CALENDULA - CALENDULA OFFICINALIS - Buccal

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This monograph is intended to serve as a guide to industry for the preparation of Product Licence Applications (PLAs) and labels for natural health product market authorization. It is not intended to be a comprehensive review of the medicinal ingredient.

Notes

Date

August 28, 2018

Proper name(s), Common name(s), Source material(s)

Table 1. Proper name(s), Common name(s), Source material(s)
Proper name(s) Common name(s) Source material(s)
Proper name(s) Part(s) Preparation

Calendula officinalis

  • Calendula
  • Garden-marigold
  • Marigold
  • Pot-marigold
  • Ruddles
  • Scotch-marigold
Calendula officinalis Flower Dried

References: Proper name: USDA 2018; Common names: McGuffin et al. 2000, Wiersema and León 1999; Source material: Bradley 2006, Mills and Bone 2005.

Route of Administration

Buccal

Dosage Form(s)

This monograph excludes foods or food-like dosage forms as indicated in the Compendium of Monographs Guidance Document.

Acceptable dosage forms for the age category listed in this monograph and specified route of administration are indicated in the Compendium of Monographs Guidance Document.

Use(s) or Purpose(s)

Traditionally used in Herbal Medicine to help relieve mucous membrane inflammations of the mouth and/or throat (Bradley 2006; Blumenthal et al. 2000; Saunders 2000; Felter and Lloyd 1983).

Note

Claims for traditional use must include the term "Herbal Medicine", "Traditional Chinese Medicine", or "Ayurveda".

Dose(s)

Subpopulation(s)

Adults 18 years and older

Quantity(ies)

Methods of preparation: Dry, Powder, Non-Standardised Extracts (Dry extract, Tincture, Fluid Extract, Decoction, Infusion)

1 - 4 grams dried flower, per day (Saunders 2000)

Direction(s) for use

Rinse and/or gargle as needed (Saunders 2000).

Duration(s) of Use

No statement required.

Risk Information

Caution(s) and warning(s)

Contraindication(s)

No statement required.

Known adverse reaction(s)

Stop use if hypersensitivity/allergy occurs (Brinker 2010; Mills and Bone 2005).

Non-medicinal ingredients

Must be chosen from the current Natural Health Products Ingredient Database (NHPID) and must meet the limitations outlined in the database.

Storage conditions

No statement required.

Specifications

References Cited

Blumenthal M, Goldberg A, Brinkmann J, editors. Herbal Medicine: Expanded Commission E Monographs. Boston (MA): Integrative Medicine Communications; 2000.

Bradley PR, editor. British Herbal Compendium: A Handbook of Scientific Information on Widely Used Plant Drugs, Volume 2. Bournemouth (UK): British Herbal Medicine Association; 2006.

Brinker F. Herb Contraindications and Drug Interactions, 4th edition. Sandy (OR): Eclectic Medical Publications; 2010. 

Felter HW, Lloyd JU. King’s American Dispensatory, Volume 1, 18th edition. Sandy (OR): Eclectic Medical Publications; 1983 [Reprint of 1898 original].

McGuffin M, Kartesz JT, Leung AY, Tucker AO, editors. Herbs of Commerce, 2nd edition. Silver Spring (MD): American Herbal Products Association; 2000.

McIntyre A. Herbal Treatment of Children - Western and Ayurvedic Perspectives. Toronto (ON): Elsevier Limited; 2005.

Mills S, Bone K. The Essential Guide to Herbal Safety. St. Louis (MO): Elsevier Churchill Livingstone; 2005.

Saunders PR. Herbal monograph: Calendula officinalis (L.), Asteraceae. The Canadian Journal of Herbalism 2000;21(1):14-17.

USDA 2018: ARS, National Genetic Resources Program. Germplasm Resources Information Network (GRIN). Calendula officinalis L. National Germplasm Resources Laboratory, Beltsville (MD). [Accessed 2018 June 19]. Available from: Next link will take you to another Web site  http://www.ars-grin.gov/cgi-bin/npgs/html/tax_search.pl

Wiersema J, Léon B. World Economic Plants: A Standard Reference. Boco Raton (FL): CRC Press LLC; 1999.

References Reviewed

Barnes J, Anderson LA, Phillipson JD. Herbal Medicines, 3rd edition. London (UK): Pharmaceutical Press; 2007.

BHP 1983: British Herbal Pharmacopoeia. Cowling (UK): British Herbal Medical Association; 1983.

Blumenthal M. The Complete German Commission E Monographs. Austin (TX): American Botanical Council; 1998.

Boon H, Smith MJ. The Complete Natural Medicine Guide to the 50 Most Common Medicinal Herbs, 2nd edition. Toronto (ON): Robert Rose Inc; 2004.

Sweetman SC, editor. Martindale: The Complete Drug Reference, 35th edition. London (UK): Pharmaceutical Press; 2007.