Nosodes
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(PDF Version - 157 K)This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredients.
Notes
- Text in parentheses is additional optional information which can be included on the PLA and product label at the applicant's discretion.
- The solidus (/) indicates that the terms and/or the statements are synonymous. Either term or statement may be selected by the applicant.
- Use of the electronic Product License Application form (ePLA) is not possible for products associated with this monograph.
Date
July 16, 2015
Proper name(s) and Common name(s)
| Proper name(s) | Common name(s) |
|---|---|
| Anthracinum; Bacillus anthracis | Anthracinum; Bacillus anthracis; Bacteridium anthracis |
| Aspergillus niger | Aspergillus niger |
| Bacille of Morgan; Morganella morgannii | Bacille of Morgan; Morgan; Morganella morganii |
| Bacillinum pulmo | Bacillinum pulmo |
| BCG | BCG |
| Botulinum | Botulinum; Clostridium botulinum |
| Calcarea renalis | Calcarea renalis; Lapis renalis; Renal calculi |
| Candida albicans | Candida albicans; Monilla albicans |
| Candida parapsilosis | Candida parapsilosis; Candida parakrusei; Monilla parapsilosis |
| Carcinosin | Carcinosin |
| Chlamydia trachomatis | Chlamydia trachomatis; Chlamydozoon trachomatis; Rickettsia trachomae; Rickettsia trachomatis |
| Colibacillinum cum natrum muriaticum | Colibacillinum cum natrum muriaticum; Escherichia coli in isotonic sodium chloride solution |
| Ophiocordyceps sinensis | Ophiocordyceps sinensis; Cordyceps; Chinese Caterpillar Fungus; Dong Chong Xia Cao |
| Coxsackie | Coxsackie |
| Diphtherinum | Diphtherinum; Potentized diphtheritic microbe; Corynebacterium diphtheriae |
| Eberthinum | Eberthinum; Salmonella typhosa; Eberthella typhosa |
| Enterococcinum | Enterococcinum; Mixed Enterococcus/Streptococcus stock |
| Epstein-Barr | Epstein-Barr Virus; HHV-4 |
| Friedlander Bacillus of Pneumonia; Klebsiella pneumoniae | Friedlander Bacillus of Pneumonia; Klebsiella pneumoniae; Bacillus mucosus capsulatus; Friedlander; Pneumobacillus |
| Herpes simplex | Herpes Simplex |
| Herpes zoster | Herpes Zoster |
| Hippozaeninum; Hippozaenin | Hippozaeninum; Hippozaenin; Farcin; Farcine; Glanderin; Glanderine; Mallein |
| Influenzinum; Influenza virus | Influenzinum; Influenza virus; Vaccinum influenzae inactivum; Influenza; Inactivated influenza |
| Lyssin | Lyssin; Hydrophobinum |
| Malandrinum | Malandrinum |
| Malaria officinalis | Malaria officinalis |
| Marmorek | Marmorek |
| Medorrhinum | Medorrhinum; Glinicum; Gonorrhoeal virus; Neisseria gonorrhoeae |
| Meningococcinum | Meningococcinum; Neisseria meningitidis |
| Micrococcus tetragenus (Must be combined with Friedlander Bacillus of Pneumonia AND Mucotoxin) | Peptostreptococcus tetradius |
| Mucotoxin | Mucotoxin; Micrococcus catarrhalis |
| Mononucleosis | Mononucleosis |
| Morbilinum | Morbilinum |
| Mucor mucedo | Mucor mucedo |
| Ourlianum | Ourlianum |
| Pertussinum | Pertussinum; Pertussin; Coqueluchin; Coqueluchinum |
| Pneumococcinum | Pneumococcinum |
| Poliomyelitis | Poliomyelitis |
| Proteus; Proteus inconstans; Proteus mirabilis; Proteus morgani; Proteus rettgeri; Proteus vulgaris | Proteus; Proteus inconstans; Proteus mirabilis; Proteus morgani; Proteus rettgeri; Proteus vulgaris |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa; Pseudomonas |
| Psorinum | Psorinum; Psoricum |
| Pyrogenium; Pyrogen | Pyrogenium; Pyrogen |
| Salmonella typhi | Salmonella typhi |
| Scarlatinum; Streptococcus pyogenes | Scarlatinum; Streptococcus pyogenes |
| Sinusitisinum | Sinusitisinum; Sinusitis nosode; Maxillary sinusitis nosode |
| Staphylococcinum; Staphylococcus; Staphylococcus aureus | Staphylococcinum; Staphylococcus; Staphylococcus aureus; Staph; |
| Staphylotoxinum | Staphylotoxinum |
| Streptococcinum; Streptococcus pyogenes | Streptococcinum; Streptococcus pyogenes; Streptococcin; Pyogenic streptococcus |
| Syphilinum | Syphilinum; Luesinum; Lueticum |
| Tetanotoxicum | Tetanotoxicum |
| Tuberculinum; Tuberculin | Tuberculinum; Tuberculin; Tuberculinum crudum; Old tuberculin |
| Tuberculinum bovinum; Bovine tuberculin | Tuberculinum bovinum; Bovine tuberculin |
| Vaccinotoxinum; Smallpox | Vaccinotoxinum; Smallpox; Vaccininum; variolae fluidum |
| Variolinum | Variolinum |
Source materials
Please refer to Appendix I.
