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Drugs and Health Products

Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on June 20, 2017.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the ePLA (electronic Product Licence Application). All new electronic submissions of a Product Licence Application must use the latest version of the e-PLA, namely version 2.3.1, which is available for downloading from e-PLA 2.3.1


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
PEG-5 Ethylhexanoate

Role:
Non-medicinal


NHPID Name:
Hypericum Erectum Flower/Leaf/Stem Extract

Role:
Non-medicinal


NHPID Name:
Camellia Japonica Flower Extract

Role:
Non-medicinal


NHPID Name:
Decyl isostearate

Role:
Non-medicinal


NHPID Name:
Cetyl Stearate

Role:
Non-medicinal


NHPID Name:
C9-12 Alkane

Role:
Non-medicinal


NHPID Name:
Sapindus Mukorossi Peel Extract

Role:
Non-medicinal


NHPID Name:
Immunoglobulin G

Role:
No role


NHPID Name:
C12-13 Pareth-9

Role:
Non-medicinal


NHPID Name:
Saccharina Angustata/Undaria Pinnatifida Extract

Role:
Non-medicinal


NHPID Name:
Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract

Role:
Non-medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

No Changes.


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

No Changes.


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Epimedium sagittatum

New Common Name(s):
Horny goat weed


NHPID Name:
Gentian violet

New Common Name(s):
Basic violet 3


NHPID Name:
D&C Violet No. 2

Removed Proper Name(s):
D&C Violet No. 2


NHPID Name:
Benzyl acetate

New Proper Name(s):
Acetic acid, phenylmethyl ester; Acetic acid, benzyl ester


NHPID Name:
Benzyl acetate

New Common Name(s):
Benzyl acetate


NHPID Name:
Dibromofluorescein

New Common Name(s):
Dibromofluorescein; Solvent red 72


NHPID Name:
Tricholoma magnivelare

New Common Name(s):
American Matsutake


NHPID Name:
Denatured alcohol

New Common Name(s):
Alcohol denat.


NHPID Name:
Sodium dodecyl sulfate

New Common Name(s):
Sodium dodecyl sulfate


NHPID Name:
Formic acid

New Common Name(s):
Formic Acid


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

No Changes.


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Benzoic Acid

New Route(s) of Adminstration added:
Topical


NHPID Name:
Sodium benzoate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Potassium benzoate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Calcium benzoate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Benzyl alcohol

New Route(s) of Adminstration added:
Topical


NHPID Name:
D&C Violet No. 2

Non-medicinal Restriction(s) changed:
For external use only.


NHPID Name:
D&C Violet No. 2

New Restriction Reference added:
CFDR


NHPID Name:
D&C Violet No. 2

Restriction Reference removed:
21CFR74.1602


NHPID Name:
Benzyl benzoate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Dibromofluorescein

Non-medicinal Restriction(s) changed:
For external use only.


NHPID Name:
Benzaldehyde

New Route(s) of Adminstration added:
Topical


NHPID Name:
Phosphorus pentoxide

New Route(s) of Adminstration added:
Dental


NHPID Name:
Balsam Peru Oil

New Non-medicinal Restriction(s) added:
For topical use only, permitted at concentrations equal to or less than 0.4% in products intended for use on intact skin, in adults


NHPID Name:
Myroxylon Pereirae (Balsam Peru) Resin

New Non-medicinal Restriction(s) added:
For topical use, crude exudates are not permitted. Extracts and distillates of Peru balsam are permitted at concentrations equal to or less than 0.4%, in products intended for use on intact skin, in adults.


NHPID Name:
Estragole

New Non-medicinal Restriction(s) added:
For flavour enhancers only, up to 0.05 mg/kg body weight daily.


NHPID Name:
Tarragon Essential Oil

New Route(s) of Adminstration added:
Oral


NHPID Name:
Tarragon Essential Oil

New Route(s) of Adminstration added:
Topical


NHPID Name:
Basil Oil Comoros

New Route(s) of Adminstration added:
Oral


NHPID Name:
Basil Oil European

New Route(s) of Adminstration added:
Topical


NHPID Name:
Birch Tar Oil Rectified

New Non-medicinal Restriction(s) added:
The presence of the ingredient "mixed cresols and derivatives", a major constituent of Birch tar oil, as a prohibited substance on the List of Prohibited and Restricted Cosmetic Ingredients (the Cosmetic Ingredient Hotlist) indicates that there are potentially significant safety issues. This ingredient cannot be used as a non-medicinal ingredient in natural health products without the submission of additional evidence for safety.


