Monograph: Rosemary - Oral

Date: 2018-12-18

NHPID name

Rosmarinus officinalis ( Germplasm Resources Information Network Taxonomy )

Proper name(s)

Rosmarinus officinalis L. (Lamiaceae) ( USDA 2008 )

Common name(s)

Rosemary ( McGuffin et al. 2000 )

Source material

Leaf ( Blumenthal et al. 2000 )

Route Of administration

Oral ( ESCOP 2003 )

Dosage form(s)

Those suited to the allowable route(s) of administration. This monograph is not intended to include food-like dosage forms such as bars, chewing gums or beverages.

Use(s) or purpose(s)

Statement(s) to the effect of:

• (Traditionally) used in Herbal Medicine to help ease (gastric) headaches and relieve flatulent indigestion (carminative).
• (Traditionally) used in Herbal Medicine to help relieve flatulent indigestion (carminative).  (Barnes et al. 2007, Bradley 2006, Mills and Bone 2005, ESCOP 2003, Hoffmann 2003, Blumenthal et al. 2000)
• (Traditionally) used in Herbal Medicine to help ease (gastric) headaches.  (Barnes et al. 2007, Bradley 2006, Mills and Bone 2005, Hoffmann 2003, Blumenthal et al. 2000, Tilgner 1999, Grieve 1971[1931])

Dose(s)

Adults:

See Appendix 1 for examples of appropriate dosage preparations and frequencies of use, according to cited references. The purpose of Appendix 1 is to provide guidance to industry.

Duration of use

No statement is required

Risk information

Statement(s) to the effect of:

Caution(s) and Warning(s): Consult a health care practitioner/health care provider/health care professional/doctor/physician if symptoms persist or worsen.  (Barnes et al. 2007, Brinker 2001, Blumenthal et al. 2000, McGuffin et al. 1997) Contraindication(s): Do not use this product if you are pregnant or breastfeeding. Known Adverse Reaction(s): No statement is required

Non-medicinal ingredients

Must be chosen from the current Natural health products ingredients database and must meet the limitations outlined in the database.

Specifications

• The finished product specifications must be established in accordance with the requirements described in the NHPD Quality of natural health products guide.
• The medicinal ingredient must comply with the requirements outlined in the Natural health products ingredient database (NHPID).

References cited

• Barnes J, Anderson LA, Philipson JD. 2007. Herbal Medicines, 3rd edition. London (GB): Pharmaceutical Press.
• BHP 1983: British Herbal Pharmacopoeia. Cowling (GB): British Herbal Medical Association; 1983.
• Blumenthal M, Goldberg A, Brinckmann J, editors. Herbal Medicine: Expanded Commission E Monographs. Boston (MA): Integrative Medicine Communications; 2000.
• Bradley PR, editor. British Herbal Compendium: A Handbook of Scientific Information on Widely Used Plant Drugs, Volume 2. Bournemouth (UK): British Herbal Medicine Association; 2006.
• Brinker F. 2001. Herb Contraindications and Drug Interactions, 3rd edition. Sandy (OR): Eclectic Medical Publications.
• ESCOP 2003: ESCOP Monographs: The Scientific Foundation for Herbal Medicinal Products, 2nd edition. Exeter (UK): European Scientific Cooperative on Phytotherapy and Thieme; 2003.
• Grieve M. 1971. A Modern Herbal, Volume 1. New York (NY): Dover Publications [Reprint of 1931 Harcourt, Brace & Company publication].
• Hoffmann D. 2003. Medical Herbalism: The Science and Practice of Herbal Medicine. Rochester (VT): Healing Arts Press.
• McGuffin M, Hobbs C, Upton R, Goldberg A, editors. 1997. American Herbal Products Association's Botanical Safety Handbook. Boca Raton (FL): CRC Press.
• McGuffin M, Kartesz JT, Leung AY, Tucker AO, editors. 2000. Herbs of Commerce, 2nd edition. Austin(TX): American Herbal Products Association.
• Mills S, Bone K. 2005. The Essential Guide to Herbal Safety. St. Louis (MO): Elsevier Churchill Livingstone.
• Tilgner S. Herbal Medicine from the Heart of the Earth. Creswell (OR): Wise Acre Press; 1999.
• USDA 2008: ARS, National Genetic Resources Program. Germplasm Resources Information Network (GRIN). National Germplasm Resources Laboratory, Beltsville (MD). [Accessed 2008-01-21]. Available at http://www.ars-grin.gov/cgi-bin/npgs/html/tax_search.pl
• Wichtl M, editor. Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis, 3rd edition. Stuttgart (D): Medpharm GmbH Scientific Publishers; 2004.
• Williamson EM, Evans FJ, Wren RC. Potter's New Cyclopaedia of Botanical Drugs and Preparations. Saffron Walden (GB): C.W. Daniel Company Limited; 1988.

Appendix 1: Examples of appropriate dosage preparations, frequencies of use and directions for use

ORAL:

Dried leaf:

• 4 - 6 g, per day (Barnes et al. 2007)
• 6 - 12 g, per day (Mills and Bone 2005)
• 4 - 6 g, per day (Blumenthal et al. 2000)
• 2 - 4 g, 3 times per day (BHP 1983)

Infusion:

• 6 - 12 g dried leaf, per day (Mills and Bone 2005)
• 2 - 4 g dried leaf, per day (ESCOP 2003)
• 2 g dried leaf, 3 times per day (Blumenthal et al. 2000)
• 2 - 4 g dried leaf, 3 times per day (BHP 1983)

Directions for use:

Pour 150 ml of boiling water on dried leaf and infuse (Blumenthal et al. 2000).

Fluid extract:

• 6 - 12 g dried equivalent, per day (1:1, 6-12 ml) (Mills and Bone 2005)
• 1.5 - 3 g dried equivalent, per day (1:1, 45% ethanol, 1.5-3 ml) (ESCOP 2003)
• 2 g dried equivalent, 3 times per day (1:1, 2 ml) (Blumenthal et al. 2000)
• 2 - 4 g dried equivalent, 3 times per day (1:1, 45% alcohol, 2-4 ml) (BHP 1983)

Tincture:

• 0.6 - 1.7 g dried equivalent, per day (1:5, 70% ethanol, 3-8.5 ml) (ESCOP 2003)
• 0.2 - 0.4 g dried equivalent, 3 times per day (1:5, 40% ethanol, 1-2 ml) (Hoffmann 2003)
• 2 g dried equivalent, 3 times per day (1:5, 10 ml) (Blumenthal et al. 2000)