Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the
last update. This page was most recently revised on August 28, 2012.
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent versions of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest versions of the e-PLA, namely versions 1.4.4 and 2.0.1. Version 1.4.4, known as the Cfgm ePLA, is dedicated to applications of type Compendial from generated monographs (Cfgm), which are used when attesting to a generated single ingredient monograph. Version 2.0.1 is for all application types except for Compendial from generated monographs. The forms are available for downloading from http://www.hc-sc.gc.ca/dhp-mps/prodnatur/applications/online-enligne/guidance-reference-eng.php.
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
Calcium nitrate
Role:
NA
NHPID Name:
Calcite
Role:
NA
NHPID Name:
Picea Abies Leaf Oil
Role:
Medicinal and Non-medicinal
NHPID Name:
Rubus Chamaemorus Seed Oil
Role:
Non-medicinal
NHPID Name:
Callitris Introtropica Wood Oil
Role:
Non-medicinal
NHPID Name:
Fish Protein Hydrolysate
Role:
Medicinal
NHPID Name:
Periostracum Serpentis
Role:
Medicinal
NHPID Name:
Rhizoma Bolbostematis
Role:
Medicinal
NHPID Name:
Vinpocetine
Role:
Medicinal
NHPID Name:
Caulis Dendrobii
Role:
Medicinal
NHPID Name:
Lapis Micae Aureus
Role:
Medicinal
NHPID Name:
Ext. D&C Violet No. 2
Role:
Non-medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
NHPID Name:
Radix Ligustici Chuanxiong
Role:
Medicinal
NHPID Name:
Green 5
Role:
Non-medicinal
NHPID Name:
Red 6
Role:
Non-medicinal
NHPID Name:
Red 33
Role:
Non-medicinal
NHPID Name:
Violet 2
Role:
Non-medicinal
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Medium chain triglycerides
New NHPID Name:
Medium-chain triglycerides
Old NHPID Name:
Bergamot Oil Coldpressed
New NHPID Name:
Bergamot Essential Oil
Old NHPID Name:
FD&C Blue No. 1 aluminum lake
New NHPID Name:
FD&C Blue No. 1 Aluminum Lake
Old NHPID Name:
Red 30 Lake
New NHPID Name:
D&C Red No. 30 Aluminum Lake
Old NHPID Name:
Red 7 Lake
New NHPID Name:
D&C Red No. 7 Aluminum Lake
Old NHPID Name:
Red 33 Lake
New NHPID Name:
D&C Red No. 33 Aluminum Lake
Old NHPID Name:
CI 18965
New NHPID Name:
C.I. 18965
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
Medium-chain triglycerides
New Proper Name(s):
Medium-chain triglycerides
NHPID Name:
Medium-chain triglycerides
Removed Proper Name(s):
Medium chain triglycerides
NHPID Name:
Dendrobium nobile
Removed Common Name(s):
Dendrobium; Shihu
NHPID Name:
Bergamot Essential Oil
Removed Proper Name(s):
Citrus aurantium
NHPID Name:
Bergamot Essential Oil
New Proper Name(s):
Citrus bergamia
NHPID Name:
Bergamot Essential Oil
Removed Common Name(s):
Neroli bigarde; Bergamot Oil Coldpressed
NHPID Name:
Bergamot Essential Oil
New Common Name(s):
Bergamot Essential Oil; Bergamot Essential Oil Coldpressed
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
Removed Proper Name(s):
Citrus aurantium
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
New Proper Name(s):
Citrus bergamia
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
Removed Common Name(s):
Bergamot Oil; Citrus Aurantium Bergamia (Bergamot) Fruit Oil
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
New Common Name(s):
Citrus Aurantium Bergamia (Bergamot) Fruit Essential Oil
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Leaf Oil
Removed Proper Name(s):
Citrus aurantium
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Leaf Oil
New Proper Name(s):
Citrus bergamia
