Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on July 17, 2012.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent versions of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest versions of the e-PLA, namely versions 1.4.4 and 2.0.1. Version 1.4.4, known as the Cfgm ePLA, is dedicated to applications of type Compendial from generated monographs (Cfgm), which are used when attesting to a generated single ingredient monograph. Version 2.0.1 is for all application types except for Compendial from generated monographs. The forms are available for downloading from http://www.hc-sc.gc.ca/dhp-mps/prodnatur/applications/online-enligne/guidance-reference-eng.php.


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Ceramide 1

Role:
Non-medicinal


NHPID Name:
Stachys Officinalis Flower/Leaf/Stem Extract

Role:
Non-medicinal


NHPID Name:
Soy Isoflavones

Role:
Non-medicinal


NHPID Name:
Acetyl glucosamine

Role:
Non-medicinal


NHPID Name:
Ethylbisiminomethylguaiacol Manganese Chloride

Role:
Non-medicinal


NHPID Name:
Ferula gummosa gum resin

Role:
Non-medicinal


NHPID Name:
Yolk protein

Role:
Medicinal


NHPID Name:
Mimosa tenuiflora leaf extract

Role:
Non-medicinal


NHPID Name:
Safflower Oil/Palm Oil Aminopropanediol Esters

Role:
Non-medicinal


NHPID Name:
Fragaria virginiana fruit

Role:
Non-medicinal


NHPID Name:
Zinc citrate trihydrate

Role:
Medicinal


NHPID Name:
Saponaria officinalis

Role:
Medicinal


NHPID Name:
Cordyceps

Role:
Medicinal


NHPID Name:
Mandarin orange fruit

Role:
Non-medicinal


NHPID Name:
Coprinus comatus

Role:
Medicinal


NHPID Name:
Coconut Alkanes

Role:
Non-medicinal


NHPID Name:
Placental protein

Role:
Non-medicinal


NHPID Name:
PPG-9 Diglyceryl Ether

Role:
Non-medicinal


NHPID Name:
Sodium Carbonate Peroxide

Role:
Non-medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

NHPID Name:
Mastic, Storax, Molasses, Gum Benzoin

Role:
Medicinal


NHPID Name:
Lime Oil Distilled, Lime Oil Coldpressed

Role:
Non-medicinal


NHPID Name:
Mace Oil, East Indian

Role:
Medicinal & Non-medicinal


NHPID Name:
Mace Oil, West Indian

Role:
Medicinal & Non-medicinal


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:
Linaloe Wood Oil

New NHPID Name:
Linaloe Wood Essential Oil


Old NHPID Name:
Lovage Oil

New NHPID Name:
Lovage Essential Oil


Old NHPID Name:
Mace Oil

New NHPID Name:
Mace Essential Oil


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Ascophyllum nodosum

New Common Name(s):
Norwegian Kelp


NHPID Name:
Colforsin

Removed Common Name(s):
Forskolin


NHPID Name:
Colforsin

New Common Name(s):
Colforsin


NHPID Name:
Hypromellose

New Common Name(s):
Hydroxypropyl Methylcellulose


NHPID Name:
Tanacetum annuum (Tansy) Essential Oil

Removed Proper Name(s):
Votiga annua


NHPID Name:
Lonicera Japonica (Honeysuckle) Flower Extract

New Common Name(s):
Lonicera Japonica (Honeysuckle) Flower Extract


NHPID Name:
Citrus Grandis Fruit Extract

Removed Common Name(s):
Citrus Grandis (Grapefruit) Fruit Extract


NHPID Name:
Trametes versicolor

New Common Name(s):
Kawaratake, Turkey Tail


NHPID Name:
Capsicum annuum

New Common Name(s):
Cayenne pepper, Chili pepper


NHPID Name:
Tanacetum annuum (Tansy) Essential Oil

New Proper Name(s):
Vogtia annua


NHPID Name:
Citrus Aurantifolia (Lime) Oil

Removed Proper Name(s):
Citrus aurantium


NHPID Name:
