHPID Name:
Fruit and Vegetable Blend (NMI)

Toxicity Restriction removed:
Detail: The quantity of the blend must be stated in the ePLA. A cover letter listing all the components, including their Latin binomials, will need to be submitted with the Product License Application Form. Each ingredient with a non-medicinal role has to be food safe.


NHPID Name:
Fruit Blend (NMI)

New Additional Details added :
Fruit blend is composed of any plant whose fruits are used for food. The quantity of the blend must be stated in the web PLA form. A cover letter listing all the components, including their Latin binomials, will need to be submitted with the product licence application. Each component of the blend has to be food safe.


NHPID Name:
Fruit Blend (NMI)

Toxicity Restriction removed:
Detail: Fruit Blend is composed of any plant whose fruit and/or seeds are used for food. The quantity of the blend must be stated in the ePLA. A cover letter listing all the components, including their Latin binomials, will need to be submitted with the Product License Application Form. Each component of this ingredient has to be food safe.


NHPID Name:
Oleoresin Caraway

Modification:
Removed Schedule 1: Extract


NHPID Name:
Oleoresin Caraway

Source Material(s) removed:
Carum carvi ( Parts: Fruit oleoresin )


NHPID Name:
Oleoresin Caraway

New Source Material(s) added:
Carum carvi ( Parts: Seed oleoresin )


NHPID Name:
Olive Oil

New Source Material(s) added:
Olea europaea - Fruit


NHPID Name:
Olive Oil

New Sub-ingredient(s) added:
Linoleic acid; Oleic acid


NHPID Name:
Linoleic acid

New Source Material(s) added:
Olea europaea - Fruit


NHPID Name:
Oleic acid

New Source Material(s) added:
Olea europaea - Fruit


NHPID Name:
Blackcurrant Seed Oil

Medicinal Rationale changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.

RemIng

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