Monograph: MSM

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Date: 2022-12-30

NHPID name

Dimethyl sulfone ( O'Neil et al. 2012 )

Proper name(s)

Common name(s)

Source material

Dimethyl sulfone (O'Neil et al. 2006)

Route Of administration


Dosage form(s)

Those suited to the allowable route(s) of administration. This monograph is not intended to include food-like dosage forms such as bars, chewing gums or beverages.

Use(s) or purpose(s)

Statement(s) to the effect of:

Helps to relieve (joint) pain associated with osteoarthritis (of the knee).  (Kim et al. 2006, Usha and Naidu 2004)




1 Day per day

Directions for use:
  • Avoid taking at bedtime.
  • Take with food.

Duration of use

Use for at least 1 month to see beneficial effects.  (Kim et al. 2006, Usha and Naidu 2004)

Risk information

Statement(s) to the effect of:

Caution(s) and Warning(s): Contraindication(s): No statement is required Known Adverse Reaction(s): Some people may experience mild gastrointestinal bloating, constipation or indigestion.  (Kim et al. 2006)

Non-medicinal ingredients

Must be chosen from the current Natural health products ingredients database and must meet the limitations outlined in the database.


References cited

References reviewed