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Drugs and Health Products

Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on July 12, 2016.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Hyptis Suaveolens Seed Oil

Role:
Non-medicinal


NHPID Name:
Copaifera Reticulata Balsam Oil

Role:
Non-medicinal


NHPID Name:
Lonicera Japonica Callus Extract

Role:
Non-medicinal


NHPID Name:
Iris Pallida Leaf Cell Extract

Role:
Non-medicinal


NHPID Name:
Hydrolyzed Hibiscus esculentus Extract

Role:
Non-medicinal


NHPID Name:
Semen Celosiae

Role:
Medicinal


NHPID Name:
Flos Jasmini

Role:
Medicinal


NHPID Name:
Petiolus Trachycarpi

Role:
Medicinal


NHPID Name:
Radix Boehmeriae

Role:
Medicinal


NHPID Name:
Berberis Aquifolium Extract

Role:
Non-medicinal


NHPID Name:
Salacia chinensis

Role:
Medicinal


NHPID Name:
Dimethicone/Vinyltrimethylsiloxysilicate Crosspolymer

Role:
Non-medicinal


NHPID Name:
Satureja Montana Oil

Role:
Non-medicinal


NHPID Name:
Hyssopus Officinalis Leaf Oil

Role:
Non-medicinal


NHPID Name:
Radix Mahoniae

Role:
Medicinal


NHPID Name:
Pterocarpus Santalinus Wood Extract

Role:
Non-medicinal


NHPID Name:
Ocotea Quixos Leaf Oil

Role:
Non-medicinal


NHPID Name:
Flos Genkwa

Role:
Medicinal


NHPID Name:
Nelumbo Nucifera Flower Wax

Role:
Non-medicinal


NHPID Name:
Haematite

Role:
Medicinal


NHPID Name:
Caffeoylquinic acids

Role:
No role


NHPID Name:
Cynaropicrin

Role:
No role


NHPID Name:
Total gingerols and shogaols

Role:
No role


NHPID Name:
Coutareagenin

Role:
No role


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

NHPID Name:
Micronised Purified Flavonoid Fraction

Role:
Medicinal


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:
1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, potassium salt

New NHPID Name:
Saccharin potassium


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Saccharin

Removed Common Name(s):
o-Sulfobenzimide


NHPID Name:
Saccharin potassium

Removed Common Name(s):
Saccharin, potassium salt


NHPID Name:
Saccharin potassium

New Common Name(s):
Potassium saccharin


NHPID Name:
Saccharin potassium

New Common Name(s):
Saccharin potassium


NHPID Name:
Picea mariana Leaf Oil

Removed Common Name(s):
Picea mariana Leaf Oil


NHPID Name:
Picea mariana Leaf Oil

New Common Name(s):
Picea mariana leaf essential oil


NHPID Name:
Stevia rebaudiana leaf

New Common Name(s):
Stevia leaf


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

NHPID Name:
Chlorhexidine

Old Role:
Non-NHP

New Role:
Non-medicinal & Non-NHP


NHPID Name:
Capsaicin

Old Role:
Medicinal

New Role:
Medicinal & Non-medicinal


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Diethylene glycol

New Non-medicinal Restriction(s) added:
For topical use only. Not permitted on leave-on products.


NHPID Name:
Triethylene glycol

New Non-medicinal Restriction(s) added:
For topical use only.


NHPID Name:
Butoxydiglycol

New Non-medicinal Restriction(s) added:
For topical use only.


NHPID Name:
Chlorhexidine acetate

New Restriction Reference added:
CIH


NHPID Name:
Chlorhexidine acetate

Restriction Reference removed:
CIR


NHPID Name:
Chlorhexidine acetate

New Non-medicinal Restriction(s) added:
Up to 0.19% calculated as chlorhexidine diacetate; Up to 0.14% calculated as chlorhexidine free base (Route Of Administration: Topical)


NHPID Name:
Chlorhexidine acetate

New Non-medicinal Restriction(s) added:
Up to 0.01% w/v calculated as chlorhexidine free base (Route Of Administration: Ophthalmic)


NHPID Name:
Chlorhexidine gluconate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Chlorhexidine gluconate

New Restriction Reference added:
CIH


NHPID Name:
Chlorhexidine gluconate

Non-medicinal Restriction(s) changed:
Up to 0.20% calculated as chlorhexidine digluconate; Up to 0.14% calculated as chlorhexidine free base (Route Of Administration: Topical)


NHPID Name:
Chlorhexidine gluconate

New Non-medicinal Restriction(s) added:
Ophthalmic


NHPID Name:
Chlorhexidine gluconate

New Restriction Reference added:
KIBBEO


NHPID Name:
Chlorhexidine gluconate

New Non-medicinal Restriction(s) added:
Up to 0.01% w/v calculated as chlorhexidine free base (Route Of Administration: Ophthalmic)


