Chemical Substance - Arbutin
NHPID name:
Arbutin
Reference:
Proper name(s):
Common name(s):
Category:
Approved Chemical Name
Schedule 1:
CAS registry number:
Source material:
- Arctostaphylos uva-ursi ( Parts: Leaf )
- Origanum majorana ( Parts: Leaf )
- Turnera diffusa ( Parts: Leaf )
Roles
Medicinal
Rationale:
Classified as an NHP under Schedule 1, item 2 (an isolate) of the Natural Health Products Regulations.
Reference: NNHPDRestrictions:
Preparation
Upper limit:
2.0
Units:
Route Of administration:
Detail:
Up to 2% in preparations for topical use on the skin.
Reference:
Non-medicinal
Purposes:
Restrictions:
General:
Upper limit:
0.5
Units:
Route Of administration:
Detail:
For topical use only, up to 0.5%.
Reference:
Non-NHP
Rationale:
Arbutin is a derivative of hydroquinone, listed on the Prescription Drug List for human use as follows: Hydroquinone or its derivatives, when sold in a concentration greater than 2% in preparations for topical use on the skin.
Reference: NNHPD