Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on May 13, 2022.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Lemongrass Oil

Role:
Non-medicinal


NHPID Name:
Rhododendron Ferrugineum Extract

Role:
Non-medicinal


NHPID Name:
Miliacin

Role:
Component


NHPID Name:
Tasmannia Lanceolata Fruit/Leaf Extract

Role:
Non-medicinal


NHPID Name:
Lycium Barbarum Seed Oil

Role:
Non-medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

NHPID Name:
Magnesium bisglycinate

Role:
No role


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:
Cymbopogon Flexuosus Oil

New NHPID Name:
Cymbopogon Flexuosus Oil


Old NHPID Name:
Leucine hydrochloride

New NHPID Name:
L-Leucine hydrochloride


Old NHPID Name:
N-Acetylleucine

New NHPID Name:
N-Acetyl-L-leucine


Old NHPID Name:
Lysine acetate

New NHPID Name:
L-Lysine acetate


Old NHPID Name:
Lysine dihydrochloride

New NHPID Name:
L-Lysine dihydrochloride


Old NHPID Name:
Tryptophan

New NHPID Name:
L-Tryptophan


Old NHPID Name:
1,5,5,9-Tetramethyl-13-oxatricyclo[8.3.0.0.(4.9)]tridecane

New NHPID Name:
Amberlyn


Old NHPID Name:
Caffeoylquinic acids

New NHPID Name:
Caffeoylquinic acids


Old NHPID Name:
Neohesperidin dihydrochalcone

New NHPID Name:
Neohesperidin Dihydrochalcone


NHPID Name:
Cymbopogon Flexuosus Oil

Removed Common Name(s):
Cymbopogon Flexuosus Essential Oil


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Cymbopogon Flexuosus Oil

New Common Name(s):
Cymbopogon flexuosus oil


NHPID Name:
L-Histidine hydrochloride

Removed Common Name(s):
L-Histidine monohydrochloride


NHPID Name:
L-Histidine hydrochloride

New Common Name(s):
L-Histidine monohydrochloride


NHPID Name:
L-Lysine-L-aspartate

New Common Name(s):
L-Lysine-L-aspartate


NHPID Name:
L-Lysine monohydrochloride

Removed Proper Name(s):
(S)-2,6-Diaminohexanoic monohydrochloride


NHPID Name:
L-Lysine monohydrochloride

New Proper Name(s):
L-Lysine monohydrochloride


NHPID Name:
L-Lysine acetate

Removed Proper Name(s):
L-2,6-Diaminohexanoic acid acetate


NHPID Name:
L-Lysine acetate

New Proper Name(s):
L-2,6-Diaminohexanoic acid acetate


NHPID Name:
L-Lysine dihydrochloride

New Common Name(s):
L-Lysine dihydrochloride


NHPID Name:
Ginkgo Biloba Leaf Extract

Removed Common Name(s):
Ginkgo Extract; Maidenhair Extract; Ginkgo Biloba


NHPID Name:
Amberlyn

New Common Name(s):
Amberlyn


NHPID Name:
Amberlyn

Removed Common Name(s):
1,5,5,9-Tetramethyl-13-oxatricyclo[8.3.0.0.(4.9)]tridecane


NHPID Name:
Caffeoylquinic acids

New Common Name(s):
Caffeoylquinic acids


NHPID Name:
Caffeoylquinic acids

New Proper Name(s):
Caffeoylquinic acids


NHPID Name:
Caffeoylquinic acids

Removed Common Name(s):
Caffeoylquinic acids


NHPID Name:
Caffeoylquinic acids

Removed Proper Name(s):
Caffeoylquinic acids


NHPID Name:
Neohesperidin Dihydrochalcone

Removed Common Name(s):
Neohesperidin dihydrochalcone


NHPID Name:
Neohesperidin Dihydrochalcone

New Common Name(s):
Neohesperidin dihydrochalcone


NHPID Name:
East Indian Lemongrass Essential Oil

Old Role:
Medicinal & Non-medicinal


NHPID Name:
N-Acetyl-L-leucine

Old Role:
Medicinal


NHPID Name:
N-Glycyl-L-leucine

Old Role:
Medicinal


NHPID Name:
L-Lysine acetate

Old Role:
Medicinal


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
N-Acetyl-L-methionine

Old Role:
Medicinal

New Role:
No role


NHPID Name:
DL-Phenylalanine

Old Role:
Medicinal

New Role:
No role


NHPID Name:
Cymbopogon Flexuosus Oil

New Non-medicinal Restriction(s) added:
For topical use only, up to 0.7%.



