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Drugs and Health Products

Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on May 05, 2017.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Ethylhexyl Cocoate

Role:
Non-medicinal


NHPID Name:
Glyceryl Glucoside

Role:
Non-medicinal


NHPID Name:
Rubus Coreanus Fruit Extract

Role:
Non-medicinal


NHPID Name:
Prunus Domestica Seed Oil

Role:
Non-medicinal


NHPID Name:
Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate

Role:
Non-medicinal


NHPID Name:
Sanicula Europaea Extract

Role:
Non-medicinal


NHPID Name:
Polyglyceryl-6 Pentaoleate

Role:
Non-medicinal


NHPID Name:
Olive oil polyglyceryl-6 esters

Role:
Non-medicinal


NHPID Name:
Mother of Pearl

Role:
Non-medicinal


NHPID Name:
Lilium Candidum Bulb Extract

Role:
Non-medicinal


NHPID Name:
Prunus Mume Flower Extract

Role:
Non-medicinal


NHPID Name:
Pinus Sylvestris Leaf Extract

Role:
Non-medicinal


NHPID Name:
Benzophenone-1

Role:
Non-medicinal


NHPID Name:
Potassium Olivoyl PCA

Role:
Non-medicinal


NHPID Name:
Gelidium Sesquipedale Extract

Role:
Non-medicinal


NHPID Name:
PEG-22/Dodecyl Glycol Copolymer

Role:
Non-medicinal


NHPID Name:
Methoxy PEG-22/Dodecyl Glycol Copolymer

Role:
Non-medicinal


NHPID Name:
Radix et Rhizoma Piperis Laetispici

Role:
Medicinal


NHPID Name:
Eucalyptus Staigeriana Branch/Leaf Oil

Role:
Non-medicinal


NHPID Name:
Dimethyl Lauramine

Role:
Non-medicinal


NHPID Name:
Bacillus subtilis DE111

Role:
Medicinal


NHPID Name:
Orange Oil Coldpressed

Role:
Non-medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

No Changes.


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:
DL-Menthone 1,2-glycerol ketal

New NHPID Name:
Menthone glycerin acetal


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
L-Arginine monohydrochloride

New Common Name(s):
Arginine HCl


NHPID Name:
Menthone glycerin acetal

New Proper Name(s):
DL-Menthone 1,2-glycerol ketal


NHPID Name:
Menthone glycerin acetal

Removed Common Name(s):
DL-Menthone 1,2-glycerol ketal


NHPID Name:
Menthone glycerin acetal

New Common Name(s):
Menthone glycerin acetal


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
L-Arginine monohydrochloride

Old Role:
No role

New Role:
Non-medicinal


NHPID Name:
Rice bran oil

Old Role:
No role

New Role:
Medicinal


NHPID Name:
D-Glucose monohydrate

Old Role:
Medicinal

New Role:
Non-medicinal


NHPID Name:
Ibogaine hydrochloride

Old Role:
Medicinal

New Role:
No role


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Juniperus Oxycedrus Wood Essential Oil

New Non-medicinal Restriction(s) added:
For topical use only. Only rectified (purified) oils may be used. The finished product may not contain more than 1 ppb of polycyclic aromatic hydrocarbons (PAHs).


NHPID Name:
Juniperus Oxycedrus Wood Essential Oil

Restriction Reference removed:
ICID


NHPID Name:
Juniperus Oxycedrus Wood Essential Oil

New Restriction Reference added:
EQSAFTY2


NHPID Name:
Litsea Cubeba Fruit Oil

New Non-medicinal Restriction(s) added:
For topical use only.


NHPID Name:
Octisalate

New Non-medicinal Restriction(s) added:
When it is not associated with a health claim, Octisalate is an acceptable non-medicinal ingredient in a natural health product in the minimum concentration necessary to achieve the excipient effect. If this ingredient contributes to the recommended use, the product is a drug, not an NHP.