Citrus Aurantifolia (Lime) Oil

New Proper Name(s):
Citrus aurantiifolia


NHPID Name:
Citrus Aurantifolia (Lime) Oil

Removed Common Name(s):
Citrus Aurantifolia (Lime) Oil, Lime Oil


NHPID Name:
Citrus Aurantifolia (Lime) Oil

New Common Name(s):
Citrus Aurantifolia Essential Oil, Lime Essential Oil


NHPID Name:
Linaloe Wood Essential Oil

New Common Name(s):
Linaloe Wood Essential Oil


NHPID Name:
Linaloe Wood Essential Oil

Removed Common Name(s):
Linaloe Wood Oil


NHPID Name:
Lovage Essential Oil

New Common Name(s):
Lovage Essential Oil


NHPID Name:
Lovage Essential Oil

Removed Common Name(s):
Lovage Oil


NHPID Name:
Mace Essential Oil

New Common Name(s):
Mace Essential Oil


NHPID Name:
Mace Essential Oil

Removed Common Name(s):
Mace Oil


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
Cannabis sativa Seed Oil

Old Role:
Non-medicinal

New Role:
Medicinal et Non-medicinal


NHPID Name:
Mace Essential Oil

Old Role:
Medicinal

New Role:
Medicinal and Non-medicinal


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Mica

New Route(s) of Adminstration added:
Oral


NHPID Name:
PEG-3 Oleate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Several ingredients

New Route(s) of Adminstration added:
Oral


NHPID Name:
Citrus Aurantifolia (Lime) Oil

New Route(s) of Adminstration added:
Oral


NHPID Name:
Mace Essential Oil

New Route(s) of Adminstration added:
Oral


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Mica

New Additional Details added :
Permitted as a colouring agent for dental use. (For Dental)


NHPID Name:
Mica

New Toxicity restriction added:
3% w/w (For Oral)


NHPID Name:
Mica

New Additional Details added :
Mica-based pearlescent pigments may be safely used to color ingested drugs in amounts up to 3 percent, by weight, of the final drug product. The maximum amount of iron oxide to be used in producing said pigments is not to exceed 55 percent, by weight, in the finished pigment. Reference: FDA 2011. 21CFR73 Listing of color additives exempt from certification. Subpart B - Drugs. Sec. 73.1350 Mica-based pearlescent pigments. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?CFRPart=73&showFR=1&subpartNode=21:1.0.1.1.26.2


NHPID Name:
Cannabis sativa

New Sub-ingredient(s) added:
alpha-Linolenic acid, gamma-Linolenic acid, Linoleic acid


NHPID Name:
Plectranthus barbatus

New Sub-ingredient(s) added:
Forskolin


NHPID Name:
Silver diamine fluoride

New Source Ingredient(s) added:
Fluoride, Silver


NHPID Name:
Hypromellose

New NMI Purpose(s):
Emulsion Stabilizer; Viscosity Increasing Agent - Aqueous


NHPID Name:
Hypromellose

New Toxicity restriction added:
In topical products up to 36%, unless additional evidence for safety is submitted.


NHPID Name:
PEG-3 Oleate

New NMI Purpose(s):
Dissolution Enhancing Agent, Emulsifying Agent, Solubilizing Agent


NHPID Name:
Eurycoma longifolia

New Sub-ingredient(s) added:
Eurypeptides, Glycosaponins


NHPID Name:
Magnesium sulfate dihydrate, Magnesium sulfate heptahydrate, Magnesium sulfate trihydrate

New Toxicity restriction added:
Up to 0.7 mg/kg body weight daily expressed as sulfur dioxide. Must be declared as a medicinal ingredient in saline laxative products at or above doses of magnesium sulfate of 10 g/d. Must be declared as a medicinal ingredient in mineral products at or above 50 mg/d as Mg from all sources.