NHPID Name:
Cymbopogon Flexuosus Oil

Restriction Reference removed:
CosIng



NHPID Name:
Cymbopogon Flexuosus Oil

New Restriction Reference added:
EQSAFTY2



NHPID Name:
Durapatite

Non-medicinal Restriction(s) removed:
For topical use only.



Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Durapatite

New Non-medicinal Restriction(s) added:
General


NHPID Name:
L-Histidine

New Non-medicinal Restriction(s) added:
Up to 0.05%.


NHPID Name:
L-Histidine

Restriction Reference removed:
ICID


NHPID Name:
L-Histidine

New Restriction Reference added:
CIR


NHPID Name:
L-Histidine hydrochloride

New Non-medicinal Restriction(s) added:
For topical use only, up to 0.07%.


NHPID Name:
L-Histidine hydrochloride

Restriction Reference removed:
ICID


NHPID Name:
L-Histidine hydrochloride

New Restriction Reference added:
CIR


NHPID Name:
L-Isoleucine

New Route(s) of Adminstration added:
Oral


NHPID Name:
L-Isoleucine

Restriction Reference removed:
UNAVA


NHPID Name:
L-Isoleucine

New Restriction Reference added:
WHO_JECFA


NHPID Name:
L-Isoleucine

New Non-medicinal Restriction(s) added:
General


NHPID Name:
L-Leucine

New Route(s) of Adminstration added:
Oral


NHPID Name:
L-Leucine

Restriction Reference removed:
UNAVA


NHPID Name:
L-Leucine

New Restriction Reference added:
HPE_2009


NHPID Name:
L-Leucine

New Non-medicinal Restriction(s) added:
General


NHPID Name:
L-Lysine

New Restriction Reference added:
Oral


NHPID Name:
L-Lysine

New Non-medicinal Restriction(s) added:
General; General


NHPID Name:
L-Lysine

Restriction Reference removed:
UNAVA


NHPID Name:
L-Lysine

New Restriction Reference added:
Appl_Micro_Biot_92(609)


NHPID Name:
L-Lysine monohydrochloride

New Non-medicinal Restriction(s) added:
Up to 0.6%.


NHPID Name:
L-Lysine monohydrochloride

Restriction Reference removed:
ICID


NHPID Name:
L-Lysine monohydrochloride

New Restriction Reference added:
CIR


NHPID Name:
L-Methionine

New Route(s) of Adminstration added:
Oral


NHPID Name:
L-Methionine

Restriction Reference removed:
UNAVA


NHPID Name:
L-Methionine

New Restriction Reference added:
HPE_2009


NHPID Name:
L-Phenylalanine

New Route(s) of Adminstration added:
Oral


NHPID Name:
L-Phenylalanine

Restriction Reference removed:
UNAVA


NHPID Name:
L-Phenylalanine

New Restriction Reference added:
FHFI_2010


NHPID Name:
L-Phenylalanine

New Non-medicinal Restriction(s) added:
General


NHPID Name:
L-Threonine

New Route(s) of Adminstration added:
Oral


NHPID Name:
L-Threonine

Restriction Reference removed:
UNAVA


NHPID Name:
L-Threonine

New Restriction Reference added:
NNHPD


NHPID Name:
L-Threonine

New Non-medicinal Restriction(s) added:
General


NHPID Name:
DL-Threonine

New Route(s) of Adminstration added:
Oral


NHPID Name:
DL-Threonine

Restriction Reference removed:
UNAVA


NHPID Name:
DL-Threonine

New Restriction Reference added:
Appl_Micro_Biot_92(609)


