Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the
last update. This page was most recently revised on June 25, 2013.
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent versions of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest versions of the e-PLA, namely versions 1.4.4 and 2.2.0. Version 1.4.4, known as the Cfgm ePLA, is dedicated to applications of type Compendial from generated monographs (Cfgm), which are used when attesting to a generated single ingredient monograph. Version 2.2.0 is for all application types except for Compendial from generated monographs. The forms are available for downloading from http://www.hc-sc.gc.ca/dhp-mps/prodnatur/applications/online-enligne/guidance-reference-eng.php.
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
Pulvis Fellis Suis
Role:
Medicinal
NHPID Name:
Hydrolyzed Quinoa
Role:
Non-medicinal
NHPID Name:
Prunus serotina (Wild cherry) bark extract
Role:
Non-medicinal
NHPID Name:
Hydrolyzed Candida saitoana extract
Role:
Non-medicinal
NHPID Name:
Croton Glabellus Bark Oil
Role:
Non-medicinal
NHPID Name:
2-Phenanthrenol
Role:
Non-medicinal
NHPID Name:
Cyanotis vaga
Role:
Medicinal
NHPID Name:
Guar hydroxypropyltrimonium chloride
Role:
Non-medicinal
NHPID Name:
Hematite extract
Role:
Non-medicinal
NHPID Name:
Rhodochrosite extract
Role:
Non-medicinal
NHPID Name:
Copper nicotinate
Role:
Medicinal
NHPID Name:
Lespedeza capitata
Role:
Medicinal
NHPID Name:
Chai tea flavour
Role:
Non-medicinal
NHPID Name:
Galactoarabinan polyglucoronic acid cross polymer
Role:
Medicinal
NHPID Name:
Tabernaemontana divaricata
Role:
Medicinal
NHPID Name:
Scrophularia marilandica
Role:
Medicinal
NHPID Name:
Aconitum chasmanthum
Role:
Medicinal
NHPID Name:
Juniperus Virginiana Essential Oil
Role:
Non-medicinal
NHPID Name:
B-vitamins-enriched Quinoa sprout
Role:
Medicinal, Non-medicinal & Non-NHP
NHPID Name:
Juglans Regia (Walnut) Seed Extract
Role:
Non-medicinal
NHPID Name:
Wikstroemia indica
Role:
Medicinal
NHPID Name:
Peach mango flavour
Role:
Non-medicinal
NHPID Name:
Argania spinosa sprout cell extract
Role:
Non-medicinal
NHPID Name:
Olea europaea (Olive) seed powder
Role:
Medicinal
NHPID Name:
Tiliacora Triandra
Role:
Non-medicinal
NHPID Name:
Cordia latifolia
Role:
Medicinal
NHPID Name:
Diospyros virginiana
Role:
Medicinal
NHPID Name:
Dabrafenib
Role:
Non-NHP
NHPID Name:
Vortioxetine
Role:
Non-NHP
NHPID Name:
Omphalia lapidescens
Role:
Medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
No Changes.
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Semen Nelumbinus
New NHPID Name:
Semen Nelumbinis
Old NHPID Name:
Folium Nelumbinus
New NHPID Name:
Folium Nelumbinis
Old NHPID Name:
Nodus Nelumbinus Rhizomatis
New NHPID Name:
Nodus Nelumbinis Rhizomatis
Old NHPID Name:
Plumula Nelumbinus
New NHPID Name:
Plumula Nelumbinis
Old NHPID Name:
Receptaculum Nelumbinus
New NHPID Name:
Receptaculum Nelumbinis
Old NHPID Name:
Stamen Nelumbinus
New NHPID Name:
Stamen Nelumbinis
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
Vegetable oil
New Common Name(s):
Olus oil
NHPID Name:
Sea Silt Extract
New Common Name(s):
Maris limus extract
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
NHPID Name:
DL-Methionine
Old Role:
Non-medicinal
New Role:
Medicinal & Non-medicinal
NHPID Name:
Nicotinoyl-GABA
Old Role:
Medicinal
New Role:
Non-medicinal
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Undecenoic acid
New Route(s) of Adminstration added:
Topical
NHPID Name:
Acorus calamus
New Medicinal Restriction(s) added :
Products containing Acorus species should be tested at the finished product or raw material stage to show absence of beta-asarone. Alternatively, genetic typing at the raw material stage to show a diploid karyotype is also acceptable.
