Health Canada
Symbol of the Government of Canada
Drugs and Health Products

Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on October 24, 2017.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Opuntia Ficus-Indica Seed Oil

Role:
Non-medicinal


NHPID Name:
Primula elatior

Role:
Medicinal


NHPID Name:
C24-28 Alkyldimethylsiloxy Trimethylsiloxysilicate

Role:
Non-medicinal


NHPID Name:
Alumina hydrate

Role:
Non-medicinal


NHPID Name:
Prunus salicina 'Queen Garnet'

Role:
Medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

NHPID Name:
Pantethine octahydrate

Role:
Medicinal


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

No Changes.


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Cetearyl Ethylhexanoate

Removed Proper Name(s):
Cetearyl Ethylhexanoate


NHPID Name:
Cetearyl Ethylhexanoate

New Proper Name(s):
2-Ethylhexanoic acid, cetyl/stearyl ester


NHPID Name:
Cetyl Ethylhexanoate

Removed Common Name(s):
Cetyl 2-ethylhexanoate


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
Dicreatine malate

Old Role:
Medicinal

New Role:
No role


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
C12-15 Alkyl Ethylhexanoate

New Route(s) of Adminstration added:
Topical


NHPID Name:
C12-15 Alkyl Ethylhexanoate

New Non-medicinal Restriction(s) added:
For topical use only, up to 22%, when formulated to be non-irritating.


NHPID Name:
Cetearyl Ethylhexanoate

New Non-medicinal Restriction(s) added:
For topical use only, up to 35%, when formulated to be non-irritating.


NHPID Name:
Cetyl Ethylhexanoate

New Non-medicinal Restriction(s) added:
For topical use only, up to 77% in rinse-off products and up to 52% in leave-on products, when formulated to be non-irritating.


NHPID Name:
Tridecyl Ethylhexanoate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Tridecyl Ethylhexanoate

New Non-medicinal Restriction(s) added:
For topical use only, when formulated to be non-irritating.


NHPID Name:
Potassium hydroxide

Route(s) of Adminstration removed:
Topical


NHPID Name:
Potassium hydroxide

Route(s) of Adminstration removed:
Oral


NHPID Name:
Potassium hydroxide

New Non-medicinal Restriction(s) added:
For topical use only for the purpose of viscosity increasing agent - aqueous, up to 10% in rinse-off products and up to 7% in leave-on products, when formulated to be non-irritating.


NHPID Name:
Phosphorus pentoxide

Route(s) of Adminstration removed:
Dental


NHPID Name:
Phosphorus pentoxide

Route(s) of Adminstration removed:
Topical


NHPID Name:
Hydrogen peroxide

New Non-medicinal Restriction(s) added:
For buccal, dental, or topical use only, if not contributing to the product's claim(s), and not recommended for children under 12 years of age. The pH of products to be applied to the tooth or teeth must be greater than or equal to 4.0. If a buccal or dental product contains more than 3% hydrogen peroxide, the product must not cause the saliva or soft tissue of the oral cavity to exceed 3% hydrogen peroxide. Duration of use: For prolonged use, consult a health care practitioner. Risk statement: Avoid swallowing the product, and avoid contact with eyes. Risk statement for buccal or dental products: If irritation (such as redness, swelling, soreness) of the gums or the mouth occurs, discontinue use and consult a health care practitioner.


NHPID Name:
Hydrogen peroxide

New Restriction Reference added:
CIH


NHPID Name:
Hydrogen peroxide

Route(s) of Adminstration removed:
Topical


NHPID Name:
Hydrogen peroxide

Route(s) of Adminstration removed:
Dental


NHPID Name:
Methyl salicylate

Non-medicinal Restriction(s) changed:
Up to a maximum concentration of 1% in buccal, dental, and topical products.


NHPID Name:
Copper phthalocyanine

New Route(s) of Adminstration added:
Dental


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Creatine

New Source Ingredient(s) added:
Creatine hydrochloride


NHPID Name:
Creatine

New Source Ingredient(s) added:
Creatine monohydrate


NHPID Name:
Creatine

New Source Ingredient(s) added:
Dicreatine malate


NHPID Name:
Phosphoric acid

New Toxicity restriction added:
Group maximum tolerable daily intake of up to 70 mg/kg bw/day for phosphorus from all sources, expressed as P.


NHPID Name:
Sodium bisulfite

New Toxicity restriction added:
Group acceptable daily intake of up to 0.7 mg/kg bw/day, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide.


NHPID Name:
Hydrogen peroxide

Additional Details changed:
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in topical natural health products, unless additional evidence for safety is submitted. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php.


NHPID Name:
Anthocyanins

New Source Material(s) added:
Prunus salicina 'Queen Garnet'


NHPID Name:
Methyl salicylate

Additional Details changed:
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potential safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included as non-medicinal ingredient in natural health products, unless additional evidence for safety is submitted. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php.


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.


PREVIOUS WHAT'S NEW