Monograph: Horse Chestnut

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Date: 2018-12-18

NHPID name

Aesculus hippocastanum ( Germplasm Resources Information Network Taxonomy )

Proper name(s)

Aesculus hippocastanum ( USDA 2008 )

Common name(s)

Source material

Seed ( Bradley 2006 , Blumenthal et al. 2000 )

Route Of administration

Oral ( Bradley 2006 , ESCOP 2003 )

Dosage form(s)

Those suited to the allowable route(s) of administration. This monograph is not intended to include food-like dosage forms such as bars, chewing gums or beverages.

Use(s) or purpose(s)

Statement(s) to the effect of:




1 Day per day

See Appendix 1 for examples of appropriate dosage preparations and frequencies of use, according to cited references. The purpose of Appendix 1 is to provide guidance to industry.

Duration of use

No statement is required

Risk information

Statement(s) to the effect of:

Caution(s) and Warning(s): Contraindication(s): No statement is required Known Adverse Reaction(s): Some people may experience headache, dizziness, gastric irritation, or itchiness.  (Bradley 2006, Mills and Bone 2005, ESCOP 2003)

Non-medicinal ingredients

Must be chosen from the current Natural health products ingredients database and must meet the limitations outlined in the database.


References cited

References reviewed

Appendix 1: Examples of appropriate dosage preparations and frequencies of use

Dried seed:

1-2 g, per day (Mills and Bone 2005)


1-2 g dried seed, per day (Mills and Bone 2005)



Solid extract:

1.25-2.5 g dried equivalent, 2 times per day
(5-8:1, 0.25-0.31 g) (Blumenthal et al. 2000)

Other extracts: