Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on February 27, 2026.

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ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.


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New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Neosetophoma Cerealis Extract

Role:
Non-medicinal

NHPID Name:
Carboxydecyl Dimethicone

Role:
Non-medicinal

NHPID Name:
Tyrosol

Role:
Medicinal

NHPID Name:
Oenothera Biennis (Evening Primrose) Oil

Role:
Non-medicinal

NHPID Name:
Inland sea salts

Role:
Medicinal

NHPID Name:
Butyrospermum Parkii (Shea) Nut Extract

Role:
Non-medicinal

NHPID Name:
Oleacein

Role:
Medicinal

NHPID Name:
Oleocanthal

Role:
Medicinal

NHPID Name:
Aureobasidium pullulans

Role:
Medicinal

NHPID Name:
Oncorhynchus keta

Role:
Medicinal

NHPID Name:
Undenatured type XI collagen

Role:
No role

NHPID Name:
Undenatured proteoglycan

Role:
No role

NHPID Name:
Bovine Colostrum Whey Permeate

Role:
Medicinal

NHPID Name:
Sialic acids

Role:
No role

NHPID Name:
Dittrichia viscosa

Role:
Medicinal

NHPID Name:
Cera Flava

Role:
Medicinal

NHPID Name:
Marmelosin

Role:
Component

Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

No Changes.


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:
Hydrogenated Cottonseed Oil

New NHPID Name:
Hydrogenated Cottonseed Oil

Old NHPID Name:
Proline-rich polypeptide

New NHPID Name:
Proline-rich polypeptides

Old NHPID Name:
1, 1-Difluoroethane

New NHPID Name:
Hydrofluorocarbon 152a

Old NHPID Name:
Vanilla

New NHPID Name:
Vanilla Dry

Old NHPID Name:
Ethyl vanillin

New NHPID Name:
Ethyl vanillin

Old NHPID Name:
Vanillyl acetate

New NHPID Name:
Vanillin acetate

Revised Common or Proper Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
PhEur_Apis mellifera

New Proper Name(s):
Apis mellifica

NHPID Name:
Evening Primrose Oil

Removed Common Name(s):
Oenothera biennis (Evening primrose) oil

NHPID Name:
Hydrogenated Cottonseed Oil

Removed Proper Name(s):
Hydrogenated Cottonseed Oil

NHPID Name:
Hydrogenated Cottonseed Oil

New Proper Name(s):
Cottonseed oil, hydrogenated

NHPID Name:
Hydrogenated Cottonseed Oil

Removed Common Name(s):
CottonSeed Oil-Hydrogenated

NHPID Name:
Hydrogenated Cottonseed Oil

New Common Name(s):
Hydrogenated cottonseed oil

NHPID Name:
Concha Ostreae

New Proper Name(s):
Magallana rivularis

NHPID Name:
Proline-rich polypeptides

Removed Proper Name(s):
Proline-rich polypeptide

NHPID Name:
Proline-rich polypeptides

Removed Common Name(s):
Proline-rich polypeptide

NHPID Name:
Proline-rich polypeptides

New Common Name(s):
Proline-rich polypeptides

NHPID Name:
Proline-rich polypeptides

New Proper Name(s):
Proline-rich polypeptides

NHPID Name:
Ephedra sinica

Removed Common Name(s):
Chinese ephedra ; Ephedra

NHPID Name:
Ephedra sinica

New Common Name(s):
Chinese ephedra ; Ephedra

NHPID Name:
Hydrofluorocarbon 152a

Removed Proper Name(s):
1, 1-Difluoroethane

NHPID Name:
Hydrofluorocarbon 152a

Removed Common Name(s):
1, 1-Difluoroethane

NHPID Name:
Hydrofluorocarbon 152a

New Proper Name(s):
1,1-Difluoroethane

NHPID Name:
Hydrofluorocarbon 152a

New Common Name(s):
1,1-Difluoroethane ; Hydrofluorocarbon 152a

NHPID Name:
Nicotine

Removed Proper Name(s):
1-Methyl-2-(3-pyridyl)pyrrolidine ; 3-(1-Methyl-2-pyrrolidinyl)pyridine ; 3-[(2S)-1-Methyl-2-pyrrolidinyl]pyridine ; beta-Pyridyl-alpha-N-methyl pyrrolidine