NHPID Name:
Saccharin Sodium

New Route(s) of Adminstration added:
Oral


NHPID Name:
Calcium saccharin

New Route(s) of Adminstration added:
Oral


NHPID Name:
Saccharin sodium dihydrate

Route(s) of Adminstration removed:
Buccal, Topical


NHPID Name:
Saccharin sodium dihydrate

New Route(s) of Adminstration added:
Oral


NHPID Name:
Methenamine

New Route(s) of Adminstration added:
Topical


NHPID Name:
Cinnamomum Zeylanicum Leaf Oil

New Route(s) of Adminstration added:
Oral


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Indian Frankincense Boswellic acids-Phosphatidylcholine complex

New Sub-ingredient(s) added:
Boswellic acids (Part: Gum oleoresin)


NHPID Name:
Chlorhexidine

Non-NHP Rationale changed:
A non-NHP because not a naturally occurring substance included in Schedule 1 of the Natural Health Products Regulations. Chlorhexidine and its salts are listed on the Prescription Drug List as follows: Chlorhexidine or its salts, when used as a topical oral preparation.


NHPID Name:
Chlorhexidine acetate

Non-NHP Rationale changed:
A non-NHP because not a naturally occurring substance included in Schedule 1 of the Natural Health Products Regulations. Chlorhexidine and its salts are listed on the Prescription Drug List as follows: Chlorhexidine or its salts, when used as a topical oral preparation.


NHPID Name:
Chlorhexidine gluconate

Non-NHP Rationale changed:
A non-NHP because not a naturally occurring substance included in Schedule 1 of the Natural Health Products Regulations. Chlorhexidine and its salts are listed on the Prescription Drug List as follows: Chlorhexidine or its salts, when used as a topical oral preparation.


NHPID Name:
Saccharin

Additional Details changed:
Acceptable daily intake up to 5 mg/kg b.w./day for saccharin and its calcium, potassium and sodium salts, singly or in combination. It is also expected that saccharin present in a natural health product be of food / pharmaceutical grade (e.g. FCC / USP).


NHPID Name:
Saccharin Sodium

Additional Details changed:
Acceptable daily intake up to 5 mg/kg b.w./day for saccharin and its calcium, potassium and sodium salts, singly or in combination. It is also expected that saccharin sodium present in a natural health product be of food / pharmaceutical grade (e.g. FCC / USP).


NHPID Name:
Calcium saccharin

New Additional Details added :
Acceptable daily intake up to 5 mg/kg b.w./day for saccharin and its calcium, potassium and sodium salts, singly or in combination. It is also expected that saccharin calcium present in a natural health product be of food / pharmaceutical grade (e.g. FCC / USP).


NHPID Name:
Saccharin potassium

Additional Details changed:
Acceptable daily intake up to 5 mg/kg b.w./day for saccharin and its calcium, potassium and sodium salts, singly or in combination. It is also expected that saccharin potassium present in a natural health product be of food / pharmaceutical grade (e.g. FCC / USP)


NHPID Name:
Saccharin sodium dihydrate

New Additional Details added :
Acceptable daily intake up to 5 mg/kg b.w./day for saccharin and its calcium, potassium and sodium salts, singly or in combination. It is also expected that saccharin sodium dihydrate present in a natural health product be of food / pharmaceutical grade (e.g. FCC / USP).


NHPID Name:
Synephrine

New Source Material(s) added:
Citrus aurantium - fruit


NHPID Name:
Picea mariana Leaf Oil

Method(s) of Preparation removed:
Extract dry, Extract dry standardised, Extract liquid, Extract liquid standardised


NHPID Name:
Picea mariana Leaf Oil

New Method(s) of Preparation added:
Oil, Essential (water steam distillation)


NHPID Name:
Picea mariana Leaf Oil

New NMI Purpose(s):
Masking Agent


NHPID Name:
Cinnamomum Zeylanicum Leaf Oil

New NMI Purpose(s):
Flavour Enhancer - Natural


NHPID Name:
Cynara cardunculus - Leaf

New Sub-ingredient(s) added:
Bioflavonoids, Caffeoylquinic acids, Cynaropicrin


NHPID Name:
Zingiber officinale - Root

New Sub-ingredient(s) added:
Total gingerols and shogaols


NHPID Name:
Serrapeptase

New Source Material(s) added:
Serratia marcescens E-15


NHPID Name:
Citrus bioflavonoids

New Sub-ingredient(s) added:
Diosmin


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.


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