Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on June 11, 2013.
- Announcements
- New Ingredients
- Removed Ingredients
- Revised NHPID Names
- Revised Proper and Common Names
- New Roles
- Revised Restrictions
- Other Ingredient Modifications
- Monograph Modifications
- AbLS Modifications
- Controlled Vocabulary Modifications
- Homeopathic Ingredient Modifications
- Previous What's New
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent versions of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest versions of the e-PLA, namely versions 1.4.4 and 2.2.0. Version 1.4.4, known as the Cfgm ePLA, is dedicated to applications of type Compendial from generated monographs (Cfgm), which are used when attesting to a generated single ingredient monograph. Version 2.2.0 is for all application types except for Compendial from generated monographs. The forms are available for downloading from http://www.hc-sc.gc.ca/dhp-mps/prodnatur/applications/online-enligne/guidance-reference-eng.php.
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
PVM/MA Decadiene Crosspolymer
Role:
Non-medicinal
NHPID Name:
L-Carnitine fumarate
Role:
Medicinal & Non-NHP
NHPID Name:
Glycyrrhiza Inflata Root Extract
Role:
Non-medicinal
NHPID Name:
Ulva Lactuca Powder
Role:
Non-medicinal
NHPID Name:
Vilanterol
Role:
Non-NHP
NHPID Name:
Olodaterol
Role:
Non-NHP
NHPID Name:
Pertuzumab
Role:
Non-NHP
NHPID Name:
Brentuximab vedotin
Role:
Non-NHP
NHPID Name:
Regorafenib
Role:
Non-NHP
NHPID Name:
Ulipristal Acetate
Role:
Non-NHP
NHPID Name:
Madecassoside
Role:
Non-medicinal
NHPID Name:
Mango juice
Role:
Non-medicinal
NHPID Name:
Apricot Juice
Role:
Non-medicinal
NHPID Name:
Spinacia oleracea (Spinach) extract
Role:
Non-medicinal
NHPID Name:
Parthenium integrifolium
Role:
Medicinal
NHPID Name:
Concentrated ammonia solution
Role:
Non-medicinal
NHPID Name:
Carbomer homopolymer
Role:
Non-medicinal
NHPID Name:
Acetogenins
Role:
No role
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
No Changes.
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
N-stearoyl-DL--sphinganine
New NHPID Name:
N-stearoyl-DL-erythro-sphinganine
Old NHPID Name:
Origanum minutiflorum herb oil
New NHPID Name:
Origanum minutiflorum herb essential oil
Old NHPID Name:
Oryzin
New NHPID Name:
Aspergillus alkaline protease
Old NHPID Name:
Foeniculum vulgare. subsp. vulgare var. dulce
New NHPID Name:
Foeniculum vulgare subsp. vulgare var. dulce
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
D&C Red No. 28
New Common Name(s):
C.I. 45410
NHPID Name:
Lithol Rubin B
New Common Name(s):
C.I. 15850
NHPID Name:
Citral
Removed Proper Name(s):
Citral
NHPID Name:
Citral
Removed Common Name(s):
2,6-Octadienal, 3,7-dimethyl-; 3,7-Dimethyl-2,6-octadienal; 3,7-dimethylocta-2,6-dienal; 3,7-Dimethyl-trans-2,6-octadienal
NHPID Name:
Citral
New Proper Name(s):
3,7-Dimethyl-2,6-octadienal
NHPID Name:
Citral
New Common Name(s):
Citral
NHPID Name:
Citronellyl acetate
Removed Proper Name(s):
Citronellyl acetate
NHPID Name:
Citronellyl acetate
Removed Common Name(s):
(1)-3,7-Dimethyloct-6-enyl acetate; 3,7-Dimethyl-6-octen-1-ol acetate; 3,7-Dimethyl-6-octen-1-yl Acetate; 3,7-Dimethyl-6-octen-1-yl ethanoate; 3,7-dimethyloct-6-enyl acetate; 6-Octen-1-ol, 3,7-dimethyl-, acetate; 6-Octen-l-ol, 3,7-dimethyl-, acetate; Acetic acid, citronellyl ester
NHPID Name:
Citronellyl acetate
New Proper Name(s):
(1)-3,7-Dimethyloct-6-enyl acetate; 6-Octen-1-ol, 3,7-dimethyl-, acetate
NHPID Name:
Citronellyl acetate
New Common Name(s):
Citronellyl acetate
NHPID Name:
Epimedium sagittatum
New Common Name(s):
Sagittate epimedium
NHPID Name:
Fungal protease
New Common Name(s):
Aspergillus acid protease
NHPID Name:
Senegalia catechu
New Common Name(s):
Acacia catechu