NHPID Name:
Sodium dodecyl sulfate

New Route(s) of Adminstration added:
Topical


NHPID Name:
Sodium dodecyl sulfate

New Non-medicinal Restriction(s) added:
For topical use only, up to 55% in rinse-off products, and up to 1% in leave-on products.


NHPID Name:
Ammonium lauryl sulfate

New Non-medicinal Restriction(s) added:
For topical use only, up to 55% in rinse-off products, and up to 1% in leave-on products.


NHPID Name:
TEA-Lauryl sulfate

New Route(s) of Adminstration added:
Topical


NHPID Name:
C14-16 Olefin Sulfonate

Non-medicinal Restriction(s) changed:
For topical use only, up to 2% in leave-on products. Residues of gamma sultones should not exceed 10 ppm for saturated (alkane) sultones, 1 ppm for chlorosultones, and 0.1 ppm for unsaturated sultones.


NHPID Name:
Formic acid

New Route(s) of Adminstration added:
Topical


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Octanoic acid

New NMI Purpose(s):
Fragrance Ingredient


NHPID Name:
Octanoic acid

New NMI Purpose(s):
Surfactant - Cleansing Agent


NHPID Name:
Octanoic acid

New Toxicity restriction added:
Topical use only


NHPID Name:
PEG-6

New Additional Details added :
For topical and buccal use only. Up to 51% in topical products and up to 3% in buccal products.


NHPID Name:
Benzoic Acid

Toxicity Restriction changed:
Acceptable daily intake up to 5 mg/kg bw/day.


NHPID Name:
Benzoic Acid

Additional Details changed:
For topical use, up to 5%.


NHPID Name:
Sodium benzoate

Toxicity Restriction changed:
Acceptable daily intake up to 5 mg/kg bw/day, expressed as benzoic acid equivalents.


NHPID Name:
Potassium benzoate

Toxicity Restriction changed:
Acceptable daily intake up to 5 mg/kg bw/day, expressed as benzoic acid equivalents.


NHPID Name:
Calcium benzoate

Toxicity Restriction changed:
Acceptable daily intake up to 5 mg/kg bw/day, expressed as benzoic acid equivalents.


NHPID Name:
Benzyl alcohol

Toxicity Restriction changed:
Acceptable daily intake up to 5 mg/kg bw/day, expressed as benzoic acid equivalents. Must be declared as medicinal ingredient in throat lozenges in daily doses at or above 100 mg/day, and in anorectal products in concentrations at or above 1% w/w.


NHPID Name:
Brilliant blue FCF

Additional Details removed:
Permitted for internal and external use


NHPID Name:
L-Isoleucine

New Source Material(s) added:
Corynebacterium glutamicum


NHPID Name:
L-Leucine

New Source Material(s) added:
Corynebacterium glutamicum


NHPID Name:
L-Valine

New Source Material(s) added:
Corynebacterium glutamicum


NHPID Name:
Benzyl acetate

Toxicity Restriction changed:
Acceptable daily intake up to 5 mg/kg bw/day, expressed as benzoic acid equivalents


NHPID Name:
Benzyl benzoate

Toxicity Restriction removed:
Acceptable daily intake up to 5 mg/kg bw/day, expressed as benzoic acid equivalents.


NHPID Name:
Benzaldehyde

Toxicity Restriction changed:
Acceptable daily intake up to 5 mg/kg bw/day, expressed as benzoic acid equivalents.


NHPID Name:
Benzophenone-4

Additional Details changed:
For topical use only, up to 1%, if not contributing to the product`s claim(s).


NHPID Name:
Balsam Peru Oil

New Additional Details added :
As a flavour enhancer, up to 0.04 mg per day is permitted.


NHPID Name:
Beef Protein

New Source Material(s) added:
Bos taurus


NHPID Name:
Turkey Protein

New Source Material(s) added:
Bos taurus


NHPID Name:
Chiken Protein

New Source Material(s) added:
Bos taurus


NHPID Name:
Highly branched cyclic dextrin

New Sub-ingredient(s) added:
Glucose


NHPID Name:
Rice bran oil

New Method(s) of Preparation added:
Oil fixed


NHPID Name:
Rice bran oil

New Method(s) of Preparation added:
Oil fixed standardised


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.


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