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Drugs and Health Products

Natural Health Products Ingredients Database

WHAT'S NEW

What's New is a listing of modifications to the NHPID since the last update. This page was most recently revised on April 16, 2021.

ANNOUNCEMENTS

The updates to the NHPID listed below apply to the most recent version of the web-based Product Licence Application (web PLA) form. All new product licence application submissions must use the web PLA form.


New Ingredients

In this update, the following non-homeopathic ingredients were added.

NHPID Name:
Erigeron Bonariensis

Role:
Medicinal


NHPID Name:
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer

Role:
Non-medicinal


NHPID Name:
Ethyl Hexanediol

Role:
Non-medicinal


Removed Ingredients

In this update, the following non-homeopathic ingredients were removed.

NHPID Name:
Polyisobutene

Role:
Non-medicinal


Revised NHPID Names

In this update, the following non-homeopathic ingredients had their NHPID name revised.

Old NHPID Name:
Glyceryl Stearate SE

New NHPID Name:
Glyceryl Stearate SE


Old NHPID Name:
Glyceryl Stearate

New NHPID Name:
Glyceryl Stearates


Old NHPID Name:
Ammonium Acryloyldimethyltaurate/VP Copolymer

New NHPID Name:
Ammonium Acryloyldimethyltaurate/VP Copolymer


Revised Proper and Common Names

In this update, the following non-homeopathic ingredients had their common or proper names revised.

NHPID Name:
Sorbitan Isostearate

Removed Proper Name(s):
Sorbitan, Isooctadecanoate, Sorbitan Monoisostearate


NHPID Name:
Polyisobutylene

New Common Name(s):
Polyisobutene


NHPID Name:
Glyceryl Stearate SE

New Proper Name(s):
Self-emulsifying glyceryl monostearate


NHPID Name:
Glyceryl Stearate SE

New Common Name(s):
Glyceryl stearate SE


NHPID Name:
Glyceryl Stearates

New Proper Name(s):
Glyceryl stearates


NHPID Name:
Glyceryl Stearates

New Common Name(s):
Glyceryl stearates


NHPID Name:
Glyceryl Monostearate

New Proper Name(s):
Octadecanoic acid, monoester with 1,2,3-propanetriol


NHPID Name:
Glyceryl Monostearate

New Common Name(s):
Glyceryl stearate


NHPID Name:
Ammonium Acryloyldimethyltaurate/VP Copolymer

New Proper Name(s):
Ammonium acryloyldimethyltaurate/VP copolymer


NHPID Name:
Ammonium Acryloyldimethyltaurate/VP Copolymer

New Common Name(s):
Ammonium acryloyldimethyltaurate/VP copolymer


NHPID Name:
Cyclohexasiloxane

New Proper Name(s):
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane


NHPID Name:
Cyclohexasiloxane

New Common Name(s):
Dodecamethylcyclohexasiloxane


NHPID Name:
Boric acid

New Proper Name(s):
Boric acid (H3BO3)


New Roles

In this update, the roles of the following non-homeopathic ingredients were changed.

No Changes.


Revised Restrictions

In this update, the following non-homeopathic ingredients underwent a modification related to their restrictions.

NHPID Name:
Sorbitan Isostearate

Non-medicinal Restriction(s) removed:
Acceptable Daily Intake Upper Limit: 25.0 Units: Milligrams/kilogram body weight/day Detail: Up to 25 mg/kg/ body weight daily as the sum of the sorbitan esters Reference: UNAVA


NHPID Name:
Polysorbate 20

Non-medicinal Restriction(s) changed:
Route Of Administration: Topical Detail: When formulated to be non-irritating. Reference: CIR


NHPID Name:
Polyisobutylene

Non-medicinal Restriction(s) changed:
General Route Of Administration: Topical Allowed Purposes: Adhesive , Binder , Film Former , Viscosity Increasing Agent - Nonaqueous Reference: CIR