NHPID Name:
Nicotine

New Proper Name(s):
3-[(2S)-1-Methyl-2-pyrrolidinyl]pyridine

NHPID Name:
Hydrated silica

Removed Proper Name(s):
Hydrated Silica

NHPID Name:
Hydrated silica

New Proper Name(s):
Silicic acid hydrate

NHPID Name:
Hydrated silica

Removed Common Name(s):
Silicon Dioxide Hydrate

NHPID Name:
Hydrated silica

New Common Name(s):
Silicon dioxide hydrate

NHPID Name:
l-Ephedrine

New Common Name(s):
Ephedrine

NHPID Name:
Vanillin

Removed Proper Name(s):
Methyl protocatechuic aldehyde

NHPID Name:
Vanilla Powder

New Common Name(s):
Vanilla

NHPID Name:
Vanilla Dry

New Common Name(s):
Vanilla dry

NHPID Name:
Ethyl vanillin

Removed Common Name(s):
Ethyl vanillin

NHPID Name:
Ethyl vanillin

New Common Name(s):
Ethyl vanillin

NHPID Name:
Vanillin acetate

New Proper Name(s):
3-Methoxy-4-acetoxybenzaldehyde

NHPID Name:
Vanillin acetate

Removed Proper Name(s):
Vanillyl acetate

NHPID Name:
Vanillin acetate

Removed Common Name(s):
(4-formyl-2-methoxy-phenyl) acetate ; 3-Methoxy-4-acetoxybenzaldehyde ; 4-acetoxy-3-methoxybenzaldehyde ; 4-Formyl-2-methoxyphenyl acetate ; Acetylvanillin ; Acetyl vanillin ; Benzaldehyde, 4-(acetyloxy)-3-methoxy- ; Vanillin, acetate

NHPID Name:
Vanillyl alcohol

Removed Proper Name(s):
Vanillyl Alcohol

NHPID Name:
Vanillyl alcohol

New Proper Name(s):
4-Hydroxy-3-methoxybenzyl alcohol

NHPID Name:
Vanillyl alcohol

Removed Common Name(s):
4-(hydroxymethyl)-2-methoxy-phenol ; 4-Hydroxy-3-methoxybenzenemethanol ; 4-Hydroxy-3-methoxybenzyl alcohol ; Benzenemethanol, 4-hydroxy-3-methoxy-

NHPID Name:
Vanillyl alcohol

New Common Name(s):
Vanillyl alcohol

Changed Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
Evening Primrose Oil

Old Role:
Medicinal & Non-medicinal

New Role:
Medicinal

NHPID Name:
Proline-rich polypeptides

Old Role:
Medicinal

New Role:
No role

Restriction Modifications

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Oleyl Alcohol

New Non-medicinal Restriction(s) added:
For topical use only, up to 18%.

NHPID Name:
Inland sea water

Medicinal Rationale Changed:
Classified as an NHP under Schedule 1, item 2 (an extract) of the Natural Health Products Regulations.

NHPID Name:
Sea salt

New Non-medicinal Restriction(s) added:
For topical use only.

NHPID Name:
Benzoic acid

Non-medicinal Restriction(s) changed:
Up to 5%.

NHPID Name:
Benzoic acid

New Non-medicinal Restriction(s) added:
New Route of Administration : Oral

NHPID Name:
Hydrogenated Cottonseed Oil

New Non-medicinal Restriction(s) added:
Up to 24%.

NHPID Name:
Propylene Glycol Dibenzoate

Non-medicinal Restriction(s) removed:
For oral use only.