NHPID Name:
Honey
Removed Common Name(s):
Feng mi
NHPID Name:
Leptospermum scoparium Honey
New Proper Name(s):
Leptospermum scoparium Honey
NHPID Name:
Leptospermum scoparium Honey
Removed Common Name(s):
Apis mellifera
NHPID Name:
Foeniculum vulgare subsp. vulgare var. dulce
New Proper Name(s):
Foeniculum vulgare subsp. vulgare var. dulce
NHPID Name:
Foeniculum vulgare subsp. vulgare var. dulce
Removed Common Name(s):
Foeniculum vulgare subsp. vulgare var. dulce
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
NHPID Name:
L-Lactic acid
Old Role:
Non-medicinal
New Role:
Medicinal & Non-medicinal
NHPID Name:
Choline bitartrate
Old Role:
Medicinal
New Role:
Medicinal & Non-medicinal
NHPID Name:
alpha-Linolenic acid
Old Role:
Medicinal
New Role:
Medicinal & Non-medicinal
NHPID Name:
Wheatgrass
Old Role:
Non-medicinal
New Role:
Medicinal & Non-medicinal
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Sage Essential Oil Dalmation
Restriction Reference removed:
FCC
NHPID Name:
Sage Essential Oil Dalmation
Non-medicinal Restriction(s) removed:
Flavour Enhancer
NHPID Name:
Honey
New Route(s) of Adminstration added:
Route Of Administration: Oral
NHPID Name:
Honey
New Route(s) of Adminstration added:
Route Of Administration: Topical
NHPID Name:
Acorus calamus
New Medicinal Restriction(s) added :
Toxic limits for beta-asarone: No more than (NMT) 10 mg/kg beta-asarone in dried rhizome of Acorus gramineus or NMT 115 mcg/day of beta-asarone in finished products.
NHPID Name:
Arthrospira maxima
New Medicinal Restriction(s) added :
As Spirulina species contain predominantly pseudo-vitamin B12, potencies of vitamin B12 are only acceptable if the supporting assays are based on the amount of bioactive, rather than bioavailable, vitamin B12.
NHPID Name:
Arthrospira platensis
Medicinal Restriction(s) Changed :
As Spirulina species contain predominantly pseudo-vitamin B12, potencies of vitamin B12 are only acceptable if the supporting assays are based on the amount of bioactive, rather than bioavailable, vitamin B12.
NHPID Name:
Borago officinalis
New Medicinal Restriction(s) added :
Leaves, stems and extracts of Borago officinalis must be tested to ensure absence of unsaturated pyrrolizidine alkaloids.
NHPID Name:
Equisetum arvense
New Medicinal Restriction(s) added :
Testing must be performed to ensure absence of thiaminase-like activity in Equisetum arvense.
NHPID Name:
Eupatorium perfoliatum
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Eupatorium purpureum.
NHPID Name:
Hydrangea arborescens
New Medicinal Restriction(s) added :
Testing must be performed to ensure absence of cyanogenic glycosides in Hydrangea arborescens.
NHPID Name:
Origanum minutiflorum
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Origanum majorana
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Origanum onites
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Origanum syriacum
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Origanum vulgare
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Origanum vulgare subsp hirtum
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Origanum vulgare subsp vulgare
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Thymus serpyllum
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Thymus vulgaris
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
Petasites hybridus
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Petasites hybridus
NHPID Name:
Piper methysticum
New Medicinal Restriction(s) added :
The amount of kavalactones in Piper methysticum should be provided for the Safety and Efficacy assessment of Product Licence Applications.
NHPID Name:
Senecio scandens
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Senecio scandens.
