Natural Health Products Ingredients Database
WHAT'S NEW
What's New is a listing of modifications to the NHPID since the
last update. This page was most recently revised on July 17, 2012.
ANNOUNCEMENTS
The updates to the NHPID listed below apply to the most recent versions of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest versions of the e-PLA, namely versions 1.4.4 and 2.0.1. Version 1.4.4, known as the Cfgm ePLA, is dedicated to applications of type Compendial from generated monographs (Cfgm), which are used when attesting to a generated single ingredient monograph. Version 2.0.1 is for all application types except for Compendial from generated monographs. The forms are available for downloading from http://www.hc-sc.gc.ca/dhp-mps/prodnatur/applications/online-enligne/guidance-reference-eng.php.
New Ingredients
In this update, the following non-homeopathic ingredients were added.
NHPID Name:
Ceramide 1
Role:
Non-medicinal
NHPID Name:
Stachys Officinalis Flower/Leaf/Stem Extract
Role:
Non-medicinal
NHPID Name:
Soy Isoflavones
Role:
Non-medicinal
NHPID Name:
Acetyl glucosamine
Role:
Non-medicinal
NHPID Name:
Ethylbisiminomethylguaiacol Manganese Chloride
Role:
Non-medicinal
NHPID Name:
Ferula gummosa gum resin
Role:
Non-medicinal
NHPID Name:
Yolk protein
Role:
Medicinal
NHPID Name:
Mimosa tenuiflora leaf extract
Role:
Non-medicinal
NHPID Name:
Safflower Oil/Palm Oil Aminopropanediol Esters
Role:
Non-medicinal
NHPID Name:
Fragaria virginiana fruit
Role:
Non-medicinal
NHPID Name:
Zinc citrate trihydrate
Role:
Medicinal
NHPID Name:
Saponaria officinalis
Role:
Medicinal
NHPID Name:
Cordyceps
Role:
Medicinal
NHPID Name:
Mandarin orange fruit
Role:
Non-medicinal
NHPID Name:
Coprinus comatus
Role:
Medicinal
NHPID Name:
Coconut Alkanes
Role:
Non-medicinal
NHPID Name:
Placental protein
Role:
Non-medicinal
NHPID Name:
PPG-9 Diglyceryl Ether
Role:
Non-medicinal
NHPID Name:
Sodium Carbonate Peroxide
Role:
Non-medicinal
Removed Ingredients
In this update, the following non-homeopathic ingredients were removed.
NHPID Name:
Mastic, Storax, Molasses, Gum Benzoin
Role:
Medicinal
NHPID Name:
Lime Oil Distilled, Lime Oil Coldpressed
Role:
Non-medicinal
NHPID Name:
Mace Oil, East Indian
Role:
Medicinal & Non-medicinal
NHPID Name:
Mace Oil, West Indian
Role:
Medicinal & Non-medicinal
Revised NHPID Names
In this update, the following non-homeopathic ingredients had their NHPID name revised.
Old NHPID Name:
Linaloe Wood Oil
New NHPID Name:
Linaloe Wood Essential Oil
Old NHPID Name:
Lovage Oil
New NHPID Name:
Lovage Essential Oil
Old NHPID Name:
Mace Oil
New NHPID Name:
Mace Essential Oil
Revised Proper and Common Names
In this update, the following non-homeopathic ingredients had their common or proper names revised.
