QUERCETIN

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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.

Notes

Date

June 3, 2019

Proper name(s), Common name(s), Source material(s)

Table 1. Proper name(s), Common name(s), Source material(s)
Proper name(s) Common name(s) Source ingredient(s)
Common name(s)
  • 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
  • 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
  • 3,3´,4´,5,7-Pentahydroxyflavone
  • Quercetin
  • Quercetin anhydrous
  • Citrus bioflavonoids
  • Quercetin
  • Quercetin dihydrate

References: Proper names: Ph.Eur. 2013, ChemID 2012, Merck 2012, PubChem 2012, Martindale 2011; Common names: ChemID 2012; Merck 2012; Source ingredients: NHPID 2019.

Route of Administration

Oral

Dosage Form(s)

This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.

Acceptable dosage forms for any age category listed in this monograph for the specified route of administration are listed in the Compendium of Monographs Guidance Document.

Use(s) or Purpose(s)

Dose(s)

Subpopulation(s)

Adults 18 years and older

Quantity(ies)

Antioxidant

Not to exceed 1,200 milligrams of Quercetin, per day and 600 milligrams per single dose (NS 2012; Wang et al. 2009; Boots et al. 2008; PDR 2008; Erlund et al. 2003; Lamson and Brignall 2000; Hakkinen et al. 1999).

Capillary/ blood vessel protectant

600 - 1,200 milligrams of Quercetin, per day. Not to exceed 600 milligrams per single dose (PDR 2008; Murray and Bongiorno 2006).

Direction(s) for use

Products providing 40-1,200 milligrams of Quercetin, per day

Take with food/meal (Harwood et al. 2007).

Duration(s) of Use

Products providing 40-1,200 milligrams of Quercetin, per day

Consult a health care practitioner/health care provider/health care professional/doctor/physician for use beyond 12 weeks (NS 2012; Harwood et al. 2007; Boyle et al. 2000).

Risk Information

Caution(s) and warning(s)

Products providing 40-1,200 milligrams of Quercetin, per day

Consult a health care practitioner/health care provider/health care professional/doctor/physician prior to use if you are pregnant or breastfeeding.

Contraindication(s)

No statement required.

Known adverse reaction(s)

No statement required.

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredients Database (NHPID) and must meet the limitations outlined in the database.

Storage conditions

Store in a light-resistant container (Ph.Eur. 2013).

Specifications

References Cited

References Reviewed