NHPID Name:
Acorus calamus var. angustatus
New Medicinal Restriction(s) added :
Products containing Acorus species should be tested at the finished product or raw material stage to show absence of beta-asarone. Alternatively, genetic typing at the raw material stage to show a diploid karyotype is also acceptable.
NHPID Name:
Borago officinalis
New Medicinal Restriction(s) added :
Leaves, stems and extracts of Borago officinalis must be tested to ensure absence of unsaturated pyrrolizidine alkaloids.
NHPID Name:
Eupatorium perfoliatum; Eupatorium purpureum
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Eupatorium purpureum.
NHPID Name:
Hydrangea arborescens
New Medicinal Restriction(s) added :
Testing must be performed to ensure absence of cyanogenic glycosides in Hydrangea arborescens.
NHPID Name:
Glycerol
New Medicinal Restriction(s) added :
For oral use, other than when present as part of the capsule shell, Glycerol shall contain no more than 0.1% diethylene glycol and related compounds
NHPID Name:
Equisetum arvense
New Medicinal Restriction(s) added :
Testing must be performed to ensure absence of thiaminase-like activity in Equisetum arvense.
NHPID Name:
Arthrospira maxima; Arthrospira platensis
New Medicinal Restriction(s) added :
As Spirulina species contain predominantly pseudo-vitamin B12, potencies of vitamin B12 are only acceptable if the supporting assays are based on the amount of bioactive, rather than bioavailable, vitamin B12.
NHPID Name:
Symphytum officinale
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids (e.g. Echimidine) in Symphytum officinale.
NHPID Name:
Tussilago farfara
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Tussilago farfara.
NHPID Name:
Petasites hybridus
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Petasites hybridus.
NHPID Name:
Piper methysticum
New Medicinal Restriction(s) added :
The amount of kavalactones in Piper methysticum should be provided for the Safety and Efficacy assessment of Product Licence Applications.
NHPID Name:
Shark cartilage
New Medicinal Restriction(s) added :
Testing must be performed to ensure absence of beta-N-Methylamino-L-alanine (BMAA)
NHPID Name:
Viscum album
New Medicinal Restriction(s) added :
Testing must be performed on Viscum album to ensure a maximum level of viscotoxin in the finished product of 17 µg/mL (or µg/g).
NHPID Name:
Senecio scandens
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Senecio scandens.
NHPID Name:
Hyoscyamus niger
New Route(s) of Adminstration added:
Oral
Detail: Hyoscyamus niger leaf, root and seed contain the toxic constituents Hyoscine (Scopolamine) and Hyoscyamine.
NHPID Name:
Inositol
New Non-medicinal Restriction(s) added:
Diluent
NHPID Name:
Clary Sage Essential Oil
New Non-medicinal Restriction(s) added:
Fragrance Ingredient
NHPID Name:
alpha-Terpinyl acetate
New Non-medicinal Restriction(s) added:
Fragrance Ingredient
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
Butyric acid
New Source Ingredient(s) added:
Calcium dibutyrate; Magnesium dibutyrate
NHPID Name:
Polyphenol Type-A Polymers
New Source Material(s) added:
Cinnamomum burmannii (Parts: Whole plant)
NHPID Name:
Vegetable oil
New NMI Purpose(s):
Skin-Conditioning Agent - Emollient
NHPID Name:
Sea Silt Extract
New NMI Purpose(s):
Skin Protectant
NHPID Name:
Sea Silt Extract
New Additional Details added :
Topical use only.
NHPID Name:
Undecenoic acid
New NMI Purpose(s):
Cosmetic Biocide; Emulsifying Agent; Fragrance Ingredient; Surfactant - Cleansing Agent
NHPID Name:
Oregano Oil
New Source Material(s) added:
Origanum minutiflorum
NHPID Name:
Folate
New Source Material(s) added:
Arthrospira platensis
NHPID Name:
Acetogenins
New Source Material(s) added:
Asimina triloba ( Parts: Twig )
NHPID Name:
Licochalcone A
New Source Material(s) added:
Glycyrrhiza inflata; Glycyrrhiza glabra
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
No Changes.
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
No Changes.
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
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