NHPID Name:
Ascophyllum nodosum
New Common Name(s):
Norwegian Kelp
NHPID Name:
Colforsin
Removed Common Name(s):
Forskolin
NHPID Name:
Colforsin
New Common Name(s):
Colforsin
NHPID Name:
Hypromellose
New Common Name(s):
Hydroxypropyl Methylcellulose
NHPID Name:
Tanacetum annuum (Tansy) Essential Oil
Removed Proper Name(s):
Votiga annua
NHPID Name:
Lonicera Japonica (Honeysuckle) Flower Extract
New Common Name(s):
Lonicera Japonica (Honeysuckle) Flower Extract
NHPID Name:
Citrus Grandis Fruit Extract
Removed Common Name(s):
Citrus Grandis (Grapefruit) Fruit Extract
NHPID Name:
Trametes versicolor
New Common Name(s):
Kawaratake, Turkey Tail
NHPID Name:
Capsicum annuum
New Common Name(s):
Cayenne pepper, Chili pepper
NHPID Name:
Tanacetum annuum (Tansy) Essential Oil
New Proper Name(s):
Vogtia annua
NHPID Name:
Citrus Aurantifolia (Lime) Oil
Removed Proper Name(s):
Citrus aurantium
NHPID Name:
Citrus Aurantifolia (Lime) Oil
New Proper Name(s):
Citrus aurantiifolia
NHPID Name:
Citrus Aurantifolia (Lime) Oil
Removed Common Name(s):
Citrus Aurantifolia (Lime) Oil, Lime Oil
NHPID Name:
Citrus Aurantifolia (Lime) Oil
New Common Name(s):
Citrus Aurantifolia Essential Oil, Lime Essential Oil
NHPID Name:
Linaloe Wood Essential Oil
New Common Name(s):
Linaloe Wood Essential Oil
NHPID Name:
Linaloe Wood Essential Oil
Removed Common Name(s):
Linaloe Wood Oil
NHPID Name:
Lovage Essential Oil
New Common Name(s):
Lovage Essential Oil
NHPID Name:
Lovage Essential Oil
Removed Common Name(s):
Lovage Oil
NHPID Name:
Mace Essential Oil
New Common Name(s):
Mace Essential Oil
NHPID Name:
Mace Essential Oil
Removed Common Name(s):
Mace Oil
New Roles
In this update, the roles of the following non-homeopathic ingredients were changed.
NHPID Name:
Cannabis sativa Seed Oil
Old Role:
Non-medicinal
New Role:
Medicinal et Non-medicinal
NHPID Name:
Mace Essential Oil
Old Role:
Medicinal
New Role:
Medicinal and Non-medicinal
Revised Restrictions
In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.
NHPID Name:
Mica
New Route(s) of Adminstration added:
Oral
NHPID Name:
PEG-3 Oleate
New Route(s) of Adminstration added:
Topical
NHPID Name:
Several ingredients
New Route(s) of Adminstration added:
Oral
NHPID Name:
Citrus Aurantifolia (Lime) Oil
New Route(s) of Adminstration added:
Oral
NHPID Name:
Mace Essential Oil
New Route(s) of Adminstration added:
Oral
Other Ingredient Modifications
In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.
NHPID Name:
Mica
New Additional Details added :
Permitted as a colouring agent for dental use. (For Dental)
NHPID Name:
Mica
New Toxicity restriction added:
3% w/w (For Oral)
NHPID Name:
Mica
New Additional Details added :
Mica-based pearlescent pigments may be safely used to color ingested drugs in amounts up to 3 percent, by weight, of the final drug product. The maximum amount of iron oxide to be used in producing said pigments is not to exceed 55 percent, by weight, in the finished pigment. Reference: FDA 2011. 21CFR73 Listing of color additives exempt from certification. Subpart B - Drugs. Sec. 73.1350 Mica-based pearlescent pigments. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?CFRPart=73&showFR=1&subpartNode=21:1.0.1.1.26.2
NHPID Name:
Cannabis sativa
New Sub-ingredient(s) added:
alpha-Linolenic acid, gamma-Linolenic acid, Linoleic acid
NHPID Name:
Plectranthus barbatus
New Sub-ingredient(s) added:
Forskolin
NHPID Name:
Silver diamine fluoride
New Source Ingredient(s) added:
Fluoride, Silver
NHPID Name:
Hypromellose
New NMI Purpose(s):
Emulsion Stabilizer; Viscosity Increasing Agent - Aqueous
NHPID Name:
Hypromellose
New Toxicity restriction added:
In topical products up to 36%, unless additional evidence for safety is submitted.
NHPID Name:
PEG-3 Oleate
New NMI Purpose(s):
Dissolution Enhancing Agent, Emulsifying Agent, Solubilizing Agent
NHPID Name:
Eurycoma longifolia
New Sub-ingredient(s) added:
Eurypeptides, Glycosaponins
NHPID Name:
Magnesium sulfate dihydrate, Magnesium sulfate heptahydrate, Magnesium sulfate trihydrate
New Toxicity restriction added:
Up to 0.7 mg/kg body weight daily expressed as sulfur dioxide. Must be declared as a medicinal ingredient in saline laxative products at or above doses of magnesium sulfate of 10 g/d. Must be declared as a medicinal ingredient in mineral products at or above 50 mg/d as Mg from all sources.
