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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.



January 28, 2022

Proper name(s), Common name(s), Source information

Table 1. Proper name(s), Common name(s), Source information
Proper name(s) Common name(s) Source information
Source material(s) Part(s) Preparation(s)

Hamamelis virginiana

  • Hamamelis
  • Spotted alder
  • Winter bloom
  • Witchazel
  • Witch-hazel

Hamamelis virginiana

  • Bark
  • Leaf


References: Proper name: USDA 2019; Common names: Bradley 2006, ESCOP 2003, McGuffin et al. 2000; Source information: Bradley 2006, ESCOP 2003.

Route of Administration


Dosage Form(s)

This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.

Acceptable dosage forms for oral use are indicated in the dosage form drop-down list of the web-based Product Licence Application form for Compendial applications.

Use(s) or Purpose(s)

Back or Leaf

(Traditionally) used in Herbal Medicine (as an astringent) to help relieve diarrhoea (Bradley 2006; Blumenthal et al. 2000; Ellingwood 1983; Grieve 1971).

Leaf only

(Traditionally) used in Herbal Medicine (as an astringent) to help relieve symptoms associated with varicose veins (such as painful and heavy legs) (ESCOP 2003; Hoffmann 2003; Felter 1983).


Claims for traditional use must include the term "Herbal Medicine", "Traditional Chinese Medicine", or "Ayurveda".



Adults 18 years and older


Methods of preparation: Dry, Powdered, Non-Standardized Extracts (Dry extract, Tincture, Fluid extract, Decoction, Infusion)


0.6 - 9 grams of dried bark, per day (Bradley 2006; ESCOP 2003; Blumenthal et al. 2000; Mills and Bone 2000)


1.2 - 12 grams of dried leaf, per day (Bradley 2006; ESCOP 2003; Blumenthal et al. 2000; Mills and Bone 2000)

Direction(s) for use

Take a few hours before or after taking minerals and/or B-vitamin supplements (Brinker 2008; Mills and Bone 2000).

Duration(s) of Use

No statement required.

Risk Information

Caution(s) and warning(s)


No statement required

Known adverse reaction(s)

Some people may experience gastric irritation (ESCOP 2003; Berardi et al. 2002; Mills and Bone 2000; McGuffin et al. 1997).

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredients Database (NHPID) and must meet the limitations outlined in the database.

Storage conditions

Must be established in accordance with the requirements described in the Natural Health Products Regulations (NHPR).


References cited

References reviewed