Monograph: Chamomile, Roman

Date: 2018-10-30

NHPID name

Chamaemelum nobile ( Germplasm Resources Information Network Taxonomy )

Proper name(s)

Chamaemelum nobile ( USDA 2008 )

Common name(s)

• Garden chamomile ( Unavailable )
• Noble chamomile ( Unavailable )
• Roman chamomile ( USDA 2008 , McGuffin et al. 2000 )
• Russian chamomile ( Unavailable )

Source material

Flower ( Wichtl 2004 , Bradley 1992 )

Route Of administration

Oral

Dosage form(s)

• The acceptable pharmaceutical dosage forms include, but are not limited to capsules, chewables (e.g. gummies, tablets), liquids, powders, strips or tablets.
• This monograph is not intended to include foods or food-like dosage forms such as bars, chewing gums or beverages.

Use(s) or purpose(s)

Statement(s) to the effect of:

(Traditionally) used in Herbal Medicine to help relieve mild digestive disturbances (such as dyspepsia, nausea, flatulence).  (Wichtl 2004, Mills and Bone 2000, Bradley 1992, BHP 1983, Ellingwood 1983[1919], Felter 1983[1922])

Dose(s)

Adults:

See Appendix 1 for examples of appropriate dosage preparations and frequencies of use, according to cited references. The purpose of Appendix 1 is to provide guidance to industry.

Duration of use

No statement is required

Risk information

Statement(s) to the effect of:

Caution(s) and Warning(s): Consult a health care practitioner/health care provider/health care professional/doctor/physician if symptoms persist or worsen. Contraindication(s): No statement is required Known Adverse Reaction(s): Stop use if hypersensitivity/allergy occurs.  (Brinker 2001, Mills and Bone 2000, Blumenthal et al. 1998)

Non-medicinal ingredients

Must be chosen from the current Natural health products ingredients database and must meet the limitations outlined in the database.

Specifications

• The finished product specifications must be established in accordance with the requirements described in the NHPD Quality of natural health products guide.
• The medicinal ingredient must comply with the requirements outlined in the Natural health products ingredient database (NHPID).
• The medicinal ingredient may comply with the specifications outlined in the 'Chamomile Flowers' monograph of the British Pharmacopoeia or the 'Chamomile Flower, Roman' monograph of the European Pharmacopoeia.

References cited

• BHP 1983: British Herbal Pharmacopoeia. Cowling (GB): British Herbal Medical Association; 1983.
• Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Riggins C, Rister R, editors. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin (TX): American Botanical Council; 1998.
• BP 2008: British Pharmacopoeia, Volume 1. Londron (UK): British Pharmacopoeia Commission. The Stationary Office.
• Bradley PR, editor. 1992. British Herbal Compendium: A Handbook of Scientific Information on Widely Used Plant Drugs, Volume 1. Bournemouth (GB): British Herbal Medicine Association.
• Brinker F. 2001. Herb Contraindications and Drug Interactions, 3rd edition. Sandy (OR): Eclectic Medical Publications.
• Ellingwood F. 1983. American Materia Medica, Therapeutics and Pharmacognosy. Sandy (OR): Eclectic Medical Publications [Reprint of 1919 original].
• European Pharmacopoeia, 6th edition. Strasbourg (France): Directorate for the Quality of Medicines and HealthCare of the Council of Europe (EDQM).; 2008
• Felter HW. The Eclectic Materia Medica, Pharmacology and Therapeutics. Sandy (OR): Eclectic Medical Publications; 1983 [Reprint of 1922 original].
• McGuffin M, Hobbs C, Upton R, Goldberg A, editors. 1997. American Herbal Products Association's Botanical Safety Handbook. Boca Raton (FL): CRC Press.
• McGuffin M, Kartesz JT, Leung AY, Tucker AO, editors. 2000. Herbs of Commerce, 2nd edition. Austin(TX): American Herbal Products Association.
• Mills S, Bone K. 2000. Principles and Practice of Phytotherapy. Toronto (ON): Churchill Livingstone.
• USDA 2008: ARS, National Genetic Resources Program. Germplasm Resources Information Network (GRIN). National Germplasm Resources Laboratory, Beltsville (MD). [Accessed 2008-01-21]. Available at http://www.ars-grin.gov/cgi-bin/npgs/html/tax_search.pl
• Wichtl M, editor. Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis, 3rd edition. Stuttgart (D): Medpharm GmbH Scientific Publishers; 2004.

References reviewed

• Barnes J, Anderson LA, Philipson JD. 2007. Herbal Medicines, 3rd edition. London (GB): Pharmaceutical Press.
• Brinker F. 2010. Online Updates and Additions to Herb Contraindications and Drug Interactions, 3rd edition. Sandy (OR): Eclectic Medical Publications. [Updated 2010 July 13; Accessed 2013 January 30]. Available from: http://www.eclecticherb.com/emp/updatesHCDI.html
• Carnat A, Carnat AP, Fraisse D, Ricoux L, Lamaison JL. 2004. The aromatic and polyphenolic composition of Roman camomile tea. Fitoterapia 75(1):32-38
• Mills S, Bone K. 2005. The Essential Guide to Herbal Safety. St. Louis (MO): Elsevier Churchill Livingstone.

Appendix 1: Examples of appropriate dosage preparations, frequencies of use and directions for use

Dried flower:

• 1.5-3g, 3 times per day (Bradley 1992)
• 1-4g, 3 times per day (BHP 1983)

Infusion:

• 2-3g dried flower (Wichtl 2004)
• 1.5-3g dried flower, three times daily (Bradley 1992)
• Directions for use: Pour boiling water over the finely cut dried flower. Steep for 10 min and then strain (Wichtl 2004).

Fluid extract:

• 1.5-3g dried equivalent, 3 times per day (1:1, 70% ethanol, 1.5-3 ml) (Bradley 1992)
• 1-4g dried equivalent, three times per day (1:1, 70% ethanol, 1-4 ml) (BHP 1983)

Tincture:

0.6-1g dried equivalent, three times per day (1:5, 1-5 ml) (Bradley 1992)