NHPID Name:
Radix et Rhizoma Ephedrae

New Medicinal Restriction(s) added:
In all products containing Ephedra species, the content of L-Ephedrine and its salts must not exceed 8 - 32 milligrams per day and 8 milligrams per single dose.

NHPID Name:
Hydrofluorocarbon 152a

Non-medicinal Restriction(s) removed:
Topical use only. Propellant only.

NHPID Name:
Nicotine

Medicinal Rationale Changed:
Classified as an NHP under Schedule 1, item 2 (an isolate) of the Natural Health Products Regulations when the following conditions are met: a. in natural substances; b. in the form of a chewing gum containing 4 milligrams or less of nicotine per dosage unit; c. in the form of a transdermal patch with a delivery rate of 22 milligrams or less of nicotine per day; d. in the form of a spray or inhaler (namely, non-active devices operating on energy generated by the human body or gravity) that delivers 4 milligrams or less of nicotine per dosage unit into the oral cavity for buccal absorption; e. in the form of a lozenge containing 4 milligrams or less of nicotine per dosage unit; f. in the form of a buccal pouch containing 4 milligrams or less of nicotine per dosage unit; or g. in the form of an orally disintegrating or sublingual tablet containing 4 milligrams or less of nicotine per dosage unit for buccal absorption.

NHPID Name:
Vanilla Powder

New Non-medicinal Restriction(s) added:
For oral use only.

NHPID Name:
Vanilla Dry

New Non-medicinal Restriction(s) added:
For oral use only.

Other Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Oleyl Alcohol

Removed NMI purpose(s):
Solubilizing Agent

NHPID Name:
Oleyl Alcohol

New NMI Purpose(s):
Dissolution Enhancing Agent ; Skin-Conditioning Agent - Emollient

NHPID Name:
Chlorophyll

New Source Material(s) added:
Auxenochlorella pyrenoidosa (Parts: Broken cell)

NHPID Name:
Auxenochlorella pyrenoidosa

New Sub-ingredient(s) added:
Chlorophyll

NHPID Name:
Chloride

New Source Ingredient(s) added:
Inland sea salts

NHPID Name:
Magnesium

New Source Ingredient(s) added:
Inland sea salts

NHPID Name:
Potassium

New Source Ingredient(s) added:
Inland sea salts

NHPID Name:
Sodium

New Source Ingredient(s) added:
Inland sea salts

NHPID Name:
Inland sea water

Revised Schedule 1:
Extract

NHPID Name:
Sea salt

New Additional Details added:
Prescription Drug List substances that occur naturally must be present in no more than trace levels with no therapeutic effect or toxicological concern. Applicants will have to provide supporting quantitative analytical evidence and evidence to support safety of the component at that level.

NHPID Name:
Sea salt

Removed NMI purpose(s):
Flavour Enhancer ; Lubricant ; Tonicity Agent

NHPID Name:
Sodium Chloride

New NMI Purpose(s):
Lubricant

NHPID Name:
Benzoic acid

New NMI Purpose(s):
PH Adjuster

NHPID Name:
Hydrogenated Cottonseed Oil

Modification:
Removed Other Registry Numbers : 53026-92-9 ; 68562-65-2

NHPID Name:
Fisetin

New Source Material(s) added:
Rhus succedanea (Parts: Stem)

NHPID Name:
Olea europaea

New Sub-ingredient(s) added:
Oleacein ; Oleocanthal ; Tyrosol

NHPID Name:
beta-1,3/1,6-Glucan

New Source Material(s) added:
Aureobasidium pullulans (Parts: Whole)

NHPID Name:
Undenatured type II collagen

New Source Material(s) added:
Oncorhynchus keta (Parts: Cartilage)

NHPID Name:
Concha Ostreae

New Source Material(s) added:
Magallana rivularis (Parts: Shell)

NHPID Name:
Propylene Glycol Dibenzoate

New NMI Purpose(s):
Skin-Conditioning Agent - Emollient

NHPID Name:
Proline-rich polypeptides

New Source Material(s) added:
Bos taurus (Parts: Colostrum)

NHPID Name:
Pseudoephedrine

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra antisyphilitica

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra equisetina

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra gerardiana

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra intermedia

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra nevadensis

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra sinica

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra viridis

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Ephedra vulgaris

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Herba Ephedrae

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Radix et Rhizoma Ephedrae

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Precursor Control Regulations because it is set out in Schedule VI of the Controlled Drugs and Substances Act.