NHPID Name:
Symphytum officinale
Medicinal Restriction(s) removed:
Safety issues raised by the Canadian Poisonous Plant Information System need to be taken into consideration.
NHPID Name:
Symphytum officinale
Medicinal Restriction(s) removed:
Testing must be performed to ensure the absence of pyrrolizidine alkaloids (e.g. Echimidine) in Symphytum officinale
NHPID Name:
Tussilago farfara
New Medicinal Restriction(s) added :
Testing must be performed to ensure the absence of pyrrolizidine alkaloids in Tussilago farfara
NHPID Name:
Viscum album
New Medicinal Restriction(s) added :
Testing must be performed on Viscum album to ensure a maximum level of viscotoxin in the finished product of 17 µg/mL (or µg/g
NHPID Name:
Glycerol
Route(s) of Adminstration removed:
Rectal
NHPID Name:
Glycerol
New Route(s) of Adminstration added:
Oral
NHPID Name:
Shark cartilage
New Medicinal Restriction(s) added :
Testing must be performed to ensure absence of beta-N-Methylamino-L-alanine (BMAA) in shark cartilage.
NHPID Name:
Origanum majorana leaf oil;
Oleoresin Marjoram Sweet; Origanum vulgare leaf extract;
Origanum vulgare leaf oil;
Sweet marjoram essential oil;
Thymus Vulgaris (Thyme) Leaf Extract; Origanum minutiflorum herb essential oil
New Non-medicinal Restriction(s) added:
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
NHPID Name:
European Oregano Essential Oil; Greek Oregano Essential Oil; Oleoresin Marjoram Sweet; Oregano Oil; Origanum Oil Spanish; Sweet marjoram essential oil; Turkish Oregano Essential Oil
New Medicinal Restriction(s) added :
The quantity or concentration of carvacrol in all applicable essential oils or extracts must be declared.
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
PEG-6 Caprylic/Capric Glycerides
New NMI Purpose(s):
Emulsifying Agent; Surfactant
NHPID Name:
Ammonio methacrylate copolymer dispersion
New Additional Details added :
Ammonio methacrylate copolymer dispersion is an aqueous dispersion of Ammonio methacrylate copolymer Type A or B in water (USP).
NHPID Name:
Sage Essential Oil Dalmation
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Sage Essential Oil Dalmation
Additional Details removed:
Flavouring agent only
NHPID Name:
Vilanterol
New Source Ingredient(s) added:
Vilanterol trifenatate
NHPID Name:
Olodaterol
New Source Ingredient(s) added:
Olodaterol hydrochloride
NHPID Name:
Terpineol
New NMI Purpose(s):
Fragrance Ingredient
NHPID Name:
Carboxypolymethylene
New CAS Registry Number(s) added:
9003-01-04
NHPID Name:
Bioflavonoids
New Source Material(s) added:
Scutellaria baicalensis
NHPID Name:
Bioflavonoids
New Source Material(s) added:
Senegalia catechu
NHPID Name:
(+)-Catechin
New Source Material(s) added:
Senegalia catechu
NHPID Name:
Sodium bicarbonate
New Additional Details added :
Sodium is an electrolyte, not a nutrient. As a medicinal ingredient sodium does not contribute to the maintenance of good health since there is likely to be excess sodium from the diet, not a deficiency. The safety and efficacy of the sodium bicarbonate as a source of sodium must be assessed under the recommended conditions of use.
NHPID Name:
Wheatgrass
New Method(s) of Preparation added:
Fresh
NHPID Name:
alpha-Hydroxyisocaproic acid
New Source Ingredient(s) added:
alpha-Hydroxyisocaproic acid
NHPID Name:
Glycyrrhiza glabra (Root)
New Sub-ingredient(s) added:
Licochalcone A
NHPID Name:
Glycyrrhiza inflata (Root)
New Sub-ingredient(s) added:
Licochalcone A
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
Modification:
Posting for consultaion of:
- Chitosan
- Phaseolus vulgaris (Kidney bean)
- L-carnitine
- Oat beta glucan
- Inulin
- Cayenne
Modification:
Final posting of the folllowing monographs: melatonin- Oral and sublingual
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
No Changes.
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.