NHPID Name:
L-Tryptophan

New Route(s) of Adminstration added:
Oral


NHPID Name:
L-Tryptophan

New Non-medicinal Restriction(s) added:
General


NHPID Name:
L-Tryptophan

Restriction Reference removed:
HCSF; UNAVA


NHPID Name:
L-Tryptophan

New Restriction Reference added:
PDL; EUR_J_PH_BIOPH


NHPID Name:
L-Valine

New Route(s) of Adminstration added:
Oral


NHPID Name:
L-Valine

New Non-medicinal Restriction(s) added:
General


NHPID Name:
L-Valine

Restriction Reference removed:
UNAVA


NHPID Name:
L-Valine

New Restriction Reference added:
NNHPD


NHPID Name:
Ginkgo Biloba Leaf Extract

New Non-medicinal Restriction(s) added:
For topical use only, up to 0.25%, when formulated to be non-sensitizing.


NHPID Name:
Ginkgo Biloba Leaf Extract

Restriction Reference removed:
ICID


NHPID Name:
Ginkgo Biloba Leaf Extract

New Restriction Reference added:
CIR


NHPID Name:
Amberlyn

New Non-medicinal Restriction(s) added:
For oral use only.


NHPID Name:
Amberlyn

Restriction Reference removed:
JECFA


NHPID Name:
Amberlyn

New Restriction Reference added:
WHO_JECFA


NHPID Name:
Phellodendron Amurense Bark Extract

New Non-medicinal Restriction(s) added:
For topical use only.


NHPID Name:
Neohesperidin Dihydrochalcone

New Non-medicinal Restriction(s) added:
For buccal or oral use only.


NHPID Name:
Neohesperidin Dihydrochalcone

Restriction Reference removed:
UNAVA


NHPID Name:
Neohesperidin Dihydrochalcone

New Restriction Reference added:
HPE_2009


NHPID Name:
Cymbopogon Flexuosus Oil

Modification:
Removed Schedule 1: Extract


NHPID Name:
Cymbopogon Flexuosus Oil

Method(s) of Preparation removed:
Oil, Essential (water steam distillation) Standardized


NHPID Name:
Cymbopogon Flexuosus Oil

Removed NMI purpose(s):
Masking Agent


NHPID Name:
Cymbopogon Flexuosus Oil

New NMI Purpose(s):
Fragrance Ingredient


NHPID Name:
L-Leucine

Removed NMI purpose(s):
Fragrance Ingredient


NHPID Name:
L-Leucine hydrochloride

Name Reference removed:
MI; NNHPD; MI; NNHPD


NHPID Name:
L-Leucine hydrochloride

New Name Reference added:
CHEMID; CHEMID; CHEMID; CHEMID


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
N-Acetyl-L-leucine

Name Reference removed:
DNP


NHPID Name:
N-Acetyl-L-leucine

New Name Reference added:
CHEMID


NHPID Name:
N-Acetyl-L-leucine

Modification:
Removed Schedule 1: Isolate


NHPID Name:
N-Glycyl-L-leucine

Modification:
Removed Schedule 1:Isolate


NHPID Name:
L-Lysine monohydrochloride

Name Reference removed:
MI; MI


NHPID Name:
L-Lysine monohydrochloride

New Name Reference added:
CHEMID; CHEMID


NHPID Name:
L-Lysine acetate

Modification:
Removed Schedule 1:Isolate


NHPID Name:
L-Lysine acetate

Name Reference removed:
USP_31; MARO


NHPID Name:
L-Lysine acetate

New Name Reference added:
PUBCHEM; CHEMID


NHPID Name:
L-Lysine dihydrochloride

Name Reference removed:
EPA; EPA


NHPID Name:
L-Lysine dihydrochloride

New Name Reference added:
CHEMID; CHEMID


NHPID Name:
L-Methionine

New Name Reference added:
MIO; MIO; MIO


NHPID Name:
L-Methionine

Name Reference removed:
NMCD; NMCD; NMCD


NHPID Name:
N-Acetyl-L-methionine

Modification:
Removed Schedule 1:Isolate


NHPID Name:
Calcium

New Source Material(s) added:
Hyriopsis cumingii (Parts: Pearl)