NHPID Name:
Saponaria officinalis
New Source Material(s) added:
Quillaic acid
NHPID Name:
Liquid Sorbitol (Non-crystallising)
New NMI Purpose(s):
Humectant, Sweetening Agent
NHPID Name:
3-Phenyl-1-propanol
New NMI Purpose(s):
Flavour Enhancer
NHPID Name:
Blakeslea trispora
New Source Material(s) added:
Mixed carotenoids
NHPID Name:
Halite
New Source Ingredient(s) added:
Sodium chloride
NHPID Name:
Brassica oleracea var. italica
New Source Ingredient(s) added:
Folate
NHPID Name:
Ethyl lactate
Additional Details removed:
Ethyl lactate is a source of lactic acid, which is an alpha-hydroxy acid. The presence of alpha-hydroxy acids (AHAs), including lactic acid, on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. Ethyl lactate cannot be used in topical natural health products except in accordance with the restrictions for alpha-hydroxy acids set out on the Hotlist unless additional evidence of their safety is submitted. Information regarding the pH of the product and quantity of ethyl lactate it contains must also be provided. Reference: CIH. http://www.hc-sc.gc.ca/cps-spc/cosmet-person/indust/hot-list-critique/hotlist-liste-eng.php#A
NHPID Name:
Aloe Barbadensis Leaf Extract
New Additional Details added :
Flavour enhancer is for dental use only (For Topical)
NHPID Name:
Cannabis sativa Seed Oil
New Toxicity restriction added:
Upper Limit: 10.0 Parts per million
NHPID Name:
Cannabis sativa Seed Oil
New Additional Details added :
Hemp products cannot contain more than 10 ppm of delta-9-tetrahydro-cannabinol (THC), and their production must be in compliance with the Industrial Hemp Regulations.
NHPID Name:
Cannabis sativa Seed Oil
New Source Material(s) added:
Oleic acid
NHPID Name:
Cannabis sativa Seed Oil
New NMI Purpose(s):
Oleaginous Vehicle; Dispersing agent
NHPID Name:
Citrus Aurantifolia (Lime) Oil
New NMI Purpose(s):
Flavour Enhancer
NHPID Name:
Citrus Aurantifolia (Lime) Oil
New Additional Details added :
Flavouring agent only (For Oral)
NHPID Name:
Citrus Aurantifolia (Lime) Oil
New Toxicity restriction added:
When used in cosmetic products, the total concentration of furocoumarin-like substances in the finished product must not exceed 1 ppm.
NHPID Name:
Linaloe Wood Essential Oil
Method(s) of Preparation removed:
Oil, Essential (enfleurage); Oil, Essential (enfleurage) Standardised; Oil, Essential (expression); Oil, Essential (expression) Standardised; Oil, Essential (other methods of preparation); Oil, Essential (other methods of preparation) Standardised
NHPID Name:
Lovage Essential Oil
Method(s) of Preparation removed:
Oil, Essential (enfleurage); Oil, Essential (enfleurage) Standardised; Oil, Essential (expression); Oil, Essential (expression) Standardised; Oil, Essential (other methods of preparation); Oil, Essential (other methods of preparation) Standardised
NHPID Name:
Mace Essential Oil
Method(s) of Preparation removed:
Oil, Essential (enfleurage); Oil, Essential (enfleurage) Standardised; Oil, Essential (expression); Oil, Essential (expression) Standardised; Oil, Essential (other methods of preparation); Oil, Essential (other methods of preparation) Standardised
NHPID Name:
Mace Essential Oil
New NMI Purpose(s):
Flavour enhancer
NHPID Name:
Mace Essential Oil
New Additional Details added :
Flavouring agent only
Monograph Modifications
In this update, the following single ingredient or product monographs were added or modified.
Modification:
Addition of the following new monographs: Active hexose correlated compound - Granule, Active hexose correlated compound - Powder, Poria - Wolfiporia extensa, Cassia cinnamon - Cinnamomum aromaticum, Quercetin, Rutin, Amla - Phyllanthus emblica, and Dong quai - Angelica sinensis.
Modification:
Revisions to the fish oil monograph following consultation
Modification:
Revisions following consultation and conversion of the following from AbLS to monograph: Krill oil, Alpha-Amylase, Fruit Bromelain, Stem Bromelain
AbLS Modifications
In this update, the following abbreviated labelling standards were added or modified.
No Changes.
Controlled Vocabulary Modifications
In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.
No Changes.
Homeopathic Ingredient Modifications
In this update, the following homeopathic ingredients were added or modified.
No Changes.
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