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Drugs and Health Products

Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on December 13, 2016.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Garcinia Indica Seed Butter

Role:
Non-medicinal


NHPID Name:
Crocin

Role:
No role


NHPID Name:
Caprooyl Sphingosine

Role:
Non-medicinal


NHPID Name:
Caprooyl Phytosphingosine

Role:
Non-medicinal


NHPID Name:
Ceramide EOS

Role:
Non-medicinal


NHPID Name:
Citrus Aurantium Amara (Bitter Orange) Flower Extract

Role:
Non-medicinal


NHPID Name:
Hymenolepis diminuta

Role:
Medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

No Changes.


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

No Changes.


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Phenacetin

Removed Common Name(s):
p-acetophenetide


NHPID Name:
Phenacetin

New Common Name(s):
Phenacetin


NHPID Name:
EHP_Phenacetinum and HPUS_Phenacetinum

Removed Proper Name(s):
Phenacetin


NHPID Name:
EHP_Phenacetinum and HPUS_Phenacetinum

New Proper Name(s):
Acetic acid N (4-ethoxyphenyl-amide)-p-Acetophenetidide


NHPID Name:
EHP_Phenacetinum and HPUS_Phenacetinum

Removed Common Name(s):
Acetic acid N (4-ethoxyphenyl-amide)-p-Acetophenetidide


NHPID Name:
L-Methionine

New Proper Name(s):
(S)-2-Amino-4-(methylthio)butanoic acid


NHPID Name:
Saccharin sodium dihydrate

New Common Name(s):
Saccharin sodium; Sodium saccharin


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
Nitrate

Old Role:
Non-medicinal

New Role:
Medicinal


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Dioctyl Adipate

Non-medicinal Restriction(s) changed:
For topical use only. Maximum of 6.0% in topical leave-on products, except in products intended for local application only (e.g. less than 10% of body surface area).


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Spinacia oleracea

New Sub-ingredient(s) added:
Protein


NHPID Name:
Citrate

New Source Material(s) added:
Sodium citrate and Potassium citrate


NHPID Name:
Crocus sativus

New Sub-ingredient(s) added:
Crocin


NHPID Name:
Geraniol

New Toxicity restriction added:
Maximum concentration permitted 5.3%. For topical use on intact skin only.


NHPID Name:
Melia Azadirachta Seed Oil

New Toxicity restriction added:
For topical use on intact skin only. Maximum concentration permitted 1%.


NHPID Name:
Formaldehyde

Additional Details changed:
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in topical natural health products, unless additional evidence for safety is submitted. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php


NHPID Name:
Formaldehyde

New Toxicity restriction added:
Not permitted in aerosol products. Up to 0.01% in non-aerosol products that release formaldehyde vapors when used according to directions. Up to 0.1% in oral and buccal products. Up to 0.2% as a preservative in topical products, except for products used on nails only. Up to 5.0% in topical nail product.


NHPID Name:
Dioctyl Adipate

Additional Details changed:
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in topical natural health products, unless additional evidence for safety is submitted. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php


NHPID Name:
Butane

New Additional Details added :
The presence of this ingredient on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. This ingredient must be used in accordance with the restrictions set out on the Hotlist when included in topical natural health products, unless additional evidence for safety is submitted. Reference: http://www.hc-sc.gc.ca/cps-spc/cosmet-person/hot-list-critique/hotlist-liste-eng.php


NHPID Name:
Dioscorea oppositifolia

New Taxonomical Synonym(s) added:
Dioscorea opposita Thunb (not the same name as Dioscorea opposita auct.)


NHPID Name:
Dioscorea oppositifolia

Taxonomical Synonym(s) removed:
Dioscorea opposita


NHPID Name:
Saccharomyces cerevisiae

New Sub-ingredient(s) added:
beta-1,3/1,6-Glucan


NHPID Name:
Symphytum Officinale Root Extract

New Toxicity restriction added:
Testing must be performed to ensure that the amount of pyrrolizidine alkaloids does not exceed 0.35 micrograms per day. For topical use on intact skin only. For short-term use, in adults only.


NHPID Name:
Madagascan Ho leaf essential oil (Cineol CT)

Medicinal Rationale changed:
Classified as an NHP under Schedule 1 item 2 (an extract) of the Natural Health Products Regulations. The volatile oil of the plant Cinnamomum camphorum (cineole chemotype) is sometimes called Ravintsara Essential Oil. This name is not to be confused with the volatile oil of a different species, Cryptocarya agathophylla, or Aromatic Ravensare, which is sometimes called Ravensara Essential Oil.


NHPID Name:
Ravensara Aromatica Leaf Oil

Additional Details changed:
The volatile oil of the plant Cryptocarya agathophylla, or Aromatic Ravensare, is sometimes called Ravensara Essential Oil. This name is not to be confused with the volatile oil of a different species, Cinnamomum camphorum (cineole chemotype), which is sometimes called Ravintsara Essential Oil.


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

Modification:
Test method "AOAC 2002.05-2002, Quantity of Cholecalciferol (vitamin D3) in selected products" added


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.


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