Chemical Substance - Methylisothiazolinone

NHPID name:
Methylisothiazolinone

Reference:
ICID

Proper name(s):
2-Methyl-3(2H)-isothiazolone

Common name(s):
Methylisothiazolinone

Category:
Approved Chemical Name

CAS registry number:
2682-20-4



Additional details

Detail:
The presence of this ingredient as restricted on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in natural health products, unless additional evidence for safety is submitted.


Roles

Non-medicinal

Purposes:
Preservative Antimicrobial
Restrictions:

Preparation

Upper limit:
0.0015

Units:
Percent

Route Of administration:
Topical

Detail:
For topical use only. Not permitted in leave-on products, and up to 0.0015% in rinse-off products. If methylisothiazolinone (MI) is present in a formulation in combination with methylchloroisothiazolinone (MCI), the cumulative, total concentration of MI and MCI may not exceed 0.0015%.

Reference:
CIH