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Leaf Oil
Removed Common Name(s):
Citrus Aurantium Bergamia (Bergamot) Leaf Oil
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Leaf Oil
New Common Name(s):
Citrus Aurantium Bergamia (Bergamot) Leaf Essential Oil
NHPID Name:
Rhizoma Chuanxiong
Removed Proper Name(s):
Ligusticum sinense
NHPID Name:
Rhizoma Chuanxiong
New Proper Name(s):
Ligusticum sinense cv. chuanxiong
NHPID Name:
Alizarin cyanine green F
New Common Name(s):
C.I. 61570, D&C Green No. 5
NHPID Name:
Lithol Rubin B
New Common Name(s):
D&C Red No. 6, Lithol Rubin B
NHPID Name:
Lithol Rubin B Ca
New Common Name(s):
D&C Red No. 7, Lithol Rubin B Ca
NHPID Name:
D&C Red No. 7 Aluminum Lake
Removed Proper Name(s):
Red 7 Lake
NHPID Name:
D&C Red No. 7 Aluminum Lake
New Proper Name(s):
D&C Red No. 7 Aluminum Lake
NHPID Name:
C.I. Acid Red 33, disodium salt
New Common Name(s):
Acid Fuchsin D, C.I. 17200, D&C Red No. 33
NHPID Name:
D&C Red No. 33 Aluminum Lake
Removed Proper Name(s):
Red 33 Lake
NHPID Name:
D&C Red No. 33 Aluminum Lake
New Proper Name(s):
D&C Red No. 33 Aluminum Lake
NHPID Name:
D&C Violet No. 2
New Proper Name(s):
D&C Violet No. 2
NHPID Name:
D&C Violet No. 2
Removed Common Name(s):
Acid violet 43, C.I. No. 60730
NHPID Name:
D&C Violet No. 2
New Common Name(s):
C.I. 60725
NHPID Name:
Pigment Yellow 13
Removed Common Name(s):
CI 21100
NHPID Name:
Pigment Yellow 13
New Common Name(s):
C.I. 21100
NHPID Name:
C.I. 18965
Removed Proper Name(s):
CI 18965
NHPID Name:
C.I. 18965
New Proper Name(s):
Acid yellow 17
NHPID Name:
C.I. 18965
Removed Common Name(s):
Food Yellow 5
NHPID Name:
C.I. 18965
New Common Name(s):
C.I. 18965, Acid yellow 17
NHPID Name:
Copper phthalocyanine
Removed Common Name(s):
CI 74160
NHPID Name:
Copper phthalocyanine
New Common Name(s):
C.I. 74160
NHPID Name:
D&C Red No. 36
Removed Common Name(s):
C.I. No. 12085
NHPID Name:
D&C Red No. 36
New Common Name(s):
C.I. 12085
NHPID Name:
Fast Green FCF
Removed Common Name(s):
C.I. No. 42053
NHPID Name:
Fast Green FCF
New Common Name(s):
C.I. 42053
NHPID Name:
Iron Oxides
Removed Common Name(s):
CI 77491, CI 77492, CI 77499
NHPID Name:
Iron Oxides
New Common Name(s):
C.I. 77491, C.I. 77492, C.I. 77499
NHPID Name:
Zinc ascorbate
New Proper Name(s):
L-Ascorbic acid, zinc salt
NHPID Name:
Magnesium Phosphate, tribasic
New Common Name(s):
Magnesium phosphate anhydrous
NHPID Name:
Magnesium phosphate tribasic pentahydrate
New Common Name(s):
Magnesium phosphate pentahydrate
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
No Changes.
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Fragaria Chiloensis (Strawberry) Fruit Juice
Route(s) of Adminstration removed:
Topical
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
New Route(s) of Adminstration added:
Topical
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Leaf Oil
New Route(s) of Adminstration added:
Topical
NHPID Name:
Lithol Rubin B
New Non-medicinal Restriction(s) added:
Colouring agent only. In oral products, the combined total of D&C Red No. 6 and D&C Red No. 7 must not exceed 5 milligrams per daily dose of the product.
NHPID Name:
Lithol Rubin B Ca
New Non-medicinal Restriction(s) added:
Colouring agent only. In oral products, the combined total of D&C Red No. 6 and D&C Red No. 7 must not exceed 5 milligrams per daily dose of the product.
NHPID Name:
C.I. Acid Red 33, disodium salt
New Non-medicinal Restriction(s) added:
Colouring agent only. In oral products, up to 0.75 mg per day.
