Malabar tamarind - Garcinia gummi-gutta
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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.
Notes- Text in parentheses is additional optional information which can be included on the PLA and product label at the applicant's discretion.
- The solidus (/) indicates that the terms and/or statements are synonymous. Either term or statement may be selected by the applicant.
Date
July 31, 2018
Proper name(s), Common name(s), Source material(s)
Proper name(s) | Common name(s) | Source material(s) | |
---|---|---|---|
Proper name(s) | Part(s) | ||
Garcinia gummi-gutta | Malabar tamarind | Garcinia gummi-gutta | Fruit peel |
References: Proper name: USDA 2018, McGuffin et al. 2000; Common name: USDA 2018; Source material: Hayamizu et al. 2008.
Route of administration
Oral
Dosage form(s)
This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.
Acceptable dosage forms for the age category listed in this monograph and specified route of administration are indicated in the Compendium of Monographs Guidance Document.
Use(s) or Purpose(s)
Could help to temporarily increase satiety/feeling of fullness (Gatta et al. 2009).
Dose(s)
Subpopulation(s)
Adults 18 years and older
Quantity(ies)
Methods of preparation: Standardized extracts
2-3 grams of extract standardized to 50-60% hydroxycitric acid, per day; 1.5-2 grams of extract per single dose (Kim et al. 2011; Gatta et al. 2009; Ishii et al. 2003; Heymsfield et al. 1998).
Directions for use
Take before meals.
Duration of use
No statement required.Risk information
Caution(s) and warning(s)
Consult a health care practitioner/health care provider/health care professional/doctor/physician prior to use if you are pregnant or breastfeeding.Contraindication(s)
No statement required.Known adverse reaction(s)
No statement required.Non-medicinal ingredients
Must be chosen from the current NNHPD Natural Health Products Ingredients Database (NHPID) and must meet the limitations outlined in the database.Storage conditions
No statement required.Specifications
- The finished product specifications must be established in accordance with the requirements described in the Natural and Non-prescription Health Products Directorate (NNHPD) Quality of Natural Health Products Guide.
- The medicinal ingredient must comply with the requirements outlined in the NHPID.
References cited
- Gatta B, Zuberbuehler C, Arnold M, Aubert R, Langhans W, Chapelot D. Acute effects of pharmacological modifications of fatty acid metabolism on human satiety. British Journal of Nutrition 2009; 101: 1867-1877
- Hayamizu K, Tomi H, Kaneko I, Shen M, Soni MG, Yoshino G. Effects of Garcinica cambogia extract on serum sex hormones in overweight subjects. Fitoterapia 2008; 79: 255-261
- Heymsfield SB, Allison DB, Vasselli JR, Pietrobelli A, Greenfield D, Nunez C. Garcinia cambogia (Hydroxycitric acid) as a potential antiobesity agent, a randomized controlled trial. Journal of the American Medical Association 1998; 280(18): 1596-1600
- Ishii Y, Kaneko I, Shen M, Hayamizu K, Shigematsu N, Tomi H, Yoshino G, Shimaski H. Safety of Garcinia cambogia extract in healthy volunteers: High-dose administration study II. Journal of Oleo Science 2003; 52(12): 663-671
- Kim JE, Jeon SM, Park KH, Lee WS, Jeong TS, McGregor RA, Choi MS. Does Glycine max leaves or Garcinia Cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: a randomized control trial. Nutrition Journal 2011; 10: 94
- McGuffin M, Kartesz JT, Leung AY, Tucker AO, editors. Herbs of Commerce. 2nd edition. Silver Spring (MD): American Herbal Products Association; 2000.
- USDA 2018: United States Department of Agriculture, Agricultural Research Service, National Genetic Resources Program. Germplasm Resources Information Network (GRIN). Garcinia gummi-gutta L [Internet]. National Germplasm Resources Laboratory, Beltsville (MD). [Accessed 2018 June 1]. Available from: http://www.ars-grin.gov/cgi-bin/npgs/html/tax_search.pl
References reviewed
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