NHPID Name:
Saponaria officinalis

New Source Material(s) added:
Quillaic acid


NHPID Name:
Liquid Sorbitol (Non-crystallising)

New NMI Purpose(s):
Humectant, Sweetening Agent


NHPID Name:
3-Phenyl-1-propanol

New NMI Purpose(s):
Flavour Enhancer


NHPID Name:
Blakeslea trispora

New Source Material(s) added:
Mixed carotenoids


NHPID Name:
Halite

New Source Ingredient(s) added:
Sodium chloride


NHPID Name:
Brassica oleracea var. italica

New Source Ingredient(s) added:
Folate


NHPID Name:
Ethyl lactate

Additional Details removed:
Ethyl lactate is a source of lactic acid, which is an alpha-hydroxy acid. The presence of alpha-hydroxy acids (AHAs), including lactic acid, on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. Ethyl lactate cannot be used in topical natural health products except in accordance with the restrictions for alpha-hydroxy acids set out on the Hotlist unless additional evidence of their safety is submitted. Information regarding the pH of the product and quantity of ethyl lactate it contains must also be provided. Reference: CIH. http://www.hc-sc.gc.ca/cps-spc/cosmet-person/indust/hot-list-critique/hotlist-liste-eng.php#A


NHPID Name:
Aloe Barbadensis Leaf Extract

New Additional Details added :
Flavour enhancer is for dental use only (For Topical)


NHPID Name:
Cannabis sativa Seed Oil

New Toxicity restriction added:
Upper Limit: 10.0 Parts per million


NHPID Name:
Cannabis sativa Seed Oil

New Additional Details added :
Hemp products cannot contain more than 10 ppm of delta-9-tetrahydro-cannabinol (THC), and their production must be in compliance with the Industrial Hemp Regulations.


NHPID Name:
Cannabis sativa Seed Oil

New Source Material(s) added:
Oleic acid


NHPID Name:
Cannabis sativa Seed Oil

New NMI Purpose(s):
Oleaginous Vehicle; Dispersing agent


NHPID Name:
Citrus Aurantifolia (Lime) Oil

New NMI Purpose(s):
Flavour Enhancer


NHPID Name:
Citrus Aurantifolia (Lime) Oil

New Additional Details added :
Flavouring agent only (For Oral)


NHPID Name:
Citrus Aurantifolia (Lime) Oil

New Toxicity restriction added:
When used in cosmetic products, the total concentration of furocoumarin-like substances in the finished product must not exceed 1 ppm.


NHPID Name:
Linaloe Wood Essential Oil

Method(s) of Preparation removed:
Oil, Essential (enfleurage); Oil, Essential (enfleurage) Standardised; Oil, Essential (expression); Oil, Essential (expression) Standardised; Oil, Essential (other methods of preparation); Oil, Essential (other methods of preparation) Standardised


NHPID Name:
Lovage Essential Oil

Method(s) of Preparation removed:
Oil, Essential (enfleurage); Oil, Essential (enfleurage) Standardised; Oil, Essential (expression); Oil, Essential (expression) Standardised; Oil, Essential (other methods of preparation); Oil, Essential (other methods of preparation) Standardised


NHPID Name:
Mace Essential Oil

Method(s) of Preparation removed:
Oil, Essential (enfleurage); Oil, Essential (enfleurage) Standardised; Oil, Essential (expression); Oil, Essential (expression) Standardised; Oil, Essential (other methods of preparation); Oil, Essential (other methods of preparation) Standardised


NHPID Name:
Mace Essential Oil

New NMI Purpose(s):
Flavour enhancer


NHPID Name:
Mace Essential Oil

New Additional Details added :
Flavouring agent only


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

Modification:
Addition of the following new monographs: Active hexose correlated compound - Granule, Active hexose correlated compound - Powder, Poria - Wolfiporia extensa, Cassia cinnamon - Cinnamomum aromaticum, Quercetin, Rutin, Amla - Phyllanthus emblica, and Dong quai - Angelica sinensis.


Modification:
Revisions to the fish oil monograph following consultation


Modification:
Revisions following consultation and conversion of the following from AbLS to monograph: Krill oil, Alpha-Amylase, Fruit Bromelain, Stem Bromelain


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.


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