Route(s) of administration
- Oral
- Sublingual
- Nasal
- Ophthalmic
- Topical
- Rectal
Dosage form(s)
Those pharmaceutical dosage forms suited to the routes of administration.
Use(s) or Purpose(s)
Statement(s) to the effect of
Nosodes preparation/remedy/medicine
Dose(s)
Statement(s) to the effect of
Subpopulation(s)
Adults (≥ 18 years) and adolescents (13-17 years)
Quantity(ies)
Note: The minimum homeopathic potency for each medicinal ingredient is listed in Appendix I.
| Dosage form | Maximum General Dosing | Maximum Acute Dosing | |
|---|---|---|---|
| Amount | Frequency | ||
| Globules (small pellets, pilules) | 1 whole unit dose (tube or container) | Once per day | 20 globules, 3 times per day |
| Granules (regular and large pellets) | 5 granules | 3 times per day | Every 15-60 minutes (up to 12 times per day) or until improvement of symptoms. Then resume general dosing. |
| Tablets | 4 tablets | 4 times per day | Every 15-60 minutes (up to 12 times per day) or until improvement of symptoms. Then resume general dosing. |
| Oral Drops | 30 drops | 3 times per day | Every 15-60 minutes (up to 12 times per day) or until improvement of symptoms. Then resume general dosing |
| Liquid (Oral drinkable vials) | 1 ampoule | 3 times per day | Up to three times per day. |
| Oral Solution (unit dose) | 1 unit dose | 3 times per day | Give one unit dose upon onset of symptoms. Repeat two more times at 15-minute intervals. Repeat process up to 9 times per day if symptoms reappear. |
| Oral Syrup | 1-2 tsp | Every 4-6 hours | Not applicable |
| Cream/Ointment | Cover affected area | As needed | Not applicable |
| Nasal spray | 2 sprays per nostril | 5 times per day | Not applicable |
| Suppositories | 1 suppository | 1-4 times per day | Maximum 4 times per day |
Method of preparation
The method of preparation must be one of the following:
- HPUS Class I (Nosodes)
- HAB Method 43 or 44 or 58a or 58b (Nosodes)
Directions of use
Take as directed by a health care practitioner.
Duration of use
Statement(s) to the effect of
No statement required.
Risk information
Statement(s) to the effect of
Caution(s) and warning(s)
- If symptoms persist or worsen, consult a health care practitioner.
- If you are pregnant or breastfeeding, consult a health care practitioner prior to use.
Contraindication(s)
This product is neither a vaccine nor an alternative to vaccination. This product has not been proven to prevent infection. Health Canada does not recommend its use in children and advises that your child receive all routine vaccinations.
Known adverse reaction(s)
No statement required.
Non-medicinal ingredients
Must be chosen from the current Natural Health Products Ingredients Database NHPID and must meet the limitations outlined in the database.
Specifications
- The finished product specifications must be established in accordance with the requirements described in the Natural and Non-Prescription Health Products Directorate Quality of Natural Health Products Guide.
- The medicinal ingredient must comply with the requirements outlined in the NHPID .
References cited
Homeopathic Pharmacopeia of the United States (HPUS).
References reviewed
- Encyclopedia of Homeopathic Pharmacopoeia (EHP).
- Frans Vermeulen. Monera: Kingdom Bacteria and Viruses. Spectrum Materia Medica. Volume 1, Netherlands.
- Frans Vermeulen. Fungi: Kingdom Fungi. Spectrum Materia Medica. Volume 2, Netherlands.
- Hans-Heinrich Reckeweg. Materia Medica. Homoeopathia Antihomotoxica. Volume I. A Selective Pharmacology.
- Robin Murphy. 1996. Lotus Materia Medica.