NHPID Name:
Hyriopsis cumingii

New Sub-ingredient(s) added:
Calcium


NHPID Name:
Hyriopsis cumingii

Modification:
New Source Material Constituent(s): Pearl


NHPID Name:
Panicum miliaceum

Modification:
New Source Material Constituent(s): Seed


NHPID Name:
Panicum miliaceum

New Sub-ingredient(s) added:
Miliacin


NHPID Name:
Ginkgo Biloba Leaf Extract

Modification:
Removed Schedule 1:Extract


NHPID Name:
Ginkgo Biloba Leaf Extract

Method(s) of Preparation removed:
Extract liquid standardized; Extract dry standardized


NHPID Name:
Amberlyn

New Name Reference added:
CHEMID; WHO_JECFA


NHPID Name:
Amberlyn

Name Reference removed:
EC-FL; EC-FL


NHPID Name:
Phellodendron Amurense Bark Extract

Modification:
Removed Schedule 1: Plant and plant material


NHPID Name:
Phellodendron Amurense Bark Extract

Source Material(s) removed:
Phellodendron amurense ( Parts: Stem bark )


NHPID Name:
Phellodendron Amurense Bark Extract

New Source Material(s) added:
Phellodendron amurense ( Parts: Bark )


NHPID Name:
Phellodendron Amurense Bark Extract

Method(s) of Preparation removed:
Dry; Extract dry standardized; Extract liquid standardized; Powdered


NHPID Name:
Caffeoylquinic acids

Modification:
Revised Category: Herbal Component Name


NHPID Name:
Caffeoylquinic acids

New Source Material(s) added:
Cynara cardunculus ( Parts: Flower bud )


NHPID Name:
Cynara cardunculus

Name Reference removed:
UNAVA


NHPID Name:
Cynara cardunculus

New Name Reference added:
GRIN


NHPID Name:
Cynara cardunculus

New Sub-ingredient(s) added:
Caffeoylquinic acids


NHPID Name:
Cynara cardunculus

Modification:
Source Material Constituent(s): Flower bud


NHPID Name:
Eugenol

New Source Material(s) added:
Ocimum tenuiflorum ( Parts: Leaf )


NHPID Name:
Ocimum tenuiflorum

Modification:
New Source Material Constituent(s):Leaf


NHPID Name:
Ocimum tenuiflorum

New Sub-ingredient(s) added:
Eugenol


NHPID Name:
Bombyx mori

Method(s) of Preparation removed:
Live


NHPID Name:
Bombyx mori

New Method(s) of Preparation added:
Dry , Fresh


NHPID Name:
Bombyx mori

New Name Reference added:
ITIS


NHPID Name:
Bombyx mori

Name Reference removed:
UNAVA


NHPID Name:
Neohesperidin Dihydrochalcone

New Toxicity restriction added:
Acceptable daily intake up to 5 mg/kg bw/day.


Old NHPID Name:
Magnesium glycinate

New NHPID Name:
Magnesium bisglycinate


NHPID Name:
Magnesium bisglycinate

Removed Proper Name(s):
Magnesium diglycinate


NHPID Name:
Magnesium bisglycinate

Removed Common Name(s):
Magnesium bisglycinate


NHPID Name:
Magnesium bisglycinate

New Common Name(s):
Magnesium bisglycinate


NHPID Name:
Magnesium bisglycinate

New Sub-ingredient(s) added:
Glycine


NHPID Name:
Magnesium bisglycinate

Route(s) of Adminstration removed:
Oral


NHPID Name:
Magnesium bisglycinate

Restriction Reference removed:
CHEMID


NHPID Name:
Magnesium bisglycinate

New Restriction Reference added:
EFSA


NHPID Name:
Magnesium bisglycinate

Name Reference removed:
CHEMID


NHPID Name:
Magnesium bisglycinate

New Name Reference added:
EFSA


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.

RemIng

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