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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.



August 28, 2018

Proper name(s), Common name(s), Source material(s)

Table 1. Proper name(s), Common name(s), Source material(s)
Proper name(s) Common name(s) Source material(s)
Proper name(s) Part(s)

Vitis vinifera

  • Red Wine Extract
  • Red Wine Polyphenol Extract

Vitis vinifera


References: Proper name: USDA 2018; Common names: Leifert and Abeywardena 2008; Source material: Nigdikar et al. 1998, Brouillard et al. 1997.

Route of Administration


Dosage Form(s)

This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.

Acceptable dosage forms for the age category listed in this monograph and specified route of administration are indicated in the Compendium of Monographs Guidance Document.

Use(s) or Purpose(s)

Source of/Provides antioxidants (Meskin et al. 2002; Cuevas et al. 2000).



Adults 18 years and older


Methods of preparation: Standardized or Non-Standardized Extracts (Dry extract, Tincture, Fluid extract, Decoction, Infusion)

Not to exceed 1 gram of red wine extract, per day (Chopra et al. 2000; Cuevas et al. 2000; Nigdikar et al. 1998).

Potency (Optional): Not to exceed 95% polyphenols (Botden et al. 2012; Chopra et al. 2000).

Direction(s) for use

No statement required.

Duration(s) of Use

No statement required.

Risk Information

Caution(s) and warning(s)

Consult a health care practitioner/health care provider/health care professional/doctor/physician prior to use if you are pregnant or breastfeeding (Meskin et al. 2002).


No statement required.

Known adverse reaction(s)

No statement required.

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredients Database (NHPID) and must meet the limitations outlined in the database.

Storage conditions

No statement required.


References cited

References reviewed