GLOBE ARTICHOKE - CYNARA CARDUNCULUS

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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.

Notes

Date

December 18, 2018

Proper name(s), Common name(s), Source material(s)

Table 1. Proper name(s), Common name(s), Source material(s)
Proper name(s) Common name(s) Source material(s)
Proper name(s) Part(s) Preparation

Cynara cardunculus

  • Artichoke
  • Artichoke thistle
  • Cardoon
  • Cynara
  • Garden artichoke
  • Globe artichoke
  • Scotch thistle

Cynara cardunculus

Leaf

Dried

References: Proper name: USDA 2018; Common names: McGuffin et al. 2000; Source material: Bradley 2006, ESCOP 2003, Blumenthal et al. 2000.

Route of Administration

Oral

Dosage Form(s)

This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.

Acceptable dosage forms for the age category listed in this monograph and specified route of administration are indicated in the Compendium of Monographs Guidance Document.

Use(s) or Purpose(s)

The following combined use(s) or purpose(s) is/are also acceptable:

Used in Herbal Medicine to help relieve digestive upset, such as indigestion and help increase bile flow (choleretic) (Bradley 2006; Mills and Bone 2005; ESCOP 2003; Hoffmann 2003; Blumenthal et al. 2000).

Dose(s)

Subpopulation(s)

Adults 18 years and older

Quantity(ies)

Methods of preparation: Dry, Powder, Non-Standardised Extracts (Dry extract, Tincture, Fluid extract, Decoction, Infusion)

1.5 - 10 grams of dried leaf, per day (Bradley 2006; Mills and Bone 2005; ESCOP 2003; Blumenthal et al. 2000).

Direction(s) for use

No statement required.

Duration(s) of Use

No statement required.

Risk Information

Caution(s) and warning(s)

Contraindication(s)

Do not use this product if you have a bile duct obstruction (Brinker 2010; Bradley 2006; ESCOP 2003; Blumenthal et al. 2000).

Known adverse reaction(s)

Stop use if hypersensitivity/allergy occurs (Brinker 2010; Bradley 2006; ESCOP 2003; Blumenthal et al. 2000).

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredients Database (NHPID) and must meet the limitations outlined in the database.

Storage conditions

No statement required.

Specifications

References Cited

References Reviewed