Chemical Substance - Methylene chloride

NHPID name:
Methylene chloride

Reference:

Proper name(s):

Common name(s):

Category:
Approved Chemical Name

CAS registry number:



Additional details:

Detail:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.


Toxicity restriction:

Upper limit:
6.0

Units:

Detail:
Permitted daily exposure as residual solvent up to 6 mg/day, equivalent to a concentration limit of 6000 ppm when assuming a product mass of 10 g administered daily. This limit applies to all dosage forms and routes of administration.

Related links:

Reference:
ICH


Roles

Non-medicinal

Purposes:
Restrictions:

General:

Detail:
Not permitted in aerosol products.

Reference:
CIH

Date modified: