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Drugs and Health Products

Monograph: Ground Ivy - Oral

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Date: 2008-03-05


Glechoma hederacea (USDA 2008)

Proper Name(s)

Glechoma hederacea L. (Lamiaceae) ( USDA 2008 )

Common Name(s)

Ground ivy ( McGuffin et al. 2000 )

Source Material

Herb top ( Barnes et al. 2007 , Grieve 1971[1931] )

Route Of Administration


Dosage Form(s)

Those suited to the allowable route(s) of administration. This monograph is not intended to include food-like dosage forms such as bars, chewing gums or beverages.

Use(s) or Purpose(s)

Statement(s) to the effect of:



Preparation: Dry, Powder, Decoction & Infusion + All Non-Standardised Extracts

Dose(s): 2 - 12 Grams per day, dried herb tops

See Appendix 1 for examples of appropriate dosage preparations and frequencies of use, according to cited references. The purpose of Appendix 1 is to provide guidance to industry.

Duration of use

Diuretic: For occasional use only  (Berardi et al. 2002, CPA 2002)

Risk Information

Statement(s) to the effect of:

Caution(s) and Warning(s):
  • Consult a health care practitioner if symptoms persist.
  • Consult a health care practitioner if symptoms worsen.
  • Consult a health care practitioner prior to use if you are pregnant or breastfeeding  (Barnes et al. 2007)

No statement is required

Known Adverse Reaction(s):
No statement is required

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredients Database and must meet the limitations outlined in the database.


  • The finished product specifications must be established in accordance with the requirements described in the NHPD Quality of Natural Health Products Guide.
  • The medicinal ingredient must comply with the requirements outlined in the Natural Health Products Ingredient Database (NHPID).

References cited

  • Barnes J, Anderson LA, Philipson JD. 2007. Herbal Medicines, 3rd edition. London (GB): Pharmaceutical Press.
  • Bartram T. Bartram's Encyclopedia of Herbal Medicine: The Definitive Guide to the Herbal Treatments of Diseases. New York (NY): Marlowe & Company; 1998.
  • Berardi RR, DeSimone EM, Newton GD, Oszko MA, Popovich NG, Rollins CJ, Shimp LA, Tietze KJ, editors. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 13th edition. Washington (DC): American Pharmaceutical Association; 2002.
  • Bradley PR, editor. 1992. British Herbal Compendium: A Handbook of Scientific Information on Widely Used Plant Drugs, Volume 1. Bournemouth (GB): British Herbal Medicine Association.
  • CPA 2002: Canadian Pharmacists Association. Patient Self-Care. Helping Patients Make Therapeutic Choices. Ottawa (ON): Canadian Pharmacists Association; 2002.
  • Grieve M. 1971. A Modern Herbal, Volume 1. New York (NY): Dover Publications [Reprint of 1931 Harcourt, Brace & Company publication].
  • McGuffin M, Kartesz JT, Leung AY, Tucker AO, editors. 2000. Herbs of Commerce, 2nd edition. Austin(TX): American Herbal Products Association.
  • USDA 2008: ARS, National Genetic Resources Program. Germplasm Resources Information Network (GRIN). National Germplasm Resources Laboratory, Beltsville (MD). [Accessed 2008-01-21]. Available at
  • Williamson EM, Evans FJ, Wren RC. Potter's New Cyclopaedia of Botanical Drugs and Preparations. Saffron Walden (GB): C.W. Daniel Company Limited; 1988.

References reviewed

  • BHP 1996: British Herbal Pharmacopoeia. Bournemouth (UK): British Herbal Medical Association; 1996.
  • Brinker F. 2001. Herb Contraindications and Drug Interactions, 3rd edition. Sandy (OR): Eclectic Medical Publications.
  • Cook, WH. The Physio-medical Dispensatory. Cincinnati (OH): WH Cook; 1869. [Accessed 2008-02-14]. Available from:
  • Felter HW, Lloyd JU. 1983. King's American Dispensatory, Volume 2, 18th edition. Sandy (OR): Eclectic Medical Publications [Reprint of 1898 original].
  • Gruenwald J, Brendler T, Jaenicke C, editors. PDR for Herbal Medicines, 2nd edition. Montvale (NJ): Medical Economics Co.; 1998.
  • Hoffmann D. The Complete Illustrated Holistic Herbal. Rockport (MA): Element Books Inc.; 1996.
  • Lontos S, Jones RM, Angus PW, Gow PJ. Acute liver failure associated with the use of herbal preparations containing black cohosh. The Medical journal of Australia 2003;179(7):390-1.
  • Moerman DE . 1998. Native American Ethnobotany. Portland (OR): Timber Press.
  • Remington JP and Woods HC, editors. The Dispensatory of the United States of America, 20th edition. 1918. [Accessed 2008-02-14]. Available from:
  • Sayre LE. A Manuel of Organic Materia Medica and Pharmacognosy, 4th edition. Philadelphia (PA): P. Blakiston's Son & Co; 1917. [Accessed 2008-02-14]. Available from:
  • Thomsen M, Vitetta L, Sali A, Schmidt M. Acute liver failure associated with the use of herbal preparations containing black cohosh. The Medical journal of Australia 2004; 180(11):598-9.
  • Wiersema J, León B. 1999. World Economic Plants: A Standard Reference. Boca Raton (FL): CRC Press LLC.

Appendix 1: Examples of appropriate dosage preparations, frequencies of use and directions for use


Dried aerial parts:

2 - 4 g, 3 times per day (Bradley 1992)


2 - 4 g dried aerial parts, 3 times per day (Bradley 1992)

Fluid extract:

  • 2 - 4 g dried equivalent, 3 times per day (1:1; 25% ethanol, 2-4 ml) (Bradley 1992)
  • 2 - 4 g dried equivalent per day (1:1, 2-4 ml) (Williamson et al. 1988; Grieve 1971 [1931])


1 - 2 g dried equivalent, 3 times a day (1:5, 25% ethanol, 5-10 ml) (Bradley 1992)