- Rajkumar Mukherji. 2005. Julian's Materia Medica of Nosodes with Repertory. Treatise on Dynamised Micro-immnunotherapy.
- William Boericke. Pocket Manual of Homoeopathic Materia Medica. 9th Ed.
Appendix I
| Proper name | Common name | Quantity | Source Material |
|---|---|---|---|
| Anthracinum; Bacillus anthracis | Anthracinum; Bacillus anthracis; Bacteridium anthracis | 6X | Sterilized lysate of liver of rabbit infected with Bacillus anthracis |
| Aspergillus niger | Aspergillus niger | 12CH | Black mould |
| Bacille of Morgan; Morganella morgannii | Bacille of Morgan; Morgan; Morganella morganii | 12CH | Bacteria isolated from faeces of man |
| Bacillinum pulmo | Bacillinum pulmo | 12CH | Bacteria isolated from human lung tissue infected with Mycobacterium tuberculosis or Mycobacterium bovis |
| BCG | BCG | 12CH | Dried living culture of Mycobacterium tuberculosis var. bovis |
| Botulinum | Botulinum; Clostridium botulinum | 12CH | Bacteria isolated from contaminated food with with Clostridium botulinum |
| Calcarea renalis | Calcarea renalis; Lapis renalis; Renal calculi | 12CH | Renal calculi |
| Candida albicans | Candida albicans; Monilla albicans | 12X | Yeast cells from digestive system of man and animals |
| Candida parapsilosis | Candida parapsilosis; Candida parakrusei; Monilla parapsilosis | 12X | Yeast cells from digestive system of man and animals |
| Carcinosin | Carcinosin | 12CH | Cancer nosode from carcinoma |
| Chlamydia trachomatis | Chlamydia trachomatis; Chlamydozoon trachomatis; Rickettsia trachomae; Rickettsia trachomatis | 12CH | Chlamydia trachomatis |
| Colibacillinum cum natrum muriaticum | Colibacillinum cum natrum muriaticum; Escherichia coli in isotonic sodium chloride solution | 8X | Sterilized suspension of Escherichia coli in isotonic sodium chloride |
| Ophiocordyceps sinensis | Ophiocordyceps sinensis; Cordyceps; Chinese Caterpillar Fungus; Dong Chong Xia Cao | 12CH | Ophiocordyceps sinensis (fungus) |
| Coxsackie | Coxsackie | 12CH | Inactivated Coxsackie viruses of sub-groups A9 and B4 |
| Diphtherinum | Diphtherinum; Potentized diphtheritic microbe; Corynebacterium diphtheriae | 12CH | Diphtheria infected membrane |
| Eberthinum | Eberthinum; Salmonella typhosa; Eberthella typhosa | 12CH | Stools from patients suffering from typhoid |
| Enterococcinum | Enterococcinum; Mixed Enterococcus/Streptococcus stock | 12CH | Mixed Enterococcus/Streptococcus stock |
| Epstein barr | Epstein Barr Virus; HHV-4 | 12CH | Epstein-Barr Virus |
| Friedlander Bacillus of Pneumonia; Klebsiella pneumoniae | Friedlander Bacillus of Pneumonia; Klebsiella pneumoniae; Bacillus mucosus capsulatus; Friedlander; Pneumobacillus | 12CH | Bacteria isolated from the bowel of man, soil, and/or water |
| Herpes simplex | Herpes Simplex | 12CH | Herpes simplex secretion obtained by opening the vesicles |
| Herpes zoster | Herpes Zoster | 12CH | Excretion obtained from shingles vesicles in various locations and at various stages |
| Hippozaeninum; Hippozaenin | Hippozaeninum; Hippozaenin; Farcin; Farcine; Glanderin; Glanderine; Mallein | 12CH | Discharge from nose or skin lesions of untreated equine animals or humans with Pseudomonas mallei |
| Influenzinum; Influenza virus | Influenzinum; Influenza virus; influenzae inactivum; Influenza; Inactivated influenza | 8X | Inactivated influenza virus type A and B individually or combined, from chicken embryo |
| Lyssin | Lyssin; Hydrophobinum | 12CH | Saliva of rabid dog |
| Malandrinum | Malandrinum | 12CH | Malanders (psoriasis of the bend of knees) of the horse |
| Malaria officinalis | Malaria officinalis | 12CH | Dissolved gases from decomposed vegetable matter taken from marshes when malaria toxin is most active |
| Marmorek | Marmorek | 12CH | Serum of tuberculosis induced in the horses |
