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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.



June 3 2019

Proper name(s), Common name(s), Source material(s)

Table 1. Proper name(s), Common name(s), Source material(s)
Proper name(s) Common name(s) Source material(s)
Proper name(s) Part(s) Preparation

Urtica dioica

  • Common nettle
  • European nettle
  • Greater nettle
  • Nettle
  • Stinging nettle
  • Yi zhu qian ma

Urtica dioica

  • Herb top
  • Root


References: Proper name: USDA 2019; Common names: Blumenthal et al. 2000; McGuffin et al. 2000; Source materials: ESCOP 2003; Wren 1907.

Route of Administration


Dosage Form(s)

This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.

Acceptable dosage forms for any age category listed in this monograph for the specified route of administration are listed in the Compendium of Monographs Guidance Document.

Use(s) or Purpose(s)

Herb top


Used in Herbal Medicine to help reduce difficulty in urination associated with the early stages of benign prostatic hyperplasia (BPH) (Bradley 2006; Mills and Bone 2005; ESCOP 2003; Hoffmann 2003; Blumenthal et al. 2000).

Claims for traditional use must include the term "Herbal Medicine", "Traditional Chinese Medicine", or "Ayurveda".



Adults 18 years and older


Methods of preparation: Dry, Powder, Non-Standardized Extracts (Dry extract, Tincture, Fluid extract, Decoction, Infusion)

Herb top

1.2 - 18 grams of dried herb tops, per day (Mills and Bone 2005; ESCOP 2003; Hoffman 2003; Blumenthal et al. 2000; Bradley 1992)


0.3 - 24 grams of dried root, per day (Bradley 2006; Mills and Bone 2005; ESCOP 2003; Hoffman 2003; Blumenthal et al. 2000)

Direction(s) for use

No statement required.

Duration(s) of Use


For occasional use only (Berardi et al. 2002; CPA 2002)

Risk Information

Caution(s) and warning(s)

All products except nutritive tonics

Consult a health care practitioner/health care provider/health care professional/doctor/physician if symptoms persist or worsen.


Do not use this product if you are pregnant or breastfeeding (Barnes et al. 2007; Brinker 2001; Tilgner 1999).

Known adverse reaction(s)

No statement required.

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredients Database (NHPID) and must meet the limitations outlined in the database.

Storage conditions

No statement required.


References Cited