NHPID Name:
D&C Violet No. 2
New Route(s) of Adminstration added:
Topical
NHPID Name:
D&C Violet No. 2
New Non-medicinal Restriction(s) added:
Topical use only
NHPID Name:
Pigment Yellow 13
New Route(s) of Adminstration added:
Topical
NHPID Name:
Pigment Yellow 13
New Non-medicinal Restriction(s) added:
Topical use only
NHPID Name:
D&C Red No. 36
New Non-medicinal Restriction(s) added:
In oral products, up to 1.0 mg per day, unless additional evidence for safety is submitted.
NHPID Name:
Iron Oxides
New Non-medicinal Restriction(s) added:
In oral products, up to 5 mg per day calculated as elemental iron
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
Fragaria Chiloensis (Strawberry) Fruit Juice
New NMI Purpose(s):
Skin-Conditioning Agent
NHPID Name:
Medium-chain triglycerides
New NMI Purpose(s):
Filler; Lubricant
NHPID Name:
Carthamus tinctorius
Additional Details changed:
A transgenetic form of Carthamus tinctorius cannot be a medicinal ingredient as a NHP. Drugs obtained by recombinant DNA procedures are listed in the Schedule D of the Food and Drugs Act. Schedule D substances are excluded from NHP regulations; therefore, drugs obtained by recombinant DNA procedures, including transgenic forms of any organisms, are not NHPs.
NHPID Name:
D&C Red No. 27 Aluminum Lake
Toxicity Restriction changed:
Acceptable daily intake is up to 1.25 mg/kg body weight for Tetrachlorotetrabromofluorescein and its derivatives, expressed as Tetrachlorotetrabromofluorescein (Environment Canada and Health Canada, http://www.ec.gc.ca/ese-ees/default.asp?lang=En&n=23C03477-1). Tolerable weekly intake for aluminium and its salts, is up to 1 mg/kg body weight, expressed as aluminium. (Scientific Opinion on the re-evaluation of Erythrosine (E 127) as a food additive, EFSA Journal 9(1):1854, 2011, http://www.efsa.europa.eu/en/efsajournal).
NHPID Name:
Magnesium
New Source Material(s) added:
Magnesium aspartate dihydrate; Magnesium aspartate tetrahydrate; L-Aspartic acid, magnesium salt (2:1); Magnesium aspartate hydrochloride trihydrate
NHPID Name:
Phytosterols
New Source Ingredient(s) added:
Tall oil
NHPID Name:
Bergamot Essential Oil
Method(s) of Preparation removed:
Oil, Essential (enfleurage) , Oil, Essential (enfleurage) Standardised , Oil, Essential (expression) , Oil, Essential (expression) Standardised , Oil, Essential (other methods of preparation) , Oil, Essential (other methods of preparation) Standardised , Oil, Essential (water steam distillation) , Oil, Essential (water steam distillation) Standardised
NHPID Name:
Bergamot Essential Oil
New Method(s) of Preparation added:
Oil, Essential (expression) , Oil, Essential (expression) Standardised
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
New Additional Details added :
Topical use only.
NHPID Name:
Citrus Aurantium Bergamia (Bergamot) Leaf Oil
New Additional Details added :
Topical use only.
NHPID Name:
Pigment Yellow 13
New CAS Registry Number(s) added:
5102-83-0
NHPID Name:
C.I. 18965
New CAS Registry Number(s) added:
6359-98-4
NHPID Name:
Fast Green FCF
Toxicity Restriction removed:
External or internal use in pharmaceutical dosage forms (Part C.01.040.2)
NHPID Name:
Fast Green FCF
New Toxicity restriction added:
Acceptable daily intake up to 25 mg/kg body weight daily
NHPID Name:
Iron Oxides
New Toxicity restriction added:
Acceptable daily intake up to 0.5 mg/kg body weight daily
NHPID Name:
Protodioscin
CAS Registry Number(s) removed:
55056-80-9
NHPID Name:
Protodioscin
Name Reference removed:
ICID
NHPID Name:
Protodioscin
New Name Reference added:
J_PHARM_SCI_90(1752)
NHPID Name:
Protodioscin
New Source Material(s) added:
Tribulus terrestris (Part: Root)
NHPID Name:
Eicosapentaenoic acid
New Source Material(s) added:
Schizochytrium spp. (Parts: Whole)
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
No Changes.
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
No Changes.
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
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