NHPID Name:
Octinoxate

New Non-medicinal Restriction(s) added:
When it is not associated with a health claim, octinoxate is an acceptable non-medicinal ingredient in a natural health product in the minimum concentration necessary to achieve the excipient effect. If this ingredient contributes to the recommended use, the product is a drug, not an NHP.


NHPID Name:
Benzalkonium chloride

Method(s) of Preparation removed:
For topical use only. Maximum concentration permitted 0.1% for use as a preservative antimicrobial (i.e. benzalkonium chloride with chain lengths below or equal to 14 C). Maximum concentration permitted 3% in rinse-off hair care products (i.e. benzalkonium chloride with chain length equal or above 16 C). Risk statement " Avoid contact with eyes " required for all products containing more than 0.1% benzalkonium chloride.


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Polyphosphorylcholine Glycol Acrylate

New NMI Purpose(s):
Skin-Conditioning Agent


NHPID Name:
Citrus bergamia

New Sub-ingredient(s) added:
Polyphenols


NHPID Name:
Fish Oil

Modification:
Family: Gadidae


NHPID Name:
Vitis vinifera

New Sub-ingredient(s) added:
Polyphenols


NHPID Name:
Vitis vinifera

New Sub-ingredient(s) added:
Resveratrol


NHPID Name:
Oryza sativa

New Sub-ingredient(s) added:
Tocotrienol concentrate


NHPID Name:
Choline bitartrate

New Additional Details added :
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. This ingredient cannot be used in topical natural health products without the submission of additional evidence for safety. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php.


NHPID Name:
Menthone glycerin acetal

New NMI Purpose(s):
Fragrance Ingredient


NHPID Name:
Vitis rotundifolia

New Source Ingredient(s) added:
Fruit skin


NHPID Name:
Litsea Cubeba Fruit Oil

New NMI Purpose(s):
Flavour Enhancer - Natural


NHPID Name:
Euterpe oleracea

New Non-medicinal Restriction(s) added:
Anthocyanins


NHPID Name:
Herba Senecionis Scandentis

New Toxicity restriction added:
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Herba Senecionis Scandentis.


NHPID Name:
Aspergillus niger

New Sub-ingredient(s) added:
Glucosamine hydrochloride


NHPID Name:
Orange Oil Distilled

Method(s) of Preparation removed:
Oil, Essential (enfleurage)


NHPID Name:
Orange Oil Distilled

Method(s) of Preparation removed:
Oil, Essential (enfleurage) Standardised


NHPID Name:
Orange Oil Distilled

Method(s) of Preparation removed:
Oil, Essential (expression)


NHPID Name:
Orange Oil Distilled

Method(s) of Preparation removed:
Oil, Essential (expression) Standardised


NHPID Name:
Orange Oil Distilled

Method(s) of Preparation removed:
Oil, Essential (other methods of preparation)


NHPID Name:
Orange Oil Distilled

Method(s) of Preparation removed:
Oil, Essential (other methods of preparation) Standardised


NHPID Name:
Benzalkonium chloride

Method(s) of Preparation removed:
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included as a non-medicinal ingredient in natural health products, unless additional evidence for safety is submitted. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php.


NHPID Name:
Ibogaine hydrochloride

New Sub-ingredient(s) added:
Ibogaine


NHPID Name:
EHP_Oleander

New Additional Details added :
The minimum acceptable homeopathic potency is set at 6X, due to safety concerns identified with herbal material from the Nerium oleander plant.


NHPID Name:
HAB_Nerium oleander

New Additional Details added :
The minimum acceptable homeopathic potency is set at 6X, due to safety concerns identified with herbal material from the Nerium oleander plant.


NHPID Name:
HPUS_Oleander

New Additional Details added :
The minimum acceptable homeopathic potency is set at 6X, due to safety concerns identified with herbal material from the Nerium oleander plant.


NHPID Name:
PhF_Nerium oleander

New Additional Details added :
The minimum acceptable homeopathic potency is set at 6X, due to safety concerns identified with herbal material from the Nerium oleander plant.


NHPID Name:
Tridecyl Trimellitate

New CAS Registry Number(s) added:
94109-09-8


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.


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