Monograph: Gentian

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Date: 2019-07-01

NHPID name

Gentiana lutea ( Germplasm Resources Information Network Taxonomy )

Proper name(s)

Gentiana lutea ( USDA 2008 )

Common name(s)

Source material

Root ( Blumenthal et al. 2000 )

Route Of administration


Dosage form(s)

Those suited to the allowable route(s) of administration. This monograph is not intended to include food-like dosage forms such as bars, chewing gums or beverages.

Use(s) or purpose(s)

Statement(s) to the effect of:




1 Day per day

Directions for use: Take 15 - 60 minutes before meals.

See Appendix 1 for examples of appropriate dosage preparations and frequencies of use, according to cited references. The purpose of Appendix 1 is to provide guidance to industry.

Duration of use

No statement is required

Risk information

Statement(s) to the effect of:

Caution(s) and Warning(s): Contraindication(s): Do not use this product if you are pregnant or have acute stomach irritation, inflammation and stomach or duodenal ulcers.  (ESCOP 2003, Brinker 2001, Bradley 1992) Known Adverse Reaction(s): Some people may experience headaches.  (ESCOP 2003, Hoffmann 2003, Blumenthal et al. 2000)

Non-medicinal ingredients

Must be chosen from the current Natural health products ingredients database and must meet the limitations outlined in the database.


References cited

References reviewed

Appendix 1: Examples of appropriate dosage preparations, frequencies of use and directions for use

Dried root:

Infusion or decoction:

Directions for use (infusion):

Pour 150 ml of boiling water (Blumenthal et al. 2000) over dried root, steep for 5 minutes and strain (Wichtl 2004).



Solid extract:

0.2-0.4 g dried equivalent, 2-3 times per day
(3.5-4.5:1) (Blumenthal et al. 2000)