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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.



April 29, 2022

Proper name(s), Common name(s), Source information

Table 1. Proper name(s), Common name(s), Source information
Proper name(s) Common name(s)
Source information
Source material(s) Part(s) Preparation(s)

Juglans nigra

Black walnut

Juglans nigra

Unripe hull


References: Proper name: USDA 2018; Common name: USDA 2018; Source information: Mills and Bone 2005, Tilgner 1999.

Route of Administration


Dosage Form(s)

This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.

Acceptable dosage forms for oral use are indicated in the dosage form drop-down list of the web-based Product Licence Application form for Compendial applications.

Use(s) or Purpose(s)

(Traditionally) used in Herbal Medicine (as a vermifuge/as an anthelmintic) to help expel intestinal worms (Mills and Bone 2005; Willard 1991; Grieve 1971).


Claims for traditional use must include the term "Herbal Medicine", "Traditional Chinese Medicine", or "Ayurveda".



Adults 18 years and older


Methods of preparation: Dry, Powder, Non-Standardised Ethanolic Extracts (Dry extract, Tincture, Fluid extract)

0.65 - 2.75 grams of unripe hulls, per day (Mills and Bone 2005; Willard 1991).

Direction(s) for use

No statement required.

Duration(s) of Use

Risk Information

Caution(s) and warning(s)


No statement required.

Known adverse reaction(s)

No statement required.

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredients Database (NHPID) and must meet the limitations outlined in the database.

Storage conditions

Must be established in accordance with the requirements described in the Natural Health Products Regulations (NHPR).


References Cited

References Reviewed