NHPID Name:
Hydrofluorocarbon 152a

New Additional Details added:
It should be noted that this substance is subject to additional regulatory requirements in accordance with the Environmental Emergency Regulations and the Ozone-depleting Substances and Halocarbon Alternatives Regulations.

NHPID Name:
Beeswax, White

Removed Schedule 1:
Non-human animal material

NHPID Name:
Beeswax, Yellow

Removed Schedule 1:
Non-human animal material

NHPID Name:
Aegle marmelos

New Sub-ingredient(s) added:
Marmelosin

NHPID Name:
Hydrated silica

New Sub-ingredient(s) added:
Silicon dioxide

NHPID Name:
Silicon dioxide

New Source Ingredient(s) added:
Hydrated silica

NHPID Name:
Vanillin

Toxicity Restriction removed:
Acceptable daily intake up to 10 mg/kg body weight daily.

NHPID Name:
Vanilla Extract

Removed Schedule 1:
Plant and plant material

NHPID Name:
Vanilla Powder

Removed Schedule 1:
Plant and plant material

NHPID Name:
Vanilla Powder

Additional Details removed:
Acceptable daily intake of vanillin is up to 10 mg/kg body weight. Reference: JECFA. http://www.inchem.org/documents/jecfa/jeceval/jec_2380.htm

NHPID Name:
Vanilla Dry

Removed Schedule 1:
Plant and plant material

NHPID Name:
Vanilla Dry

Additional Details removed:
Acceptable daily intake of vanillin is up to 10 mg/kg body weight. Reference: JECFA. http://www.inchem.org/documents/jecfa/jeceval/jec_2380.htm

NHPID Name:
Ethyl vanillin

Toxicity Restriction removed:
Acceptable daily intake up to 10mg/kg body weight daily (JECFA)

NHPID Name:
Vanillin acetate

Toxicity Restriction removed:
Flavouring agent only; acceptable daily intake up to 10 mg/kg body weight daily (JECFA 1967).

NHPID Name:
Vanillyl alcohol

Toxicity Restriction removed:
Flavouring agent only; acceptable daily intake up to 10 mg/kg body weight daily (JECFA 1967)

Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

Revised:
Heal-all - Prunella Vulgaris - Buccal and Oromucosal

Revised:
Heal-all - Prunella Vulgaris - Oral

Revised:
Witch Hazel - Hamamelis Virginiana - Ophthalmic

Revised:
Witch Hazel - Hamamelis Virginiana - Oral

Revised:
Witch Hazel - Hamamelis Virginiana - Topical

Revised:
Ephedra

Revised:
Evening Primrose Oil

Revised:
Holy Basil - Ocimum Tenuliflorun - Seed

Revised:
Horse Chestnut

Revised:
Homeopathy

Revised:
Ephedrine, L-

Revised:
Peppermint

Revised:
Pomegranate

Revised:
Phosphatidylserine

Revised:
Royal Jelly

Revised:
Red Wine Extract

Revised:
Secondary Sunscreen Monograph

Revised:
Holy Basil - Ocimum Tenuliflorum - Leaf

Revised:
Primary Sunscreen Monograph

Revised:
Witch Hazel - Hamamelis Virginiana Buccal and Oromucosal

Abbreviated Labelling Standards

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Updates

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

Category:
Dosage Forms

Removed:
Pessary

Category:
Dosage Forms

New:
Pessary

Category:
Dosage Forms

Removed Synonym(s):
Ovule

Homeopathic Ingredient Updates

In this update, the following homeopathic ingredients were added or modified.

No Changes.


Previous What's New

Links to previous What's New pages.


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