NHPID Name:
Polyisobutylene

New Non-medicinal Restriction(s) added:
General Route Of Administration: Buccal Allowed Purposes: Masticatory Substance Reference: FCC


NHPID Name:
Glyceryl Stearate SE

Non-medicinal Restriction(s) changed:
General Route Of Administration: Topical Detail: For topical use only. Reference: CIR


NHPID Name:
Glyceryl Stearates

Non-medicinal Restriction(s) changed:
General Route Of Administration: Topical Detail: For topical use only. Reference: ICID


NHPID Name:
Glyceryl Stearates

Non-medicinal Restriction(s) removed:
General Route Of Administration: Oral Reference: MAR


NHPID Name:
Ammonium Acryloyldimethyltaurate/VP Copolymer

Non-medicinal Restriction(s) changed:
General Route Of Administration: Topical Detail: For topical use only, up to 3%. Reference: CIR


NHPID Name:
Cyclohexasiloxane

Non-medicinal Restriction(s) changed:
General Route Of Administration: Topical Detail: For topical use only. Reference: CIR


NHPID Name:
1,2-Hexanediol

Non-medicinal Restriction(s) changed:
General Route Of Administration: Topical Allowed Purposes: Preservative Antimicrobial , Skin Conditioning Agent ,Solvent Detail: Up to 10%. Reference: CIR


NHPID Name:
Boric acid

Non-medicinal Restriction(s) changed:
General Route Of Administration: Topical Allowed Purposes: Denaturant Detail: Up to 0.8%. Reference: DSDAR


Other Ingredient Modifications

In this update, the following non-homeopathic ingredients underwent a modification different from those listed above, such as new source material, new preparation type, or new sub-ingredient relationship, etc.

NHPID Name:
Sorbitan Isostearate

New CAS Registry Number(s) added:
54392-26-6


NHPID Name:
Sorbitan Isostearate

New NMI Purpose(s):
Emulsifying Agent


NHPID Name:
Polysorbate 20

Toxicity Restriction changed:
Upper Limit: 25.0 Units: Milligrams/kilogram body weight/day Detail: Acceptable daily intake up to 25 mg/kg bw/day, as total polyoxyethylene (20) sorbitan esters. Reference: WHO_JECFA


NHPID Name:
Polysorbate 20

New NMI Purpose(s):
Surfactant - Emulsifying Agent; Surfactant - Solubilizing Agent


NHPID Name:
Polyisobutylene

New NMI Purpose(s):
Viscosity Increasing Agent - Nonaqueous


NHPID Name:
Glyceryl Stearate SE

New CAS Registry Number(s) added:
11099-07-3


NHPID Name:
Glyceryl Stearate SE

New NMI Purpose(s):
Emulsifying Agent


NHPID Name:
Glyceryl Stearates

New NMI Purpose(s):
Surfactant - Emulsifying Agent


NHPID Name:
Glyceryl Stearates

Removed NMI purpose(s):
Fragrance Ingredient; Lubricant; Stabilizing Agent


NHPID Name:
Glyceryl Monostearate

New CAS Registry Number(s) added:
31566-31-1


NHPID Name:
Glyceryl Monostearate

New NMI Purpose(s):
Fragrance Ingredient; Surfactant - Emulsifying Agent


NHPID Name:
Cyclohexasiloxane

New CAS Registry Number(s) added:
540-97-6


NHPID Name:
1,2-Hexanediol

New NMI Purpose(s):
Skin-Conditioning Agent


NHPID Name:
Boric acid

Removed NMI purpose(s):
Preservative Antioxidant


Monograph Modifications

In this update, the following single ingredient or product monographs were added or modified.

No Changes.


AbLS Modifications

In this update, the following abbreviated labelling standards were added or modified.

No Changes.


Controlled Vocabulary Modifications

In this update, the following controlled vocabulary (dosage forms, methods of preparation, quality test methods, etc) were added or modified.

No Changes.


Homeopathic Ingredient Modifications

In this update, the following homeopathic ingredients were added or modified.

No Changes.

RemIng

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