Defined Organism Substance - Origanum Vulgare Leaf Oil
NHPID name:
Origanum Vulgare Leaf Oil
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Approved Herbal Substance Name
Schedule 1:
Source material(s):
Preparations:
Roles
Non-medicinal
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Restrictions:
General:
Detail:
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared. Based on safety concerns, oregano oil intake of up to 0.27 micrograms/kg body weight per day is allowed. Applicants must provide evidence to support the safe use of the carvacrol content of oil of oregano, if they would like to use a higher quantity as a NMI in their product. If the daily exposure of carvacrol exceeds 0.23 micrograms/kg bw per day from the NHP in the absence of adequate safety evidence, the oil of oregano cannot be considered to be a NMI."
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