| Medorrhinum | Medorrhinum; Glinicum; Gonorrhoeal virus; Neisseria genethceae | 12CH | Purulent urethral secretions containing Neisseria gonorrhoeae |
| Meningococcinum | Meningococcinum; Neisseria meningitidis | 12CH | Bacteria isolated from cerebral fluid of patients with meningitis |
| Micrococcus tetragenus (Must be combined with Friedlander Bacillus of Pneumonia AND Mucotoxin) | Peptostreptococcus tetradius | 12CH | Lysate of culture of Mucotoxin, Friedlander Bacillus of Pneumonia and Micrococcus tetragenus |
| Mucotoxin | Mucotoxin; Micrococcus catarrhalis | 12CH | Bacteria isolated from nasal discharge of patients suffering from pneumonia-like catarrh |
| Mononucleosis | Mononucleosis | 12CH | Saliva from patients infected with Pfeiffer's disease (Mononucleosis) caused by the Epstein Barr Virus |
| Morbilinum | Morbilinum | 12CH | Buccopharyngeal exudates from humans infected with measles |
| Mucor mucedo | Mucor mucedo | 12CH | Whole fungus |
| Ourlianum | Ourlianum | 12CH | Lysate from the saliva of patients suffering from mumps |
| Pertussinum | Pertussinum; Pertussin; Coqueluchin; Coqueluchinum | 12CH | Sterilized lysate of the expectoration of untreated patients infected by Bordetella pertussin |
| Pneumococcinum | Pneumococcinum | 12CH | Bacteria extracted from the saliva, nasal mucosa, mucosa of pharynx and conjunctiva of healthy person |
| Poliomyelitis | Poliomyelitis | 12CH | Cerebrospinal fluid of poliomyelitis patients, obtained by lumbar puncture |
| Proteus; Proteus inconstans; Proteus mirabilis; Proteus morgani; Proteus rettgeri; Proteus vulgaris | Proteus; Proteus inconstans; Proteus mirabilis; Proteus morgani; Proteus rettgeri; Proteus vulgaris | 12CH | Enterobacteria isolated from patients with gastroenteritis and urinary tract infections |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa; Pseudomonas | 12CH | Pseudomonas aeruginosa |
| Psorinum | Psorinum; Psoricum | 12CH | Serous fluids from scabies lesions caused by itch mite Sarcoptes scabiei of untreated patients |
| Pyrogenium; Pyrogen | Pyrogenium; Pyrogen | 12X | Lysate of ox flesh |
| Salmonella typhi | Salmonella typhi | 12CH | Washings of a culture of Salmonella typhi |
| Scarlatinum; Streptococcus pyogenes | Scarlatinum; Streptococcus pyogenes | 12CH | Whole bacteria sourced from man, animals, skin or air |
| Sinusitisinum | Sinusitisinum; Sinusitis nosode; Maxillary sinusitis nosode | 12X | Mucous substances from inflamed sinus cavities of patients with acute sinusitis maxillaries |
| Staphylococcinum; Staphylococcus; Staphylococcus aureus | Staphylococcinum; Staphylococcus; Staphylococcus aureus; Staph | 12CH | Sourced from mixed culture of Staphylococcus epidermidis, Staphylococcus haemolyticus, and Staphylococcus simulans |
| Staphylotoxinum | Staphylotoxinum | 12CH | Anatoxin of staphylococcus |
| Streptococcinum; Streptococcus pyogenes | Streptococcinum; Streptococcus pyogenes; Streptococcin; Pyogenic streptococcus | 12CH | From pure cultures of Streptococcus pyogenes free from antimicrobial agents |
| Syphilinum | Syphilinum; Luesinum; Lueticum | 12CH | Extractions from syphlitic cankers of untreated patients |
| Tetanotoxicum | Tetanotoxicum | 12CH | Tetanus toxin |
| Tuberculinum; Tuberculin | Tuberculinum; Tuberculin; Tuberculinum crudum; Old tuberculin | 12CH | Solution from the concentrated soluble products of growth of the tubercle bacillus (Mycobacterium tuberculosis) |
| Tuberculinum bovinum; Bovine tuberculin | Tuberculinum bovinum; Bovine tuberculin | 12CH | Solution from the concentrated soluble products of growth of the bovine tubercle bacillus (Mycobacterium bovis) |
| Vaccinotoxinum; Smallpox | Vaccinotoxinum; Smallpox; Vaccininum; Variolae fluidum | 12CH | Living virus of vaccinia from strain of approved origin and grown on skin of vaccinated bovine calf |
| Variolinum | Variolinum | 12CH | Lymph from small-pox pustule |